ABSTRACT
The operational principle of the new mass-spectroscopic device for determining the gas content in blood is based on extracting gases from blood samples into vacuum volume and measuring their content with mass spectrometer. The increased sensitivity and measurement accuracy are achieved by raising the pressure of gases during the process of freezing out the water vapors as well as by making use of calibrating gas. About 0.5-1.0 ml of blood are enough for the analysis. The low pressure in the extraction chamber favors complete removal of gases from the sample without using hemolyzing reagents. Besides O2 and CO2 it is possible to determine the content of other gases including narcotic and inert gases.
Subject(s)
Blood Gas Analysis/methods , Mass Spectrometry/methods , Blood Gas Analysis/instrumentation , Humans , Mass Spectrometry/instrumentationSubject(s)
Atmosphere , Carbon Dioxide/metabolism , Mouth Mucosa/metabolism , Oxygen Consumption , Skin/metabolism , Adolescent , Adult , Child , Humans , Methods , Middle Aged , Mouth Mucosa/blood supply , Partial Pressure , Skin/blood supply , Tongue/metabolismABSTRACT
The Soviet-made mass-spectrometer, model MX-6202 has a number of features that distinguish it from foreign-made devices. The experience with its operation suggests it to be a promising piece of equipment in evaluating the state of gas exchange in the organism, the one that will find wide application in the medical practice. The progress of the mass-spectrometric technique clears the way for detailed, in-depth medical and medico-biological research.
