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1.
Arch. latinoam. nutr ; 54(3): 264-273, sept. 2004. tab, graf
Article in Spanish | LILACS | ID: lil-401749

ABSTRACT

La lipemia postprandial como factor asociado a aterogénesis esta con el desarrollo de Enfermedades Crónicas No Transmisibles (ECNT). Con el objetivo de determinar factores que modifican lipemia postprandial en respuesta a ingesta mixta de carbohidratos-lípidos en adultos jóvenes de diferentes etnias, se realizó estudio descriptivo no aleatorio con 51 sujetos (23.8±4 años) sanos, con registros de datos personales, clasificación étnica; Test Corto Insulina, Prueba de lipemia postprandial, cálculo de índice masa corporal (IMC) y Area Bajo la Curva (ABC) para evaluación postprandial. Alta porcentaje (80 por ciento) con antecedentes familiares de ECNT y sedentarismo. Los resultados mostraron promedios altos de ABC de glucosa, triglicéridos y Acidos Grasos No Esterificados (AGNE); el ABC de glucosa con diferencias por edad (p menor o igual 0.05), sin diferencias por etnia, género, IMC o sensibilidad a insulina. La curva de trigliceridemia mostró dos picos en mestizos (40 por ciento) y tres en negros (27 por ciento). Sujetos con patrón de cuatro picos tenían IMC elevado; igualmente fue mayor en blancos y mestizos que en negros (p<0.05); mayor en grupo mayores de 29 años y en hombres (p<0.05). El cambio de trigliceridemia sin diferencias por etnia, mayor en hombres (p<0.05) y en sujetos mayores (p<0.05). Correlación (r²= 0.70) entre IMC y trigliceridemia, entre IMC y cambio en trigliceridemia en etnias blancas y negra. Los AGNE descendieron hasta las 2 horas y a las 6-7h alcanzaron concentración mayor que la basal. ABC de Triglicéridos y AGNE mayores que lo reportado. Por alta correlación en casi todas las etnias IMC sería posible indicador de magnitud de trigliceridemia postprandial. Existe respuesta anormal a dieta de grasa, con liberación temprana de AGNE


Subject(s)
Humans , Adult , Area Under Curve , Chronic Disease , Ethnicity , Fatty Acids, Nonesterified , Hyperlipidemias , Risk Factors , Triglycerides , Colombia , Nutritional Sciences
2.
Arch Latinoam Nutr ; 54(3): 264-73, 2004 Sep.
Article in Spanish | MEDLINE | ID: mdl-15807200

ABSTRACT

Postprandial lipemia has been associated with atherogenesis and other non infectious chronic diseases. A descriptive, non aleatory study of 51 healthy young adults (23.8 +/- 4 years) of different ethnic background was carried out to identify possible personal or life style factors associated with the response of plasma lipids after a mixed carbohydrate and lipid load. Personal, family, life styles including use of drugs and activity and ethnic background were recorded. Anthropometrical measurements, a short insulin and postprandial lipemia tests were done. From these observations body mass index (BMI) and area under the curve (AUC) for lipids and glucose were calculated. High mean values were observed in AUC for glucose, triacylglycerol and nonesterified fatty acids (NEFA). Postprandial glucose with differences by age (p=0.05 Bonferroni) but no ethnic, gender, BMI or insulin sensitivity related significant differences were found. Mestizos (40%) showed two, and Negroes three (27%) postprandial triglyceridemia peaks. Noteworthy, subjects presenting four peaks had elevated BMI. Higher triglyceridemia values were found in white and mestizos (p<0.05), in subjects older than 29 and in males (p<0.05). Statistical correlation (r2=0.70) between BMI and triglyceridemia and change in postprandial trigliceridemia was found in white and black subjects. NEFA declined up to the second hour, but at 6-7 hours they reached levels higher than base values. Higher than reported values for UCA and BMI and an abnormal response to fat intake with an early release of NEFA was found. The high correlation between BMI and postprandial trigliceridemia suggests that body mass index could be a good predictor of postprandial trigliceridemia.


Subject(s)
Cholesterol, Dietary/metabolism , Dietary Carbohydrates/metabolism , Ethnicity , Lipids/blood , Postprandial Period/physiology , Adult , Area Under Curve , Blood Glucose/metabolism , Colombia/ethnology , Fatty Acids, Nonesterified/blood , Female , Humans , Male , Triglycerides/blood
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