Androgen insensitivity syndrome after preimplantation genetic diagnosis for sex selection: a case report.

OBJECTIVE: To report the first case of androgen insensitivity syndrome after preimplantation genetic diagnosis (PGD) for sex selection. DESIGN: Case report. SETTING: The Farah Hospital (a private tertiary referral fertility center). PATIENT(S): A healthy woman with three daughters underwent PGD for sex selection, seeking a male baby. INTERVENTION(S): PGD was done and the woman became pregnant. Ultrasound examination showed female phenotype. Amniocentesis was performed and culture of cells confirmed XY karyotype. RESULT(S): Karyotyping confirmed the diagnosis of XY genotype and pregnancy was terminated. CONCLUSION(S): Although androgen insensitivity syndrome is very rare, it can occur in cases of PGD for sex selection.