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Mol Gen Mikrobiol Virusol ; (4): 23-30, 2006.
Article in Russian | MEDLINE | ID: mdl-17094655

ABSTRACT

An oligonucleotide microarray for detection and identification of orthopoxviruses was developed. Genus specific and orthopoxvirus species-specific regions of the genes encoding chemokine binding and alpha/beta-interferon binding proteins were used as a target. The developed microarray allows the variola, monkeypox, cowpox, vaccinia, camel-pox and ectromelia (mousepox) viruses to be distinguished with a high degree of reliability.


Subject(s)
Gene Amplification , Genes, Viral , Oligonucleotide Array Sequence Analysis , Orthopoxvirus/classification , In Situ Hybridization, Fluorescence , Orthopoxvirus/genetics , Phylogeny
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