[T- and B-lymphocyte systems in heart surgery patients in the early postoperative period]. / T- i B-limfotsitarnye sistemy u kardiokhirurgicheskikh bol'nykh v rannem posleoperatsionnom periode.

The number of T- and B-lymphocytes, O cells, the IgA, IgG, IgM content, the lymphocyte transformation in vitro and also the haematological parameters of the white blood were studied in 33 patients with rheumatic heart diseases during the inactive phase of the illness and in 25 operated on patients on the 1st-10th post-operative days. On the 1st-3rd day after the operation marked (3-4-fold) decrease of the absolute number of T- and B-lymphocytes was recorded. The immunological parameters recovered by the 5th-7th days after surgery. On the 10th day they exceed their initial levels. The authors believe it possible to use these data in elaborating the program of immunological control in cardiosurgical patients.

[Rosette-formation phenomenon in autocultures of human venous blood leukocytes]. / Fenomen rozetkoobrazovaniia v autokul'ture leikotsitov venoznoi krovi cheloveka

A method of human venous blood leukocyte culture permits to model immunological processes of an intact organism. Aggregation with lymphoid elements of the central target cell serves as a morphological expression of complicated cell interrelations under conditions of their extracorporeal cultivation. It may be that such interaction of mononuclears in the culture was caused by a special humoral factor generated by lymphocytes. The occurrence of the "rosette" phenomenon in the autoculture permits to suppose that there is a possibility of obtaining an antigenic information by lymphoid elements in the intact organism. The existence of a correlation between the processes of formation of intercellular associations in vitro and the severity of the disease in persons with allergy confirms this supposition.