Non-obstetric surgery during pregnancy - an eleven-year retrospective analysis.

BACKGROUND: Diagnosis and management of non-obstetric abdominal pathologies during pregnancy are clinically challenging for both obstetricians and general surgeons. Our aim was to evaluate the outcome of pregnant patients who had undergone non-obstetric abdominal surgery. METHODS: We retrospectively reviewed 76 pregnant patients who had required surgery for non-obstetric abdominal pathologies during pregnancy at our department from January 2005 to December 2015. Data were collected retrospectively from medical records as well as from our institutional perinatal database. We evaluated data for clinical presentation, perioperative management, preterm labor, and maternal and fetal outcomes. RESULTS: The patients' mean age was 29 (interquartile range IQR 25-33) years. Indications for surgery were acute appendicitis in 63%, adnexal pathology in 11%, cholecystolithiasis in 5% and other indications in 21%; surgery was performed in an elective setting in 18% and in an emergent/urgent setting in 82%. In five cases, complications, three of them oncological, called for further surgery. Ninety-seven percent of operations were conducted under general anesthesia. Median skin-to-skin time was 50 (37-80) minutes, median in-hospital stay was 4 (3.5-6) days, and 5 % required postoperative intensive care. Preterm labor occurred in 15%, miscarriage in 7% (none of them directly related to abdominal surgery). CONCLUSION: Abdominal surgery for non-obstetric pathology during pregnancy can be performed safely, if mandatory, without increases in maternal and fetal pathology, miscarriage, and preterm birth rates.

Vertical banded gastroplasty versus adjustable gastric banding: prospective long-term follow-up study.

BACKGROUND: Vertical banded gastroplasty (VBG) has been in clinical use since 1979 and adjustable gastric banding (AGB) since 1985. Because promising results were achieved with the adjustable gastric bands available in the market, some surgeons came to the conclusion that VBG might be entirely abandoned and replaced by the adjustable gastric band. The aim of this study was to compare the long-term outcome of the 2 restrictive procedures. METHODS: Within a 7-year period (1994-2001), 1117 gastric restrictive procedures were performed in the course of a prospective nonrandomized comparative trial. We report the outcomes of 563 VBG and 554 AGB procedures performed by 2 surgeons. The mean body mass index was 46.9 +/- 09.9 kg/m(2) for VBG and 46.7 +/- 07.8 kg/m(2) for AGB. Patient selection was performed by acceptance by 1 of the 2 surgeons. VBG was performed by laparotomy and AGB using laparoscopy. The Bariatric Analysis and Reporting Outcome System (BAROS) was used to evaluate the postoperative health status and quality of life. RESULTS: The mean duration of follow-up was 92 months (range 60-134), with a minimum of 5 years. The overall follow-up rate was 92%. In the short-term 3-year follow-up, no statistically significant difference was registered between AGB and VBG in terms of weight loss, reduction of co-morbidities, or improvement in quality of life. The 30-day mortality rate was .4% (2 patients) for VBG and .2% (1 patient) for AGB. The overall reintervention rate in the long term was 49.7% for VBG and 8.6% for AGB (P <.0001, odds ratio .0937, 95% confidence interval .065-.133), the reoperation rate was 39.9% for VBG and 7.5% for AGB (P <.0001). The excess weight loss was significantly greater in the VBG group after 12 months (58% for VBG versus 42% for AGB, P <.05). At long-term follow-up (mean 92 months), no significant difference in weight loss was registered between the 2 study groups (59% for VBG and 62% for AGB, P = .923). The BAROS score in the short term (3 years) was good to excellent in 94% and 90% of the VBG and AGB groups, respectively. In the long-term follow-up period, the BAROS score was significantly in favor of the AGB group (83.9% versus 57.8%, P <.0001, odds ratio 3.797, 95% confidence interval 2.072-7.125). The overall resolution rate of co-morbidities was 80% in both groups. CONCLUSION: This long-term follow-up study shows that VBG and AGB are effective restrictive procedures to achieve weight loss, and loss of co-morbidities. A statistically significant lower re-intervention and re-operation rate and an improved health status and quality of life were registered for AGB.

Successful antibiotic treatment of Borreliosis associated pseudolymphomatous systemic infiltrates.

The clinical management of late stage Borreliosis can be difficult due to various associated symptoms and signs and cumbersome microbiological tests. We report a case of successful antibiotic treatment of Borreliosis-associated pseudolymphomatous infiltrates in bone marrow and lymph nodes, which were diagnosed by bone marrow trephine biopsy and positron emission tomography.