[Usher syndrome]. / Sindrom usher.

We present the case report of two brothers, PF-21 years old and PN-19 years old, to whom the fundus examination, perimetry and dark adaptation established the diagnosis of Retinitis Pigmentosa. The otorhinolaryngology exam and the audiogram revealed, in both cases, bilateral sensorineural deafness. The simultaneous presence of these two conditions completes the clinical findings of Usher syndrome. The common ectodermic origin of the retina and the inner ear could explain this pathological association.

[Sturge Weber syndrome in association with oculo-dermal melanosis]. / Sindrom Sturge-Weber în asociere cu melanoza oculo-dermala. Prezentare de caz.

We present the case report of a 10 years old patient to whom, based on the clinical examination, lab and imaging studies we established the diagnosis. Sturge- Weber syndrome, oculo-dermal melanocytosis-right side. This case is interesting because of the unusual and rare association of these two diseases.

[Anterior uveitis in a juvenile chronic arthritis, oligoarticular form]. / Uveita anterioara la un adolescent cu artrita cronica juvenila, forma oligoarticulara.

We present the case of a 16-year-old male teen-ager admitted in the Ophthalmology Clinic Craiova, diagnosed with Anterior neglected acute uveitis in the left eye. Before and simultaneous with the ocular manifestations, the patient complained of pain on the hips joints. The pediatric examination, based on the clinical features and the laboratory findings, diagnosed him with Juvenile chronic arthritis, oligoarthritis type. The evolution was good under the corticosteroid therapy.

[Retinal lesions in hereditary aplastic anemia]. / Leziuni retiniene în anemia aplastica constitutionala ereditara.

We present a case report of a 6-year-old female child, admitted in the Pediatric Clinic, diagnosed with Aplastic Constitutional Hereditary Anaemia (Fanconi Anaemia). On ophthalmic examination, on the left eye were noted important macular edema and a big preretinal haemorrhage of 4 DP situated on the posterior pole. The treatment of the systemic condition established the involution of the ophthalmic manifestations.

[Takayasu disease--case report]. / Boala Takayasu--consideratii asupra unui caz clinic.

Chronic vasculitis which determines the thickness of the affected arteries, Takayasu disease is an uncommon finding. It is characterized by narrowing of the big arteries beginning from the aortic arch. The result is arterial hypotension, cerebral and retinal ischemic signs, the absence of pulse at the upper limbs. Manifestations includes: vascular narrowing, microaneurysms, hemorrhages, cotton wool spots, vascular occlusions. The authors present the case of a 20-years old female patient with retinal vascular signs, admitted for ocular pain, upper limbs and mastication pains. The clinical examination revealed pulseless radial and brachial arteries, arterial pressure undetermined at both upper limbs.

[Doyne retinal dystrophy--case report]. / Distrofia retiniana "în fagure de miere" Doyne--prezentare de caz.

We present the case of a female patient, 16-years old, whose the fundus examination revealed the presence, in the macular region, of drusen type lesions; the clinical aspect completed with AFG, perimetry, dark adaptation, ERG resulted in the diagnosis of Doyne's honeycomb retinal dystrophy. The disorder, included in the Familial drusen, is due to an inborn error of metabolism localized the RPE. It seems that the defect is in an intercellular matrix protein which leads to the development of abnormal basement membranes.

[Sympathetic ophthalmia--clinical case]. / Oftalmia simpatica --caz clinic.

This paper presents a case of Sympathetic ophthalmia following a penetrating ocular injury produced 30 days ago, of a patient who postponed the presentation to the ophthalmologist.

[Histopathological changes in pseudoexfoliative syndrome]. / Modificari histopatologice în sindromul exfoliativ.

PURPOSE: The purpose of this study was to analyse the structural modifications of the anterior structures of the human eyes with exfoliation syndrome in optic microscopy. MATERIAL AND METHOD: For this we used bulbar conjunctival fragments and the anterior part of the eyes who were eviscerated for the complications of exfoliative glaucoma. For the optic microscopy the human specimens were preserved in paraffin and stained with hematoxiline-eosine, PAS and Congo red method. RESULTS: We have demonstrated in this study using this three coloration that the abnormal material is exfoliative material and not amyloid in all the ocular structures that were studied (conjunctiva, cornea, lens and ciliary body). CONCLUSIONS: All the anterior structures of the eyes that were examined present typical histopathological alterations of the exfoliation syndrome. The Congo red coloration demonstrate that the abnormal material present in all the structures that were examined is exfoliation material and not amyloid.

[Ophthalmic manifestation in icterus--hemorrhagic leptospirosis]. / Leptospiroza ictero-hemoragicâ--manifestari oculare.

We present the case of a 19-year-old male, admitted in the Ophthalmology Clinic for Macular Chorioretinitis, hemorrhagic form. Laboratory findings shown high titres of icterus-hemorrhages leptospirosis.

[Corneal neurotrophic ulcers--clinical and etiopathogenic aspects]. / Ulcere corneene trofice--aspecte clinice si etiopatogenice.

PURPOSE: The aim of this paper is to observe the corneal neurotrophic ulcers in patients with ophthalmic and systemic diseases associated with impairment of the sensory innervation of the cornea. METHODS: We have performed a retrospective study using a lot of patients with corneal neurotrophic ulcers, admitted in Ophthalmology Clinic in 2003-2006. We have analyzed the etiopathogenic factors that have determined the corneal trophic ulcers, the treatment and the complications occurred. RESULTS: The study spot-lighted two main causes responsible for the corneal trophic ulcers: ocular and systemic disorders. For many patients the etiopathogenic factor is multiple. CONCLUSIONS: 1. Corneal neurotrophic ulcer is a severe complication of an ophthalmic or a systemic disorder. 2. The moderate outcome of ophthalmic complications require early treatment, adjusted for each patient. 3. Prevention of the corneal neurotrophic ulcers is the best method of treatment.

[Retinophotography--screening method in diabetic retinopathy]. / Retinofotografia-metoda de screening în retinopatia diabetica.

The paper presents the modern screening method for diabetic retinopathy-the retino-photography. We present our experience on this issue, regarding the patients with diabetic retinopathy screened in Diabetic Eye Department, Ophthalmology Clinic Craiova, between October 2002-June 2005.

[Conjunctival changes in pseudoexfoliative syndrome]. / Modificari conjunctivale in sindromul exfoliativ.

PURPOSE: Histopathologic study of conjunctival biopsy specimens in patients with or without exfoliation syndrome and mature cataract to reveal the presence of exfoliative material. MATERIAL AND METHOD: There were studied a group of patients with different ages who needed surgical cataract extraction; all patients were examined preoperative for the presence of exfoliation syndrome. The conjunctival biopsy specimens were obtained at the end of cataract surgical procedure in eyes both with exfoliation syndrome and in fellow eyes without clinical evidence of the disease. RESULTS: It has been recorded the presence of the exfoliative material in eyes both with exfoliation syndrome and in fellow eyes without clinical evidence of the disease. CONCLUSIONS: Conjunctiva appears to be an independent source of exfoliation material with early detection in preclinical stage of exfoliation syndrome in fellow eyes that appeared to be clinically unaffected.

[Neovascular glaucoma--prevention]. / Glaucomul neovascular--profilaxie.

PURPOSE: The aim of this paper is to analyse the incidence of neovascular glaucoma on a group of patients treated by laser photocoagulation for proliferative diabetic retinopathy and retinal vascular occlusions. MATERIAL AND METHOD: We have studied a group of 277 patients: 112 male and 165 female with ages between 26 and 83 years. 256 patients had proliferative diabetic retinopathy and 21 patients retinal vascular occlusions with ischemic involvement. All this patients were treated with retinal laser photocoagulation. Follow-up period was between 6 months and 2 years. RESULTS: Only 3 patients from the entire group treated with laser photocoagulation had developed neovascular glaucoma. CONCLUSIONS: Prophylactic panretinal photocoagulation is the only method that appears to prevent the neovascular glaucoma and eliminate his devastating complications.

[Retino-photography--screening method for diabetic retinopathy]. / Retinofotografia-metoda de screening în retinopatia diabetica.

The paper presents the modern screening method for diabetic retinopathy--the retino-photography. We are presenting our experience on this issue, regarding the patients with diabetes retinopathy examined in Diabetic Eye Department, Ophthalmology Clinic Craiova, between October 2002-June 2005.

[The adaptometry study in patients with diabetic retinopathy]. / Studiul adaptometriei la bolnavii cu retinopatie diabetica.

PURPOSE: The aim of this paper is to study if the cones and rods adaption is influenced by the degree of the diabetic retinopathy or by the retinal photocoagulation treatment. MATERIAL AND METHOD: I analysed three groups of diabetic patients: the first group without diabetic retinopathy, the second with different stages of diabetic retinopathy without laser treatment and the last one treated by panphotocoagulation. RESULTS: The exploration of the global light and dark adaptation of the retina using Hartinger's adaptometer does not allow a qualitative and selective appreciation of this function. However it suggests quantitative alterations of the terminal limit in patients with diabetic retinopathy treated or not by panphotocoagulation. CONCLUSIONS: The diabetic retinopathy produces minor symptoms of low dark adaptation even in the advanced phase. The diabetic retinopathy induces minimal changes of the graph of the adaptation limits even in the patients without treatment.

[Ocular parasitosis--particular aspects]. / Parazitoze oculare--aspecte particulare.

The goal of this study cases are presented in this study. The first case was emphasized in a patient with an epibulbar tumor and the second case was diagnosed with Toxocara Canis. In both cases the ophthalmoscopic images and the clinical evolution were unusual on the other hand etiological diagnosis in both cases was difficult. In the first case, the surgical procedure was effective, but in the second case the specific antiparasitic treatment could not stop the evolution of corioretinal's lesions; it required laser therapy.

[Diabetes mellitus and glaucoma]. / Diabet zaharat si glaucom.

PURPOSE: The evaluation of the incidence of the open angle glaucoma to the patients with diabetes mellitus compared to the incidence in the general population and the frequency of the neovascular glaucoma. MATERIAL AND METHOD: The work consists in a study of 1700 patients with diabetes mellitus who where examined during 13 years. RESULTS: From 1700 patients with diabetes mellitus, 240 (14.1%) have glaucoma (primary or secondary). Of those 240, 15 (6.2%) have diabetes mellitus type I and 225 (93.7%) have diabetes mellitus type II. Concerning the clinical form of glaucoma, 177 patients (10.4%) have primary glaucoma with open angle, 23 (1.3%) have primary glaucoma with narrow-angle and 40 (2.5%) have secondary glaucoma. CONCLUSIONS: The highly incidence of the primary glaucoma to the patients with diabetes mellitus comparative to the general population can be explained by the vegetative dysfunction in association with diabetes mellitus and the presence of some common immunitary anomalies. The small numbers of cases with neovascular glaucoma means an indicator of the efficiency of the antidiabetic treatment and of the ocular complications of the diabetes mellitus.