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Vestn Ross Akad Med Nauk ; (9): 15-8, 1995.
Article in Russian | MEDLINE | ID: mdl-7580405

ABSTRACT

Only 2 influenza viral proteins--HA and M--have been shown to be active against host T cells, M protein being more active than HA in some tests when interacted with CD4 receptor. M protein stimulated the expression of CD25 receptors and the proliferation of lymphocytes; the activated production of alpha-tumor necrosis factor was undetectable when exposed to virus proteins.


Subject(s)
Hemagglutinins, Viral/metabolism , Influenza A virus , Influenza, Human/virology , Membrane Proteins/metabolism , T-Lymphocytes/immunology , Viral Proteins/metabolism , CD4 Antigens/immunology , Cytotoxicity Tests, Immunologic , Humans , Lymphocyte Activation , Nucleoproteins/immunology
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