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Expert Rev Mol Diagn ; 15(10): 1245-59, 2015.
Article in English | MEDLINE | ID: mdl-26367243

ABSTRACT

Ultrahigh sensitivity and specificity assays that detect Ebola virus disease or other highly contagious and deadly diseases quickly and successfully upstream in Spatial Care Paths™ can stop outbreaks from escalating into devastating epidemics ravaging communities locally and countries globally. Even had the WHO and CDC responded more quickly and not misjudged the dissemination of Ebola in West Africa and other world regions, mobile rapid diagnostics were, and still are, not readily available for immediate and definitive diagnosis, a stunning strategic flaw that needs correcting worldwide. This article strategizes point-of-care testing for diagnosis, triage, monitoring, recovery and stopping outbreaks in the USA and other countries; reviews Ebola molecular diagnostics, summarizes USA FDA emergency use authorizations and documents why they should not be stop-gaps; and reduces community risk from internal and external infectious disease threats by enabling public health at points of need.


Subject(s)
Disease Outbreaks/prevention & control , Hemorrhagic Fever, Ebola/diagnosis , Point-of-Care Systems , Civil Defense , Hemorrhagic Fever, Ebola/epidemiology , Hemorrhagic Fever, Ebola/prevention & control , Humans , International Cooperation , Knowledge Bases , Molecular Diagnostic Techniques , Sensitivity and Specificity
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