ABSTRACT
Glucose, free fatty acids and lipid fatty acid spectrum were studied in arterial and right atrial blood and myocardium of 122 rats during induction and prolongation of artificial hypobiosis (3 and 24 hours) at body temperature of 30 and 20 degrees C. Prolongation of hypobiosis was shown to be accompanied by enhanced participation of free fatty acids in the myocardial energy metabolism. Lipid fatty acid spectrum in the myocardium was characterized by the decrease in linoleic and palmitooleic acid content and the increase in oleic, palmitic, stearic and arachidonic acid levels.
Subject(s)
Hypothermia, Induced , Myocardium/metabolism , Animals , Arteries , Blood Glucose/metabolism , Fatty Acids, Nonesterified/blood , Fatty Acids, Nonesterified/metabolism , Heart Rate , Male , Rats , Respiration , VeinsABSTRACT
Experiments on 32 puppies with a preliminary decrease of immunologic resistance have demonstrated the possibility of the development of purulent destructive pneumonia under the effect of opportunistic microorganisms, such as Proteins, Escherichia coli, Pseudomonas aeruginosa. Histoenzymatic studies of a pathologically changed lung tissue have disclosed appreciable microcirculatory disorders and destruction of the bronchioli and thus promoted the unraveling of the pathogenesis of pulmonary destructive foci.
Subject(s)
Escherichia coli Infections/pathology , Lung/pathology , Pneumonia/pathology , Proteus Infections/pathology , Pseudomonas Infections/pathology , Animals , Dogs , Female , Immunologic Deficiency Syndromes/chemically induced , Immunologic Deficiency Syndromes/complications , Male , Pneumonia/complications , Pneumonia/immunology , ThiotepaABSTRACT
Results obtained in experiments on 10 adult mongrel dogs are offered. A synchronous registration of ultrasonic doppler-cardiograms (USDC) and of the intraventricular pressure continued throughout the experiment helped establish the relation between the pressure range in the left ventricle and the acceleration on the USDC curve. On the ground of the dependence thus obtained 2 indexes are proposed, viz. for an indirect evaluation of the intraventricular pressure (the index of "rated acceleration") and for appraising the contractability or the muyo cardium (the index of "relaxation from acceleration"). The available data might in the future provide for the possibility of devising appliances supplementing and replacing the catheterization.
