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1.
Biomed Khim ; 49(6): 613-22, 2003.
Article in Russian | MEDLINE | ID: mdl-16119090

ABSTRACT

Sera of 80 patients with pyodermias of varius etiology were analysed for interferon-gamma (IF-gamma), antiinterferon autoantibodies (IF-a-AB), corresponding antiidiotypic antibodies (IF-AIAB) and the ratio IF-a-AB/IF-AIAB using ELISA assay. There was no correlation between serum IF-gamma and IF-a-AB. Progression of this disease was characterized by an increase of serum IF-a-AB and a decrease of IF-AIAB. Prolonged duration of this disease also caused the decrease of serum anti IF-a-AB and IF-AIAB. The ratio of IF-a-AB/IF-AIAB increased with severity and duration of this disease.


Subject(s)
Antibodies, Anti-Idiotypic/blood , Autoantibodies/blood , Interferon-gamma/blood , Pyoderma/immunology , Chromatography, Affinity , Humans , Immunoenzyme Techniques , Pyoderma/blood , Pyoderma/etiology , Severity of Illness Index
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