ABSTRACT
In a boarding school for boys, where routine influenza vaccination is carried out annually, 267 boys were given amantadine (100 mg daily) and 269 received no specific treatment during an influenza A (H1N1) outbreak. 3 boys receiving amantadine and 29 boys receiving no medication had laboratory-proven influenza A. There are circumstances when the prophylactic use of amantadine may be justified for the control of influenza A outbreaks in boarding schools and other institutions where high attack-rates are experienced.
Subject(s)
Amantadine/therapeutic use , Disease Outbreaks/prevention & control , Influenza, Human/prevention & control , Administration, Oral , Adolescent , Adult , Amantadine/administration & dosage , Humans , Influenza A virus/isolation & purification , Influenza Vaccines/administration & dosage , Influenza, Human/transmission , Male , Residential Facilities , United KingdomSubject(s)
Pharynx/microbiology , Streptococcus pyogenes/isolation & purification , Humans , MethodsABSTRACT
An epidemic of echo 19 virus infection in a neonatal unit affecting 12 babies with one death is described. With one exception it was confined to the neonatal unit and medical and nursing staff were also affected. The unit was closed for 9 days, then was disinfected, and there was no recurrence.