Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 7 de 7
Filter
Add more filters











Database
Language
Publication year range
1.
J AAPOS ; 25(2): 97.e1-97.e5, 2021 04.
Article in English | MEDLINE | ID: mdl-33901671

ABSTRACT

BACKGROUND: Rebound tonometry (RBT) can be used to measure intraocular pressure (IOP) in children unable to tolerate measurement with applanation tonometry (AT) while awake. RBT readings are often 2-3 mm Hg higher than AT. We have experienced children with a repeatedly higher difference between RBT and AT measurements (≥6 mm Hg). The purpose of this study was to identify demographic and ocular characteristics that contribute to this artifactuous discrepancy. METHODS: The medical records of pediatric patients with IOP measured by RBT followed by AT within 6 months without intervening surgery or change in medical management were retrospectively reviewed to identify potential predictors of greater difference between RBT and AT readings. RESULTS: A total of 123 eyes of 65 patients were included. In patients with normal IOP (≤24 mm Hg), 18.5% had a ≥6 mm Hg difference between RBT and AT, with RBT being higher. Risk factors for this included presence of persistent fetal vasculature (PFV), increased corneal diameter, and higher initial RBT value (>20). In patients with elevated IOP (>24 mm Hg), 77% had ≥6 mm Hg difference, with larger corneal diameter being the sole predictor. Eyes were less likely to have significant RBT-AT difference if there was corneal opacity or iris abnormalities in eyes with elevated IOP (>24 mm Hg). CONCLUSIONS: In some children, RBT readings are ≥ 6 mm Hg higher than AT readings. Caution should be taken when interpreting RBT values in patients with PFV, increased corneal diameter, and higher initial RBT values.


Subject(s)
Cornea , Tonometry, Ocular , Child , Humans , Intraocular Pressure , Manometry , Reproducibility of Results , Retrospective Studies
3.
Can J Ophthalmol ; 54(4): 445-450, 2019 08.
Article in English | MEDLINE | ID: mdl-31358142

ABSTRACT

OBJECTIVE: To propose a late-onset mechanism for uveitis-glaucoma-hyphema (UGH) syndrome caused by Soemmering ring cataract (SRC) and describe surgical outcomes. DESIGN: Retrospective interventional case series. PARTICIPANTS: Patients developing UGH from anterior displacement of a haptic from a SRC. METHODS: A retrospective chart review was conducted of all patients referred to an anterior segment surgeon (J.C.H.) for intraocular lens (IOL) reposition/exchange between January 2003 and June 2017. Inclusion criteria consisted of all eyes with (i) a diagnosis of UGH syndrome, and (ii) SRC causing anterior displacement of a sulcus-fixated haptic with iris-haptic touch. Outcome measures were change in best corrected visual acuities (BCVA) and resolution of UGH findings. RESULTS: Seven eyes of 7 patients developed UGH secondary to a SRC causing contact between the IOL optic/haptic and the iris/uvea. Diagnosis of UGH was made at a mean 9.1 years after IOL implantation; this was statistically different compared with UGH eyes with other mechanisms from our full UGH cohort (mean 5.4 years; p = 0.0367). The mean preoperative LogMAR BCVA of 0.45 improved to 0.37 after surgical intervention (p = 0.27). Resolution (or nearly full resolution) of UGH findings was achieved in all cases after SRC extraction and lens repositioning/exchange. CONCLUSIONS: Late-onset UGH syndrome can be caused by SRC. Surgical removal of the SRC with IOL repositioning within the capsular bag resolves most if not all components of UGH. Anterior segment ultrasound biomicroscopy is a helpful modality for determining if a SRC is present by demonstrating anatomic relationships commonly obscured by a miotic pupil.


Subject(s)
Cataract Extraction/adverse effects , Glaucoma, Open-Angle/etiology , Hyphema/etiology , Postoperative Complications , Uveitis/etiology , Adolescent , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Glaucoma, Open-Angle/diagnosis , Humans , Hyphema/diagnosis , Male , Microscopy, Acoustic , Middle Aged , Retrospective Studies , Time Factors , Uveitis/diagnosis , Young Adult
4.
Curr Opin Ophthalmol ; 30(5): 314-318, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31313749

ABSTRACT

PURPOSE OF REVIEW: Congenital fibrosis of the extraocular muscles (CFEOM) is caused by abnormal development of the innervation of extraocular muscles. We update the recent literature regarding the clinical, anatomic, genetic, and molecular characteristics of CFEOM. Surgical considerations are addressed. RECENT FINDINGS: CFEOM is broken down into three main subtypes, CFEOM1, CFEOM2, and CFEOM3. Several recent reports of individuals, as well as family pedigrees, highlight the phenotypic heterogeneity of CFEOM. Intracranial and intraorbital radiologic findings have enhanced our understanding of the disease pathophysiology. Molecular genetics research has increased our understanding of the development of extraocular muscles and their innervation as well as pathophysiology of CFEOM. SUMMARY: Our understanding of the pathophysiology of CFEOM has increased with the recent contributions from neuroimaging, molecular genetics, and pedigree analysis. Surgical management of patients with CFEOM continues to be challenging.


Subject(s)
Fibrosis , Ophthalmoplegia , Blepharoptosis/physiopathology , Blepharoptosis/surgery , Eye Diseases, Hereditary/physiopathology , Eye Diseases, Hereditary/surgery , Fibrosis/classification , Fibrosis/physiopathology , Fibrosis/surgery , Humans , Ocular Motility Disorders/physiopathology , Ocular Motility Disorders/surgery , Ophthalmoplegia/classification , Ophthalmoplegia/physiopathology , Ophthalmoplegia/surgery , Phenotype
6.
J AAPOS ; 22(5): 405-407, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30096374

ABSTRACT

We describe the clinical course of an 11-year-old girl diagnosed with lipemia retinalis as the presenting sign of diabetes mellitus type 1 with severe secondary hypertriglyceridemia. By performing serial multimodal imaging studies, we provide a comprehensive description of the clinical manifestations associated with severe hypertriglyceridemia to promote recognition of this rare clinical diagnosis.


Subject(s)
Diabetes Mellitus, Type 1/complications , Hyperlipidemias/etiology , Hypertriglyceridemia/complications , Retinal Diseases/etiology , Child , Female , Humans
7.
Invest Ophthalmol Vis Sci ; 55(11): 7248-55, 2014 Sep 25.
Article in English | MEDLINE | ID: mdl-25257058

ABSTRACT

PURPOSE: To determine whether objective visual function, measured by swept-parameter visual evoked potential (sVEP), is preferentially degraded by neutral density filtration (NDF) in normal control and fellow eyes compared to amblyopic eyes, and to determine whether the response to NDF is a function of stimulus type, using grating and vernier stimuli. METHODS: Monocular Snellen acuity and both grating and vernier sVEP responses were measured in each eye of 23 children or adolescents with amblyopia and 21 visually and neurologically normal children or adolescents. Acuity and sVEP responses were measured with and without a 2.0 log unit neutral density filter before the viewing eye. RESULTS: Suprathreshold sVEP grating responses were more sensitive than vernier to degradation by amblyopia in the unfiltered state and to NDF-induced preferential degradation of responses from fellow and normal control eyes. For threshold measurements, on the other hand, vernier responses were more sensitive to degradation by amblyopia in the unfiltered state and to NDF-induced preferential depression. Threshold vernier responses of amblyopic eyes were paradoxically enhanced by NDF. CONCLUSIONS: Neutral density filtration causes preferential degradation of both threshold and suprathreshold sVEP responses in normal control eyes and fellow eyes of amblyopes, compared to amblyopic eyes. The degradation is stimulus specific and dependent upon whether threshold or suprathreshold responses are measured. Grating responses are more likely to identify suprathreshold abnormalities, while vernier stimuli are more likely to detect threshold abnormalities. These findings may be used to optimize the stimulus parameters and design of future studies utilizing evoked potential techniques in amblyopic subjects.


Subject(s)
Amblyopia/physiopathology , Evoked Potentials, Visual/physiology , Neurons/physiology , Retina/physiopathology , Visual Acuity , Adolescent , Child , Electroretinography , Female , Follow-Up Studies , Humans , Male
SELECTION OF CITATIONS
SEARCH DETAIL