ABSTRACT
Dynamics of mass-transport of oxygen, carbon dioxide, and inert gases in lungs, blood, and tissues, as well as gas transport through alveolar capillary and erythrocyte membranes at rest and during exercise under normal and increased ambient pressures, were studied on a mathematical model. The model consists of 34 differential and 58 algebraic equations and makes it possible to estimate the dynamics of changes of over 90 parameters. The effect of various factors: duration of the respiratory cycle, tidal volume, airways resistance, the surface of diffusion, the resistance of alveolar-capillary wall, erythrocyte membrane, ventilation-perfusion relations, pulmonary blood shunts, blood supply to the tissues, Haldane and Verigo-Bohr effect, buffer capacity of the blood, and others) on the mass-transport of gases were quantitatively estimated.
