Assistive technology for ultrasound-guided central venous catheter placement.

This study evaluated the existing technology used to improve the safety and ease of ultrasound-guided central venous catheterization. Electronic database searches were conducted in Scopus, IEEE, Google Patents, and relevant conference databases (SPIE, MICCAI, and IEEE conferences) for related articles on assistive technology for ultrasound-guided central venous catheterization. A total of 89 articles were examined and pointed to several fields that are currently the focus of improvements to ultrasound-guided procedures. These include improving needle visualization, needle guides and localization technology, image processing algorithms to enhance and segment important features within the ultrasound image, robotic assistance using probe-mounted manipulators, and improving procedure ergonomics through in situ projections of important information. Probe-mounted robotic manipulators provide a promising avenue for assistive technology developed for freehand ultrasound-guided percutaneous procedures. However, there is currently a lack of clinical trials to validate the effectiveness of these devices.

Automatic identification of blood vessel cross-section for central venous catheter placement using a cascading classifier.

This paper presents a system that is able to automatically identify, segment, and track the cross-section of the internal jugular vein (IJV) and the common carotid artery (CCA) in an ultrasound image feed during a central venous catheter (CVC) placement procedure. The goal is to provide assistance to the practitioner in order to decrease the probability of complications stemming from inadvertent punctures of the CCA during the procedure. In the system, a modified Star algorithm is implemented to segment and track the blood vessel throughout an ultrasound video feed. A novel algorithm based on a cascading classifier is used to identify the location of the IJV and the CCA for two main tasks: (1) selecting the initial seed point at the start of tracking and (2) validating the segmentation results at each subsequent frame. The classifier uses shape features (vessel area, ellipse fitting error, vessel depth, vessel eccentricity) and pixel-based features (pixel intensity and the histogram of oriented gradients descriptor) to differentiate between vessel and non-vessel structures and also differentiate between the IJV and the CCA. Evaluated on a database of 800 ultrasound images containing the cross-section of both vessels, the cascading classifier was able to identify the IJV and the CCA in 92.25% and 85.13% of the images respectively without any initialization from the user at a maximum processing rate of 40.65 frames per second. This allows identification to be conducted in real-time with existing ultrasound machines.

Microdispensing system via the contacting method.

This paper presents the development of a microdispensing system based on a contacting method, with an aim to lowering production and maintenance cost. The liquid, to be dispensed, is brought into contact with the work piece, thus dispensing a droplet by making use of the adhesion force between the liquid and the work piece. A piezoelectric actuator is employed as the drive for the system to achieve high precision. The control of the system is accomplished with a PID controller; controlling the dispensing process and trajectory tracking.