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1.
PLoS One ; 19(7): e0305410, 2024.
Article in English | MEDLINE | ID: mdl-38985776

ABSTRACT

Anthropometric studies of the scapula have been rare in Spanish populations, nevertheless they are of current interest in forensic anthropology for estimation of sex. Although the estimation of sex is usually carried out on the pelvis and skull, other measurements related to the scapula can be helpful when the skeletal remains are incomplete. Glenohumeral osteoarthritis development is influenced, among others, by the morphology of the scapula, which is one of the less studied aspects. We carried out a descriptive study of anthropometric parameters in a series of 157 scapulae (82 individuals) on bone remains dated to the 20th century from a population of Granada (Southern Spain). Seventy seven (49%) were right-side and 80 (51%) left-side; 72 (45.9%) were from males and 85 (54.1%) from females, and the mean age at death was 70.76±11.7 years. The objective was to develop a discrimination function for sex estimation based on anthropometric parameters of the scapula other than those considered to date, and to analyze the prevalence of glenohumeral osteoarthritis in relation to selected anthropometric parameters. A logistic regression model based on parameters of the upper-external segment of the scapula was done. The obtained formula: 1/1+e^ (- (-57.911 + 0.350*B + 0283*C + 0.249*b + 0.166*a +-0.100*ß) classifies male sex with 98.3% accuracy and female sex with 92.1%. Glenohumeral osteoarthritis was detected in 16.6% of individuals and was related to age (p<0.05), scapular length (p<0.05), glenoid width (p<0.05), glenopolar angle (p<0.05), and α angle (p<0.05) in bivariate analyses but showed no significant associations in multivariate analyses. This approach can be useful for anthropological-forensic identification when scapula remains are incomplete. Glenohumeral osteoarthritis is significantly associated with a smaller α angle.


Subject(s)
Anthropometry , Osteoarthritis , Scapula , Humans , Male , Female , Osteoarthritis/epidemiology , Osteoarthritis/pathology , Scapula/pathology , Scapula/anatomy & histology , Spain/epidemiology , Aged , Middle Aged , Prevalence , Anthropometry/methods , Aged, 80 and over , Shoulder Joint/pathology , Shoulder Joint/anatomy & histology , Sex Determination by Skeleton/methods
2.
Rev. Soc. Andal. Traumatol. Ortop. (Ed. impr.) ; 37(1): 30-38, ene.-mar. 2020. tab, ilus
Article in Spanish | IBECS | ID: ibc-193470

ABSTRACT

OBJETIVO: Análisis de las características demográficas, tipos de tratamiento quirúrgico y resultados de pacientes con lesión de Lisfranc. MATERIAL Y MÉTODOS: Se recogieron los datos de 42 fracturas luxaciones de Lisfranc. Analizamos las características demográficas de nuestra serie y comparamos los resultados entre 25 pacientes intervenidos mediante reducción abierta y fijación interna (RAFI) y 17 mediante artrodesis primaria. RESULTADOS: En relación a las características demográficas, en el 77.8 % de las mujeres el mecanismo de acción fue de baja energía, frente al 45.8% de los hombres con una relación estadísticamente significativa (p = 0.037). No se encontraron diferencias estadísticamente significativas en la escala AOFAS según el mecanismo de acción, la clasificación de la lesión y el tipo de cirugía definitiva. No encontramos una diferencia estadísticamente significativa entre el tipo de tratamiento y las complicaciones con una P de 0.228. No incluimos la retirada de material protocolizada como complicación en el grupo de reducción abierta y fijación interna. CONCLUSIONES: Las lesiones de Lisfranc producidas por mecanismos de baja energía son más frecuentes en mujeres. No se ha podido demostrar la superioridad de un tratamiento respecto a otro en relación a la tasa de complicaciones y los resultados funcionales en la escala AOFAS


OBJECTIVE: Analysis of demographic characteristics, types of surgical treatment and results of patients with Lisfranc lesions. MATERIAL AND METHODS: Based on 42 Lisfranc dislocation, we analyze the demographic characteristics of our series and compare the results between 25 patients treated by open reduction and internal fixation (ORIF) and 17 by primary arthrodesis. RESULTS: In relationto demographic characteristics, in 77.8% of women the mechanism of action was low-energy, compared to 45.8% of men with a statistically significant difference (p 0.037). No statistically significant were found on the AOFAS scale based on mechanism of action, injury classification and type of final surgery. We do not find a statistically significant difference between the type of treatment and complications with a p of 0.228. We do not include the removal of material protocolized as a complication in the ORIF group. CONCLUSIONS: Lisfranc lesions caused by low-energy mechanisms are more common in women. The superiority of one treatment over another in relation to the complication rate and functional results on the AOFAS scale could not be demonstrated


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Foot Injuries/epidemiology , Foot Injuries/therapy , Fracture Dislocation/epidemiology , Fracture Dislocation/surgery , Open Fracture Reduction , Fracture Fixation, Internal , Arthrodesis
3.
Eur Radiol ; 29(2): 620-627, 2019 Feb.
Article in English | MEDLINE | ID: mdl-30062527

ABSTRACT

OBJECTIVE: The aim of this work is to compare the effectiveness of blind and ultrasound-guided injection for Morton's neuroma (MN) to determine which is more appropriate as the initial procedure in conservative treatment. METHODS: This is an evaluator-blinded randomised trial. Of the 56 included patients, 27 were assigned to the blind group (A) and 29 to the ultrasound-guided group (B). Injection includes 1 ml of 2% mepivacaine and 40 mg of triamcinolone in each web space with MN. The included patients were assessed clinically by VAS score and the Manchester Foot Pain and Disability Score (MFPDS). The follow-up was performed at 15 days, 1 month, 45 days, 2 months, 3 months and 6 months after the initial injection. RESULTS: No differences in age or clinical measurements were found at presentation between group A and group B. At the follow-up, the ultrasound-guided group showed greater symptomatic relief at several stages of the follow-up: 45 days (VAS 3.0 ± 0.5 versus 5.5 ± 0.5, p = 0.001; MFPDS: 32.2 ± 1.8 versus 38.8 ± 2.0, p = 0.018), 2 months (VAS: 3.1 ± 0.5 versus 5.6 ± 0.5, p = 0.002; MFPDS: 31.5 ± 1.9 versus 38.5 ± 2.1, p = 0.020) and 3 months (VAS: 3.1 ± 0.4 versus 5.2 ± 0.6, p = 0.010; MFPDS: 31.2 ± 1.9 versus 37.7 ± 2.4, p = 0.047). CONCLUSION: Injection of MN under ultrasound guidance provides a statistically significant improvement at some stages of the follow-up (45 days, 2 and 3 months), compared with blind injection. KEY POINTS: • Ultrasound-guided steroid injections in Morton's neuroma provide short-term pain relief to over 60% of the patients. • Ultrasound-guided injections in Morton's neuroma lead to a higher percentage of short-term pain relief than blind injections. • Ultrasound-guided injections in Morton's neuroma lead to a lower percentage of skin side effects than blind injections.


Subject(s)
Morton Neuroma/diagnostic imaging , Morton Neuroma/drug therapy , Adult , Aged , Anesthetics, Local/administration & dosage , Anesthetics, Local/therapeutic use , Drug Therapy, Combination , Female , Glucocorticoids/administration & dosage , Glucocorticoids/therapeutic use , Humans , Injections, Intralesional , Male , Mepivacaine/administration & dosage , Mepivacaine/therapeutic use , Middle Aged , Pain/drug therapy , Pain Measurement/methods , Single-Blind Method , Triamcinolone/administration & dosage , Triamcinolone/therapeutic use , Ultrasonography, Interventional/methods
4.
Histol Histopathol ; 32(6): 627-637, 2017 Jun.
Article in English | MEDLINE | ID: mdl-27686854

ABSTRACT

OBJECTIVE: Attempts have been made to improve nerve conduits in peripheral nerve reconstruction. We investigated the potential therapeutic effect of adipose-derived mesenchymal cells (ASCs) and ghrelin (GHR), a neuropeptide with neuroprotective, trophic, and developmental regulatory actions, on peripheral nerve regeneration in a model of severe nerve injury repaired with nerve conduits. MATERIAL AND METHODS: The right sciatic nerves of 24 male Wistar rats were 10-mm transected unilaterally and repaired with Dl-lactic-ε-caprolactone conduits. Rats were then treated locally with saline, ASCs, or GHR. At 12 weeks post-surgery, we assessed limb function by measuring ankle stance angle and percentage muscle mass reduction and evaluated the histopathology, immunohistochemistry, ultrastructure, and morphometry of myelinated fibers. MAIN RESULTS: Rats receiving GHR or ASCs showed no significant increased functional recovery in ankle stance angle (p=0.372) but a higher nerve area (p=0.015), myelin area (p=0.046) and number of myelinated fibers (p=0.012) in the middle and distal segments of operated sciatic nerves in comparison to saline-treated control animals. CONCLUSION: These results suggest that utilization of ghrelin or ASCs may improve nerve regeneration using Dl-lactic-ε-caprolactone conduits.


Subject(s)
Caproates , Ghrelin/pharmacology , Guided Tissue Regeneration/methods , Lactones , Mesenchymal Stem Cell Transplantation/methods , Nerve Regeneration , Adipose Tissue/cytology , Animals , Disease Models, Animal , Male , Mesenchymal Stem Cells/cytology , Mice , Nerve Regeneration/drug effects , Random Allocation , Rats , Rats, Wistar , Recovery of Function/drug effects , Recovery of Function/physiology
5.
Pain Med ; 17(8): 1530-41, 2016 08.
Article in English | MEDLINE | ID: mdl-26814301

ABSTRACT

OBJECTIVES: To evaluate widespread pressure pain in patients with chronic plantar heel pain compared with that in healthy controls and to investigate the differences in ultrasound imaging and quality of life between these two groups. METHODS: A total of 22 patients (11 female) with chronic plantar heel pain and the same number of healthy patients, matched according to age and gender, were included in this pilot study. Pressure pain thresholds (PPTs) were bilaterally assessed over the calcaneus bone, the plantar fascia, the first and fifth metatarsals, the soleus muscle, the second metacarpal, and the zygapophyseal joint of C5-C6. Plantar fascia thickness was measured via ultrasound imaging. In addition, quality of life and physical function were assessed using the Short-Form 36 (SF-36) questionnaire and the Foot and Ankle Ability Measure (FAAM) questionnaire, respectively. RESULTS: Analysis of covariance (ANCOVA) results showed significant differences in the PPTs at all points between the groups (P < 0.001), but not between sides. The PPTs were significantly lower in the patients than in the controls at all sites (P < 0.05). The results showed significant increases in fascia thickness at the calcaneus insertion (group: F = 74.172, P ≤ 0.001; side: F = 8.920, P ≤ 0.001) and the middle fascia point (group: F = 133.685, P = <0.001; side: F = 11.414, P = <0.001) on ultrasound in the patient group compared with the matched control group. The analysis also revealed that the patient group had a significantly lower score on every subscale of the SF-36 and FAAM questionnaires (all P < 0.001), except for the mental component, compared with the matched control group. DISCUSSION: Patients suffering from chronic plantar heel pain showed widespread and bilateral hypersensitivity, increased thickness of the plantar fascia in the affected foot, and deterioration in quality of life and physical functioning compared with matched controls.


Subject(s)
Fasciitis, Plantar/complications , Fasciitis, Plantar/pathology , Hyperalgesia/etiology , Quality of Life , Adult , Aged , Chronic Pain , Fasciitis, Plantar/psychology , Female , Humans , Hyperalgesia/psychology , Male , Middle Aged , Pain Measurement , Pain Threshold , Pilot Projects , Pressure , Ultrasonography
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