ABSTRACT
A case of post-transplantation pneumonia due to Candida krusei is reported. A 42-year-old man was admitted 28 days after heart transplantation with cough, pleuritic pain and fever. A chest computed tomograph showed multiple alveolar infiltrates bilaterally. He received broad-spectrum antibiotics, fluconazole for oral candidiasis, and cotrimoxazole for possible Pneumocystis carinii. A short-lived period of improvement was followed by respiratory failure. Cultures of bronchial washings grew C. krusei and C. albicans. The infection was documented by histology and culture obtained by transthoracic aspiration. Treatment with amphotericin B was initiated, but the patient died. Histology and culture of a pulmonary specimen, obtained immediately post mortem, further documented the infection with C. krusei.
Subject(s)
Candida/isolation & purification , Candidiasis/complications , Heart Transplantation/adverse effects , Pneumonia/microbiology , Adult , Anti-Bacterial Agents/therapeutic use , Anti-Infective Agents/therapeutic use , Antifungal Agents/therapeutic use , Candidiasis/drug therapy , Fatal Outcome , Fluconazole/therapeutic use , Humans , Immunocompromised Host , Male , Pneumonia/drug therapy , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic useSubject(s)
Bordetella Infections/microbiology , Bordetella bronchiseptica/isolation & purification , Bronchitis/microbiology , Aged , Aged, 80 and over , Bordetella Infections/drug therapy , Bronchitis/drug therapy , Fatal Outcome , Female , Humans , Injections, Intravenous , Meropenem , Recurrence , Sputum/microbiology , Thienamycins/therapeutic useABSTRACT
In Europe, zoonotic filarial infections in humans are caused by two species, Dirofilaria immitis and Dirofilaria repens. These parasites are associated mainly with embolic infarcts of the pulmonary artery and subcutaneous nodules, respectively. An unusual dirofilarial infection in a Greek patient who showed marked eosinophilia and microfilaremia is presented. Although the identification of Dirofilaria species is not conclusive, this report is the first on a case of microfilaremia from a Dirofilaria infection in an immunocompetent patient.
