Speed of lexical activation in nonfluent Broca's aphasia and fluent Wernicke's aphasia.

Rapid, automatic access to lexical/semantic knowledge is critical in supporting the tight temporal constraints of on-line sentence comprehension. Based on findings of "abnormal" lexical priming in nonfluent aphasics, the question of disrupted automatic lexical activation has been the focus of many recent efforts to understand their impaired sentence comprehension capabilities. The picture that emerges from this literature is, however, unclear. Nonfluent Broca's aphasic patients show inconsistent, not absent, lexical priming, and there is little consensus about the conditions under which they do and do not prime. The most parsimonious explanation for the variable findings from priming studies to date is that the primary disturbance in Broca's lexical activation has something to do with speed of activation. Broca's aphasic patients prime when sufficient time is allowed for activation to spread among associates. To examine this "slowed activation" hypothesis, the time course of lexical activation was examined using a list priming paradigm. Temporal delays between successive words ranged from 300 to 2100 msec. One nonfluent Broca's aphasic patient and one fluent Wernicke's patient were tested. Both patients displayed abnormal priming patterns, though of different sorts. In contrast to elderly subjects, who prime at relatively short interstimulus intervals (ISIs) beginning at 500 msec, the Broca's aphasic subject showed reliable automatic priming but only at a long ISI of 1500 msec. That is, this subject retained the ability to access lexical information automatically if allowed sufficient time to do so, a finding that may help explain disrupted comprehension of normally rapid conversational speech. The Wernicke's aphasic subject, in contrast, showed normally rapid initial activation but continued to show priming over an abnormally long range of delays, from 300 msec through 1100 msec. This protracted priming suggests failure to dampen activation and might explain the semantic confusion exhibited by fluent Wernicke's patients.

Neuropsychological assessment in preoperative and postoperative evaluation.

Neuropsychological assessment in the surgical management of the epilepsies includes comprehensive neuropsychological examination for baseline, diagnostic, and follow up purposes, and specialized diagnostic procedures. The developmental competence of the individual provides an organizing principle for psychological work and is reflected in the neurosurgical strategy. Adaptive functioning and psychosocial adjustment are as important in determining outcome as performance on neuropsychological tasks. The techniques and tools of neuropsychological assessment are discussed in this article; presurgical functioning and post-surgical status and management affect outcome.

Developmental differences in part/whole identification.

At issue in the present research was whether or not preschoolers are able to simultaneously perceive multiple aspects of an object. This issue was examined in 2 experiments in which 3-5-year-olds were asked to describe part/whole pictures (e.g., a "house made of crayons"). Prior developmental research has suggested that preschoolers typically fail to name both part and whole aspects of such pictures. In the present study, parts and wholes ranged from relatively "simple" to relatively "difficult" for preschoolers to identify and label. The results showed that even 3-year-olds frequently named both part and whole aspects of our "simple" pictures but were significantly less likely to name both aspects of more "difficult" pictures. Overall, the results suggest that multiple-aspect perception is available as early as 3 years of age, and that preschoolers' failure in previous studies to explicitly identify both part and whole aspects of the same object may reflect failure in verbal or metacognitive skills rather than in children's ability to perceive multiple aspects of an object.