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J Am Acad Dermatol ; 88(5): 983-998, 2023 05.
Article in English | MEDLINE | ID: mdl-36049582

ABSTRACT

The Epstein-Barr virus (EBV) is a DNA virus that infects 90% of the human population, is responsible for certain cutaneous lymphomas (extranodal NK/T-cell lymhoma, hydroa vacciniforme lymphoproliferative disorder, lymphomatoid granulomatosis, others), and can be associated with a variety of cutaneous manifestations (eg, infectious mononucleosis, severe mosquito bite allergy, chronic active EBV disease, Gianotti-Crosti syndrome). EBV-related skin disorders are frequent in certain populations (South and Cental America, Africa, Asia, and Oceania) and can be diagnostically challenging. The human T-lymphotropic virus type-1 is a retrovirus, which is known to be associated with adult T-cell leukemia/lymphoma, neurologic disorders, but also cutaneous non-neoplastic manifestations (infective dermatitis, infections, and infestations). We performed an updated revision of the clinical dermatologic and histopathologic findings associated with the cutaneous non-neoplastic and preneoplastic disorders occurring in association with the EBV and human T-lymphotropic virus type-1.


Subject(s)
Epstein-Barr Virus Infections , Human T-lymphotropic virus 1 , Lymphoproliferative Disorders , Humans , Herpesvirus 4, Human , Epstein-Barr Virus Infections/complications , Skin/pathology , Lymphoproliferative Disorders/complications
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