Subject(s)
Bacteremia/cerebrospinal fluid , Bacteremia/microbiology , Meningitis, Bacterial/cerebrospinal fluid , Meningitis, Bacterial/microbiology , Polymerase Chain Reaction/methods , Bacteremia/diagnosis , Child , Child, Preschool , Cohort Studies , Colony Count, Microbial , Female , Gram-Negative Bacteria/isolation & purification , Gram-Positive Bacteria/isolation & purification , Humans , Infant , Infant, Newborn , Male , Meningitis, Bacterial/diagnosis , Meningitis, Meningococcal/cerebrospinal fluid , Meningitis, Meningococcal/diagnosis , Meningitis, Meningococcal/microbiology , Sampling Studies , Sensitivity and SpecificitySubject(s)
Drug Resistance, Microbial , Animals , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Bacteria/drug effects , Cattle , Chickens , Data Collection , Dogs , Drug Industry , Drug Prescriptions , Drug Resistance, Multiple , Drug Utilization , Humans , Penicillin Resistance , Primary Health Care , Sheep , Spain , Swine , Time Factors , Turkeys , Vaccines/administration & dosage , Veterinary MedicineABSTRACT
BACKGROUND: The aim of the study was to assess the number of urinary tract infections, the time between catheterization and the development of bacteriuria, the route taken by the microorganisms and the clinical relevance of infection in patients with bladder catheterization during a short time. METHODS: 83 patients were evaluated by urine culture from the bladder, urethra, the connection of the catheter and the collecting system, and the collecting bag, on a daily basis during the 5 initial days, with clinical and microbiological follow up to 7 days after the removal of the catheter. RESULTS: 32% of patients developed bacteriuria. The mean interval between catheterization and the development of bacteriuria was 4.1 days. 45% of them were detected within 48 hours after catheter insertion. In 50% the causative organisms were detected in the urethra at least 24 hours previously. In no case the microorganism isolated from the connection between the catheter and the collecting system was subsequently isolated form bladder urine. Bacteriuria disappeared spontaneously in 27% of cases. Antibiotic therapy was necessary in 42%. CONCLUSIONS: In the study population most urinary infections were due to previous urethral colonization and subsequent dragging into the bladder, in many cases at the same time of catheterization. A non-negligible number of bacteriurias disappeared spontaneously.
Subject(s)
Urinary Catheterization/adverse effects , Urinary Tract Infections/etiology , Adult , Bacteria/isolation & purification , Bacteriuria/epidemiology , Bacteriuria/etiology , Bacteriuria/microbiology , Candida/isolation & purification , Female , Humans , Male , Middle Aged , Prevalence , Prospective Studies , Time Factors , Urethra/microbiology , Urinary Bladder/microbiology , Urinary Tract Infections/epidemiology , Urinary Tract Infections/microbiologySubject(s)
Intestinal Diseases , Yersinia Infections , Yersinia enterocolitica , Adolescent , Adult , Age Factors , Child , Child, Preschool , Female , Humans , MaleABSTRACT
In a previous study we showed that the lesions of non-bacterial thrombotic endocarditis induced by means of implantation of a catheter in the left ventricle (LV) of the rabbit, undergo inner connectivization and surface endothelialization, which are completed within 2-3 months. In the present study we have investigated whether these histological changes lead to a variation in susceptibility to infective endocarditis (IE). After studying two control groups, we compared the incidence of IE in four groups of 15 rabbits each, inoculated with Streptococcus mitis I, 10, 35 and 70 days after implantation of a catheter in the LV. The frequency of infection was shown to be progressively reduced from 100% to 26.7%. This demonstrates that endothelialization of the catheter and the sterile vegetations protect the animals from IE.
Subject(s)
Cardiac Catheterization/adverse effects , Endocarditis, Bacterial/etiology , Animals , Catheters, Indwelling/adverse effects , Disease Susceptibility , Endocarditis, Bacterial/pathology , Female , Heart Valves/pathology , Heart Ventricles , Male , Myocardium/pathology , Rabbits , Streptococcal Infections/etiology , Streptococcal Infections/pathology , Streptococcus/pathogenicity , Time FactorsABSTRACT
A case of authochthonous mycetoma with Petriellidium boydii as the causal agent, located in the third distal of the lower left leg is reported. The patient was a 35 year old male without any associated pathology. It is assumed that the infecting organism entered the tissues through a lesion caused a few years previously during a traffic accident. On admittance patient was found to have two fistulas on the upper part of the external malleolus from which pus with small yellow granules measuring 1 to 1.5 mm in diameter discharged. Fungus was repeatedly isolated in pure culture in all media in which is was sown. Mycological study of the isolated fungus and histopathology of the lesion are presented. The fungus proved in vitro to be sensitive to miconazole nitrate with minimal inhibitory concentration and minimal fungicide concentration values of less than 0.1 microgram/ml. The third distal of the peroneal bone was excised and arthrodesis of the ankle practiced as conservative treatment and miconazole administered intravenously, Eighteen months later clinical evolution is satisfactory.
