ABSTRACT
Artichoke (Cynara scolymus L.), an edible vegetable from the Mediterranean area, is a good source of natural antioxidants such as vitamin C, hydroxycinnamic acids, and flavones. The antioxidant activity of aqueous-organic extracts of artichoke were determined using three methods: (a) free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH(*)) scavenging, (b) ferric-reducing antioxidant power (FRAP), and (c) inhibition of copper(II)-catalyzed in vitro human low-density lipoprotein (LDL) oxidation. In addition, the present study was performed to investigate the ability of the edible portion of artichoke to alter in vivo antioxidative defense in male rats using selected biomarkers of antioxidant status. One gram (dry matter) had a DPPH(*) activity and a FRAP value in vitro equivalent to those of 29.2 and 62.6 mg of vitamin C and to those of 77.9 and 159 mg of vitamin E, respectively. Artichoke extracts showed good efficiency in the inhibition in vitro of LDL oxidation. Neither ferric-reducing ability nor 2,2'-azinobis(3-ethylbenzothiazolin-6-sulfonate) radical scavenging activity was modified in the plasma of the artichoke group with respect to the control group. Among different antioxidant enzymes measured (superoxide dismutase, gluthatione peroxidase, gluthatione reductase, and catalase) in erythrocytes, only gluthatione peroxidase activity was elevated in the artichoke group compared to the control group. 2-Aminoadipic semialdehyde, a protein oxidation biomarker, was decreased in plasma proteins and hemoglobin in the artichoke-fed group versus the control group. In conclusion, the in vitro protective activity of artichoke was confirmed in a rat model.
Subject(s)
Antioxidants/analysis , Antioxidants/pharmacology , Biomarkers/analysis , Cynara scolymus/chemistry , Plant Extracts/pharmacology , Animals , Biphenyl Compounds , Copper/chemistry , Erythrocytes/enzymology , Ferric Compounds/chemistry , Free Radical Scavengers/pharmacology , Glutathione Peroxidase/blood , Lipoproteins, LDL/chemistry , Male , Oxidation-Reduction , Picrates/chemistry , Rats , Rats, WistarABSTRACT
Se analizan 16 casos de parasitismo intestinal alto valorando la sintomatología clínica, hemograma, heces fecales, gastroanálisis, drenaje biliar de diagnóstico, radiología de estómago y duodeno, así como la biopsia intestinal alta, especialmente duodenal. El mayor porcentaje de casos correspondió al Strongiloides stercoralis con ocho casos(AU)
Subject(s)
Humans , Male , Female , Duodenitis , Intestinal Diseases, Parasitic , Strongyloides stercoralisABSTRACT
Se presentan cuantro casos de imágenes lacunares redondeadas gástricas, comprobándose en el acto quirúrgico lo siguiente: en el primer caso un pólipo fibroide inflamatorio, en los casos 2 y 3 fitobezoares concomitando con lesión ulcerosa estenosamente y en el caso no. 4 un quiste enterogénico.Se hace una revisión de las causas más frecuentes de estas imágenes, insistiéndose en el diagnóstico diferencial de las mismas es bastante difícil desde el punto de vista radiológico, siendo el estudio anatomopatológico el único definitivo(AU)
