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Mechanisms of the effect of 1,1-dimethyl-3-hydroxybutyl phosphonic acid derivatives on synaptic transmission in neuromuscular junction.
Pryazhnikov, E G; Skorinkin, A I; Garaev, R S; Giniatullin, R A; Vizel, A O; Shchukina, L I.
Bull Exp Biol Med ; 139(4): 437-40, 2005 Apr.
Article in English | MEDLINE | ID: mdl-16027875

ABSTRACT

We studied the effect of homologues derivatives of 1,1-dimethyl-3-hydroxybutyl phosphonic acid on synaptic transmission in frog neuromuscular junction. Here we reviewed general mechanisms of inhibition of the postsynaptic current.


Subject(s)
Neuromuscular Junction/drug effects , Organophosphonates/pharmacology , Synaptic Transmission/drug effects , Animals , Membrane Potentials/drug effects , Neuromuscular Junction/physiology , Ranidae
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