1.
Arch Pharm (Weinheim)
; 338(11): 548-55, 2005 Nov.
Article
in English
| MEDLINE
| ID: mdl-16281304
ABSTRACT
The synthesis by microwave irradiation and the biological results of novel benzotriazinone and saccharine derivatives with potential antidiarrhoeal activity is described. Conventional and microwave heatings were compared for the reactions. Good yields and short reaction times are the main advantages of our synthetic route. Among the tested compounds, compound 12 inhibited motility both in in-vitro and in-vivo tests.