ABSTRACT
A 17-year-old adolescent girl attended our clinic for a scheduled review of her nevus lesions. She complained about a lesion on the posterior region of her neck, which she had noticed approximately 2 years before. Even though it had not caused any symptoms, its appearance had changed according to her parents. The patient's medical history, as well as that of her family's, was unremarkable.
Subject(s)
Melanoma/pathology , Nevus, Pigmented/pathology , Skin Neoplasms/pathology , Adolescent , Diagnosis, Differential , Female , HumansABSTRACT
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Subject(s)
Humans , Female , Adult , Hypertension/etiology , Kidney Diseases/complications , Hydronephrosis/complications , Nephrolithiasis/complications , Renal Artery Obstruction/complications , Urinary Tract Infections/etiologyABSTRACT
Los leiomiomas son los tumores pélvicos más frecuentes en la mujer. Habitualmente se localizan en el útero siendo inusual encontrarlos en otras localizaciones como la vagina. Se presenta el caso de una paciente de 42 años que acude a consulta por una tumoración de 2 años de evolución en zona vulvovaginal izquierda sin otra sintomatología. Al examen se palpa una tumoración en el labio mayor izquierdo que se extiende hacia fosa isquiorectal de unos 4 cm y que impronta hacia el recto pero sin infiltrarlo. La RMN de pelvis muestra una tumoración de naturaleza sólida-quística vulvar y/o vaginal probablemente de naturaleza neoplásica que no involucra suelo pélvico y que llega hasta periné. Se realiza la extirpación del tumor por vía vaginal sin complicaciones. El estudio anatomopatológico confirmó el diagnóstico de leiomioma benigno. Se hace una revisión sobre el tema (AU)
Uterine leiomyomas are the most common pelvic tumors in women. These neoplasms are usually found in the uterus and their development in other locations, such as the vagina, is unusual. We report the case of a 42-year-old woman who presented with a 2-year history of a tumor in the left vulvovaginal area with no other symptomatology. On examination, a tumor of approximately 4 cm could be palpated inside the left labia majora. The tumor extended to the ischiorectal fossa with an impression in the rectum but without infiltration. Pelvic magnetic resonance imaging showed a solid-cystic vulvar and/or vaginal tumor of likely neoplastic origin which did not involve the pelvic diaphragm and which reached the perineal area. Tumoral enucleation was performed through the vaginal route, with no complications. Pathological study confirmed a benign leiomyoma. A review of the topic is provided (AU)
Subject(s)
Humans , Female , Adult , Leiomyoma/complications , Leiomyoma/diagnosis , Leiomyoma/surgery , Vaginal Neoplasms/complications , Vaginal Neoplasms/diagnosis , Magnetic Resonance Imaging/methods , Magnetic Resonance Imaging , Leiomyoma/physiopathology , Leiomyoma , Vagina/pathology , VaginaABSTRACT
We report a patient who developed cholestatic hepatitis shortly after starting therapy with irbesartan, one of the new, recently marketed angiotensin II antagonists. Serological studies and ultrasonography ruled out viral hepatitis and extrahepatic obstructive jaundice, respectively. A percutaneous liver biopsy showed a portal inflammatory infiltrate with eosinophils and marked cholestatic features in the perivenular area. Irbesartan was discontinued and the patient's jaundice resolved slowly over a period of several weeks, although mild biochemical cholestasis lasted for more than 1 year. There have been seven prior cases of angiotensin II antagonist-induced hepatotoxicity reported in the literature. A class warning for hepatotoxicity for these compounds should probably be considered.
