Subject(s)
Salivary Gland Neoplasms/pathology , Submandibular Gland Neoplasms/pathology , Adenoma/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Carcinoma, Adenoid Cystic/pathology , Child , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local , Submandibular Gland Neoplasms/mortality , Submandibular Gland Neoplasms/surgerySubject(s)
Diverticulum/complications , Intestinal Perforation/etiology , Jejunal Diseases , Aged , Female , HumansABSTRACT
A series of 89 cases of anal carcinoma presenting over a 20-year period is reviewed. The majority were epidermoid carcinomas, 57 arising in the anal canal and 13 at the anal margin. The remainder were melanomas and basal cell carcinomas, and these were not considered further. The main presenting symptoms of epidermoid anal carcinomas were bleeding and pain. Tumours arising in the anal canal were commoner in women whilst those at the margin were more frequent in men. The majority (51/70) had a clinical diagnosis of malignancy made but in 19 cases this was not considered initially. The necessity for routine early histological diagnosis is stressed. Treatment was mainly surgical, either abdominoperineal resection (37 canal, 2 margin) or wide excision (8 canal, 11 margin). The 5 year survival of patients with anal margin tumours was better than those with canal lesions (50 per cent compared with 36 per cent).
Subject(s)
Anus Neoplasms/surgery , Carcinoma, Squamous Cell/surgery , Aged , Anus Neoplasms/mortality , Anus Neoplasms/pathology , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/pathology , Female , Humans , Male , Middle Aged , PrognosisSubject(s)
Mallory-Weiss Syndrome , Adolescent , Adult , Aged , Female , Humans , Male , Mallory-Weiss Syndrome/diagnosis , Mallory-Weiss Syndrome/etiology , Mallory-Weiss Syndrome/surgery , Middle AgedABSTRACT
The clinicopathological details of eight cases of ulcerative colitis complicated by carcinoma of the colon are described. There was a total of 14 primary colonic cancers, six of which were not detected before pathological examination of the resection specimens. The reason for this may be related to atypical tumour growth patterns. Three occurred in flat mucosa, one in a mucosal plaque lesion, and another in polypoidal mucosa. The occurrence, distribution, and morphology of mucosal dysplasia were noted in both resection specimens and biopsies taken at varying stages before resection. Tumour was associated with normal and adjacent dysplastic mucosa of varying grades. The extent and grade of dysplasia were not reliable indicators of tumour differentiation or subsequent clinical outcome. Only two cancers were poorly differentiated. In five cases a total of 23 mucosal biopsies were taken, all less than 12 months before resection. Three rectal biopsies were graded positive for dysplasia and three colonic biopsies indefinite for dysplasia. The subsequent resection specimens showed both dysplastic and carcinomatous changes. Three rectal and 14 colonic biopsies were graded negative for dysplasia despite positive findings in the subsequent resection specimens. This anomaly is partly attributed to the patchy nature of dysplasia in colitic mucosa. Two cases illustrate the possibility of dysplasia pursuing a rapidly progressive course. The mucosal changes of ulcerative colitis were assessed using a recently introduced and standardised international classification.
Subject(s)
Colitis, Ulcerative/complications , Colonic Neoplasms/etiology , Adolescent , Adult , Child , Child, Preschool , Colitis, Ulcerative/pathology , Colon/pathology , Colonic Neoplasms/pathology , Female , Humans , Intestinal Mucosa/pathology , MaleSubject(s)
Anus Neoplasms/surgery , Melanoma/surgery , Aged , Anus Neoplasms/mortality , Female , Humans , Male , Melanoma/mortality , Middle Aged , Prognosis , Time FactorsABSTRACT
As a result of terrorist incidents, 482 patients were seen at a district hospital between September 1972 and December 1980. Details of 339 bomb victims and 115 gunshot victims were available for analysis. Most patients in both categories suffered injuries not affecting vital structures and there was an admission rate of 42 per cent for bomb victims and 81 per cent for gunshot victims. Five patients died in hospital as a result of explosions, and 12 of gunshot wounds. The majority of patients (72 per cent) were seen outside normal working hours (9.00 am-5.00 pm). Initial emergency treatment was carried out at Craigavon Area Hospital and ultimately 41 cases were transferred for either security or medical reasons.
Subject(s)
Wounds and Injuries/therapy , Adolescent , Adult , Aged , Blast Injuries/therapy , Child , Female , Hospitals, District , Humans , Male , Middle Aged , Northern Ireland , Violence , Wounds, Gunshot/therapySubject(s)
Braces , Casts, Surgical , Femoral Fractures/therapy , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle AgedABSTRACT
As result of terrorist incidents, 482 patients were seen at a district hospital between September 1972 and December 1980. Details of 332 bomb victims and 115 gunshot victims were available for analysis. Most patients in both categories suffered injuries not affecting vital structures and there was an admission rate of 42 per cent for bomb victims and 81 per cent for gunshot victims. Five patients died in hospital as a result of explosions, and 12 of gunshot wounds. The majority of patients (72 per cent) were seen outside normal working hours (9.00 am-5.00 pm). Initial emergency treatment was carried out at Craigavon Area Hospital and ultimately 41 cases were transferred for either security or medical reasons(AU)
