Implementation of a Brazilian Cardioprotective Nutritional (BALANCE) Program for improvement on quality of diet and secondary prevention of cardiovascular events: A randomized, multicenter trial

Background Complex percutaneous coronary intervention (PCI) is associated with higher ischemic risk, which can be mitigated by long-term dual antiplatelet therapy (DAPT). However, concomitant high bleeding risk (HBR) may be present, making it unclear whether short- or long-term DAPT should be prioritized. Objectives This study investigated the effects of ischemic (by PCI complexity) and bleeding (by PRECISE-DAPT [PRE dicting bleeding Complications in patients undergoing stent Implantation and Sub sequent Dual Anti Platelet Therapy] score) risks on clinical outcomes and on the impact of DAPT duration after coronary stenting. Methods Complex PCI was defined as ≥3 stents implanted and/or ≥3 lesions treated, bifurcation stenting and/or stent length >60 mm, and/or chronic total occlusion revascularization. Ischemic and bleeding outcomes in high (≥25) or non-high (<25) PRECISE-DAPT strata were evaluated based on randomly allocated duration of DAPT. Results Among 14,963 patients from 8 randomized trials, 3,118 underwent complex PCI and experienced a higher rate of ischemic, but not bleeding, events. Long-term DAPT in non-HBR patients reduced ischemic events in both complex (absolute risk difference: −3.86%; 95% confidence interval: −7.71 to +0.06) and noncomplex PCI strata (absolute risk difference: −1.14%; 95% confidence interval: −2.26 to −0.02), but not among HBR patients, regardless of complex PCI features. The bleeding risk according to the Thrombolysis In Myocardial Infarction scale was increased by long-term DAPT only in HBR patients, regardless of PCI complexity. Conclusions Patients who underwent complex PCI had a higher risk of ischemic events, but benefitted from long-term DAPT only if HBR features were not present. These data suggested that when concordant, bleeding, more than ischemic risk, should inform decision-making on the duration of DAPT. (AU)

Television viewing habits and their influence on physical activity and childhood overweight / Hábito de assistir a televisão e sua influência sobre a atividade física e o excesso de peso infantis

OBJECTIVES: To assess the prevalence of television (TV) viewing habits and their association with childhood sedentary lifestyle and overweight in 8-year-old children, from a cohort in a city in Southern Brazil.METHODS: A prospective cohort study with hospital screening of all births that occurred from September of 2002 to May of 2003. This study refers to a cross-sectional analysis of data collected during the cohort's follow-up conducted at 8 years of age. To evaluate the level of physical activity, a physical activity questionnaire for children and adolescents was used (PAQ-C), during the consultation at 8 years of age.RESULTS: Of the 616 interviewed children, a prevalence of sedentary lifestyle > 70% was found, as well as the habit of watching TV for more than two hours a day in 60% of the sample, regardless of gender (p = 0.30), income (p = 0.57), or family socioeconomic level (p = 0.90). The daily time spent watching TV was inversely associated with physical activity (p < 0.05) and positively associated with excess weight (p < 0.01). Regarding physical activity, running was the most frequently practiced sports modality among the population.CONCLUSIONS: Considering the high prevalence of sedentary lifestyle and children who watch TV for an excessive period of time, it is necessary to motivate such individuals to perform interactive activities, as well as promote a more active lifestyle, by decreasing the time children spend in front of the TV.

OBJETIVOS: Avaliar a prevalência do hábito de assistir a televisão (TV) e sua relação com o sedentarismo infantil e o excesso de peso em crianças aos oito anos pertencentes a uma coorte de uma cidade do Sul do Brasil.MÉTODOS: Estudo de coorte prospectivo, com triagem hospitalar de todos os nascimentos ocorridos entre setembro de 2002 e maio de 2003. O presente estudo refere-se a uma análise transversal dos dados coletados no acompanhamento da coorte ocorrido aos oito anos. Para avaliar o nível de atividade física, um questionário de atividade física para crianças e adolescentes foi usado (PAQ-C), durante a visita aos oito anos.RESULTADOS: Nas 616 crianças entrevistadas, encontrou-se uma prevalência de sedentarismo superior a 70% e o hábito de assistir a TV por um período superior a duas horas diárias em 60% da amostra, independentemente do gênero (p = 0,30), renda (p = 0,57) ou nível socioeconômico (p = 0,90). O tempo diário assistindo a televisão associou-se inversamente à prática de atividade física (p < 0,05) e positivamente ao excesso de peso (p < 0,01). Com relação à atividade física, corrida foi a prática esportiva mais frequente na população.CONCLUSÕES: Diante da elevada prevalência de sedentarismo e de jovens que assistem a TV por um período excessivo, faz-se necessário o estímulo a atividades interativas, bem como a promoção de um estilo de vida mais ativo, com a redução do tempo que jovens dispensam em frente à TV.

Television viewing habits and their influence on physical activity and childhood overweight.

OBJECTIVES: To assess the prevalence of television (TV) viewing habits and their association with childhood sedentary lifestyle and overweight in 8-year-old children, from a cohort in a city in Southern Brazil. METHODS: A prospective cohort study with hospital screening of all births that occurred from September of 2002 to May of 2003. This study refers to a cross-sectional analysis of data collected during the cohort's follow-up conducted at 8 years of age. To evaluate the level of physical activity, a physical activity questionnaire for children and adolescents was used (PAQ-C), during the consultation at 8 years of age. RESULTS: Of the 616 interviewed children, a prevalence of sedentary lifestyle>70% was found, as well as the habit of watching TV for more than two hours a day in 60% of the sample, regardless of gender (p=0.30), income (p=0.57), or family socioeconomic level (p=0.90). The daily time spent watching TV was inversely associated with physical activity (p<0.05) and positively associated with excess weight (p<0.01). Regarding physical activity, running was the most frequently practiced sports modality among the population. CONCLUSIONS: Considering the high prevalence of sedentary lifestyle and children who watch TV for an excessive period of time, it is necessary to motivate such individuals to perform interactive activities, as well as promote a more active lifestyle, by decreasing the time children spend in front of the TV.