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1.
Klin Med (Mosk) ; 68(12): 20-2, 1990 Dec.
Article in Russian | MEDLINE | ID: mdl-2084329

ABSTRACT

++Non-ezymatic lipid peroxidation (LP) and total lipids (TL) in serum and erythrocytic membranes were studied in 42 hypertensive subjects and 35 chronic sufferers with pyelonephritis accompanied by arterial hypertension. The measurements performed at different phases of the clinical course provided evidence in favour of possible application of LP and TL tests in differentiating essential hypertension from chronic pyelonephritis with arterial hypertension.


Subject(s)
Erythrocyte Membrane/metabolism , Hypertension/blood , Lipid Peroxidation/physiology , Lipids/blood , Pyelonephritis/blood , Adult , Chronic Disease , Female , Humans , Hypertension, Renal/blood , Hypertension, Renal/etiology , Male , Middle Aged , Pyelonephritis/complications
2.
Vopr Med Khim ; 36(3): 69-71, 1990.
Article in Russian | MEDLINE | ID: mdl-2143337

ABSTRACT

Alterations in activity of membrane-bound Ca2(+)-ATPases were shown to depend on the rate of lipid peroxidation in cell membranes of patients with hypertension during the period of crisis. On the basis from these results antioxidants and Ca2(+)-antagonistic drugs could be used for treatment of hypertensive crisis. Monitoring of the disease is possible by means of estimation of the membrane-bound Ca2(+)-ATPases activity.


Subject(s)
Calcium-Transporting ATPases/blood , Erythrocyte Membrane/enzymology , Hypertension/enzymology , Lipid Peroxidation , Membrane Lipids/blood , Adult , Humans , Hypertension/drug therapy , Hypertension/metabolism , Middle Aged , Time Factors
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