ABSTRACT
The results of treatment of 224 patients with newly-diagnosed destructive pulmonary tuberculosis were analysed. These patients were divided into 4 groups in relation to the pathologic nature and chemotherapeutic regimen. The most effective results were produced in case of a simultaneous administration of 4 arrtituberculosis drugs irrespective of the pathologic nature. Under the above regimen, cessation of bacteria excretion and curing of cavities occurred in a shorter period of time, and for disseminated pulmonary tuberculosis, these processes were even more frequent than in the patients receiving 3 drugs. The tolerance to the treatment was quite satisfactory.
Subject(s)
Antitubercular Agents/administration & dosage , Lung/drug effects , Tuberculosis, Pulmonary/drug therapy , Adult , Drug Administration Schedule , Drug Therapy, Combination , Humans , Lung/microbiology , Male , Middle Aged , Mycobacterium tuberculosis/drug effects , Time Factors , Tuberculosis, Pulmonary/microbiology , Wound Healing/drug effectsABSTRACT
The causes of 156 deaths in patients with tuberculosis were analyzed within the period from 1984 to 1986. There was detected direct correlation between the deaths and severity of the specific process, complications and concomitant diseases. The proportion of patients observed for not more than a year after the disease statement and patients with relapsing tuberculosis was high among the deaths. This was indicative of unsatisfactory early detection of tuberculous patients, low-quality dispensary observation and insufficient antirelapse measures.
