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Anticancer Res ; 34(10): 5563-8, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25275056

ABSTRACT

BACKGROUND/AIM: The aim of the present study was to review a single hepatobiliary center experience, the benefit of hepatic metastasectomy in breast cancer liver metastases (BCLM) patients and to identify predictors of survival. PATIENTS AND METHODS: Fifty-two female patients underwent surgery for BCLM between 2002 and 2013. Only patients with liver resections (n=43) were included in the analysis. RESULTS: The median survival of the 43 patients with liver resection was 32.2 months. The factors significantly associated with overall post-hepatectomy survival were estrogen/progesteron receptor (ER/PR) status (p=0.002), node involvement of the primary tumor (p=0.049), size (p=0.005) and number (p=0.006) of the metastatic lesions. The 1-, 3- and 5-year survival rates after curative liver resection were 93.02%, 74.42%, 58.14%, respectively. CONCLUSION: BCLM resection is a safe procedure and offers survival benefit, especially in patients with reduced liver metastatic burden (solitary metastases, diameter of the metastases <5 cm) and positive ER/PR status.


Subject(s)
Breast Neoplasms/pathology , Liver Neoplasms/secondary , Liver Neoplasms/surgery , Adult , Aged , Breast Neoplasms/drug therapy , Breast Neoplasms/mortality , Female , Hepatectomy , Humans , Kaplan-Meier Estimate , Liver Neoplasms/mortality , Middle Aged , Neoplasm Grading , Neoplasm Staging , Prognosis , Risk Factors , Treatment Outcome
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