1.
Biodegradation
; 6(2): 173-80, 1995 Jun.
Article
in English
| MEDLINE
| ID: mdl-7772943
ABSTRACT
Trichosporon beigelii SBUG 752 was able to transform diphenyl ether. By TLC, HPLC, GC, GC-MS, NMR- and UV-spectroscopy, several oxidation products were identified. The primary attack was initiated by a monooxygenation step, resulting in the formation of 4-hydroxydiphenyl ether, 2-hydroxydiphenyl ether and 3-hydroxydiphenyl ether (48:47:5). Further oxidation led to 3,4-dihydroxydiphenyl ether. As a characteristic product resulting from the cleavage of an aromatic ring, the lactone of 2-hydroxy-4-phenoxymuconic acid was identified. The possible mechanism of ring cleavage to yield this metabolite is discussed.
Subject(s)
Phenyl Ethers/metabolism , Trichosporon/metabolism , Biotransformation , Chromatography, High Pressure Liquid , Dioxins/toxicity , Environmental Pollution , Magnetic Resonance Spectroscopy , Mass Spectrometry , Oxidation-Reduction , Phenyl Ethers/chemistry , Waste Products
2.
Nahrung
; 20(2): K1-2, 1976.
Article
in German
| MEDLINE
| ID: mdl-822338