[Role of cockroaches Blatella germanica in the development of atopic bronchial asthma]. / Rol' tarakanov Blatella germanica v razvitii atopicheskoi bronkhial'noi astmy.

The results of the development of manufacturing technology for the preparation of allergen from the bodies of cockroaches and the physico-chemical characteristics of this allergen are presented. The complex allergological examination of patients with atopic bronchial asthma revealed that 69.3% of such patients were sensitized to house dust, and in 68.4% of them IgE antibodies to cockroach allergens were detected. Patients with atopic bronchial asthma, not sensitized to house dust, were found to have sensitization to Blatella germanica in 12.2% of cases.

[The guanine content in specimens of house dust collected in the living quarters of healthy persons and of patients with atopic bronchial asthma]. / Soderzhanie guanina v obraztsakh domashnei pyli, sobrannoi v zhilishchakh zdorovykh i bol'nykh atopicheskoi bronkhial'noi astmoi.

The content of insoluble guanine fractions originating from micromites in specimens of house dust, collected in the dwellings of 15 healthy persons with no signs of allergy and 64 patients with atopic bronchial asthma (ABA), was studied. The content of these fractions in house dust in the dwellings of ABA patients was significantly higher than that in house dust in the dwellings of healthy persons (0.76 +/- 0.119 in comparison 0.31 +/- 0.040, p < 0.05). A high content of guanine was detected in house dust of the dwellings of 74.1% of ABA patients and 33.3% of healthy persons, which was indicative of the importance of mite contamination in the formation of ABA.