ABSTRACT
OBJECTIVE: Determine the suitability of transcutaneous bilirubin (TCB) as a tool to assess the effectiveness of phototherapy on patched skin. STUDY DESIGN: A prospective observational study was conducted. We covered a fragment of skin (sternum) with a photo-opaque patch. Several simultaneous TCB and TSB measurements were performed with the JM-105 bilirubinometer. Bland and Altman test evaluated the agreement between bilirubin levels. RESULT: A total of 217 patients were studied, 48.8% were preterm. The mean difference between TSB and TCB before the start of treatment was 1.07 mg/dL. During phototherapy, differences on covered skin were 0.52, 0.27, and 0.39 mg/dL at 24, 48, and 72 h of therapy respectively. The best correlation was observed at 48 h in preterm infants. CONCLUSION: The measurement of TCB on patched skin (PTCB) is useful for monitoring the response to phototherapy in term and preterm infants. We use a patch with a removable flap that eases successive measures without disturbing the patients.
Subject(s)
Bilirubin/analysis , Bilirubin/blood , Jaundice, Neonatal/therapy , Monitoring, Physiologic/instrumentation , Phototherapy , Skin , Female , Gestational Age , Humans , Infant, Newborn , Infant, Premature/blood , Jaundice, Neonatal/blood , Male , Monitoring, Physiologic/methods , Neonatal Screening , Prospective StudiesABSTRACT
INTRODUCTION: Antenatal magnesium sulfate (MgSO4) administration has shown to be effective in minimizing cerebral palsy and severe motor dysfunction at the age of 2 years. The aim of this study is to determine the relationship between the magnesium dose delivered to the mother and the magnesium concentration in the neonates. MATERIALS AND METHODS: A prospective cohort study was conducted on neonates of less than 32 weeks' gestation admitted to the neonatal intensive care unit of University Hospital Complex of Vigo from December 2012 to July 2015. Comparative analysis of magnesium levels between the groups of neonates exposed to MgSO4 and the control group. RESULTS: A total of 118 neonates were included in the study. The mothers of 62 of them had received MgSO4 as a neuroprotective agent. There was a significant correlation between the full dose of MgSO4 received by the mother and the levels of magnesium in the neonate in the first 24 hours of life (r2 = 0.397; p < 0.001). CONCLUSION: The MgSO4 dose received by the mother has a linear relationship with the magnesium levels obtained in neonates.
Subject(s)
Infant, Premature/blood , Magnesium Sulfate/therapeutic use , Magnesium/blood , Neuroprotective Agents/therapeutic use , Case-Control Studies , Cerebral Palsy/prevention & control , Female , Gestational Age , Humans , Infant, Newborn , Intensive Care Units, Neonatal , Linear Models , Male , Motor Disorders/prevention & control , Pregnancy , Prenatal Care/methods , Prospective StudiesABSTRACT
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Subject(s)
Child , Male , Humans , Spinal Cord Compression , Syndrome , Paresis , Diagnosis, Differential , Magnetic Resonance Imaging , Hematoma, Epidural, CranialABSTRACT
AIM: To analyze the relationship between blood pressure in childhood and adolescence and different variables including gender, age, weight, height, body mass index and sexual maturation. METHODS: Cross-sectional study conducted in 1278 boys and girls aged 6 to 18 years old. Two blood pressure measurements were obtained. Mean value in the two measurements was obtained for each of the pressures: systolic (SBP), diastolic IV (DBPIV) and diastolic V (DBPV). Simple and multiple regression analysis were done to evaluate association between variables. RESULTS: 14 years 0.33; SBP boys > 14 years 0.34; DBPIV 0.25; DBPV 0.24) and height (SBP 6-13 years 0.33; SBP girls > 14 years 0.23; SBP boys > 14 years 0.29; DBPIV 0.25; DBPV 0.24) than for age (SBP 6-13 years 0.27; SBP girls > 14 years 0.17; SBP boys > 14 years 0.15; DBPIV 0.23; DBPV 0.22) for each of the blood pressures. Multiple regression analysis demonstrated a significant association between body mass index, height and SBP in the group of boys and girls aged 6-13 years old. No other significant associations were obtained. CONCLUSIONS: Blood pressure values in childhood and adolescence show a positive association with growth and maturation variables. It's of capital importance to considerate not only age, but also height, weight and body mass index when evaluating the blood pressure value of a child.
Subject(s)
Blood Pressure/physiology , Growth/physiology , Adolescent , Child , Cross-Sectional Studies , Female , Humans , Male , Regression Analysis , Sex FactorsABSTRACT
OBJETIVO: Analizar la relación existente entre la presión arterial en la infancia y adolescencia con el sexo del individuo y con variables de crecimiento y maduración, como la edad, el peso, la talla, el índice de Quetelet y el estadio de maduración sexual. MÉTODOS: Estudio transversal realizado en 1.278 niños y niñas de 6 a 18 años de Oviedo. Se efectuaron dos determinaciones de presión arterial, tomándose el valor medio de las dos determinaciones. Se efectuaron análisis de regresión simple y múltiple. RESULTADOS: 14 años, 0,34; PADIV 0,25; PADV 0,24) y talla (PAS 6-13 años 0,33; PAS niñas > 14 años 0,23; PAS niños > 14 años, 0,29; PADIV 0,25; PADV 0,24) que para la edad (PAS 6-13 años 0,27; PAS niñas > 14 años 0,17; PAS niños > 14 años 0,15; PADIV 0,23; PADV 0,22). El estudio de regresión múltiple determinó asociación significativa dentro del grupo de niños y niñas de 6 a 13 años entre la PAS y los valores de talla e índice de Quetelet (p < 0,01). CONCLUSIÓN: Los valores de presión arterial en la infancia y la adolescencia presentan una correlación positiva con las variables de crecimiento y maduración analizadas. Es importante valorar la presión arterial del niño no sólo en función de la edad, sino también de su peso, talla e índice de Quetelet (AU)
