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1.
Behav Sci (Basel) ; 14(6)2024 May 26.
Article in English | MEDLINE | ID: mdl-38920780

ABSTRACT

This study examined 430 Chinese college students' engagement in arts activities and the psychological benefits derived from such activities. The research differentiated between various types of arts participation and ways of involvement and examined four potential positive psychological outcomes. The findings revealed correlations between (1) creative participation in the performing arts, 'flow', and aesthetic emotions; (2) consumptive participation in the visual arts and aesthetic emotions; and (3) creative participation in the literary arts and ego identity. Holistic arts participation demonstrated a significantly positive relationship with flourishing. A path analysis showed that flow experience and aesthetic emotions served as mediators in the mechanism through which holistic arts participation affected flourishing, with a chained mediation effect from flow experience to ego identity. This study confirms that arts participation is an effective pathway for individual flourishing and that more diverse and profound engagement in the arts can lead to sustained and widespread happiness.

2.
Heliyon ; 9(12): e23118, 2023 Dec.
Article in English | MEDLINE | ID: mdl-38144271

ABSTRACT

Background: The relationship between leisure sedentary behavior (LSB) and periodontitis risk remains unclear in terms of causality and the potential mediating effects of intermediate factors. Materials and methods: Using the aggregate data of several large-scale genetic association studies from participants of European descent, we conducted a univariate, two-step, and multivariate Mendelian random (MR) analysis to infer the overall effect of LSB on periodontitis, and quantified the intermediary proportion of intermediary traits such as smoking. Results: Our findings indicated that per 1-SD increase (1.87 h) in leisure screen time (LST), there was a 23 % increase in the risk of periodontitis. [odds ratios (95 % CI) = 1.23 (1.04-1.44), p = 0.013]. Smoking was found to partially mediate the overall causal effect of LST on periodontitis, with a mediation rate of 20.7 % (95 % CI: 4.9%-35.5 %). Multivariate MR analysis demonstrated that the causal effect of LST on periodontitis was weakened when adjusting for smoking, resulting in an odds ratio of 1.19 (95 % CI: 1.01-1.39, p = 0.049) for each 1 standard deviation increase in exposure. Conclusion: The study provides evidence of a potential causal relationship between LSB characterized by LST and periodontitis, thereby further supporting the notion that reducing LSB is beneficial for health. Furthermore, it confirms the role of smoking as a mediator in this process, suggesting that inhibiting smoking behavior among individuals with long-term LSB may serve as a strategy to mitigate the risk of periodontitis.

3.
Cell Reprogram ; 25(2): 53-64, 2023 04.
Article in English | MEDLINE | ID: mdl-37053510

ABSTRACT

Exosomes are one kind of small-cell extracellular membranous vesicles that can regulate intercellular communication and give rise to mediating the biological behaviors of cells, involving in tissue formation, repair, the modulation of inflammation, and nerve regeneration. The abundant kinds of cells can secret exosomes, among them, mesenchymal stem cells (MSCs) are very perfect cells for mass production of exosomes. Dental tissue-derived mesenchymal stem cells (DT-MSCs), including dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, stem cells from human periodontal ligament (PDLSCs), gingiva-derived mesenchymal stem cells, dental follicle stem cells, tooth germ stem cells, and alveolar bone-derived mesenchymal stem cells, are now known as a potent tool in the area of cell regeneration and therapy, more importantly, DT-MSCs can also release numerous types of exosomes, participating in the biological functions of cells. Hence, we briefly depict the characteristics of exosomes, give a detailed description of the biological functions and clinical application in some respects of exosomes from DT-MSCs through systematically reviewing the latest evidence, and provide a rationale for their use as tools for potential application in tissue engineering.


Subject(s)
Exosomes , Mesenchymal Stem Cells , Humans , Periodontal Ligament , Gingiva , Stem Cells , Cell Differentiation/physiology
4.
J Youth Adolesc ; 52(3): 547-560, 2023 Mar.
Article in English | MEDLINE | ID: mdl-36427160

ABSTRACT

Parental emotion socialization is highly associated with children's internalizing and externalizing problems. However, research on parent-child discrepancies in parental emotion socialization perceptions and their relationship with children's developmental outcomes remains limited. This study explores the relationship between parent-child discrepancies in their reports of parental emotion socialization and children's internalizing/externalizing problems in Chinese families. The participants were 390 children (55% girls, Mage = 11.70 years, SDage = 1.17) and their primary caregivers (68% mother, Mage = 39.52 years, SDage = 5.23). A latent profile analysis identified three profiles of parent-child discrepancies in supportive parental emotion socialization and four profiles in non-supportive parental emotion socialization. Children with more negative perceptions of parental emotion socialization than their parents exhibited the most internalizing and externalizing problems. The parent-child perception difference of the supportive dimension connected to internalizing and externalizing problems, while the perception difference of the non-supportive dimension connected only to internalizing problems. These findings advocate for the conceptualization of perceptions of parent-child discrepancies within family dynamics, which may predict children's developmental outcomes.


Subject(s)
East Asian People , Socialization , Female , Humans , Child , Infant , Adult , Child, Preschool , Male , Parents/psychology , Emotions , Parent-Child Relations
5.
Sensors (Basel) ; 22(19)2022 Oct 01.
Article in English | MEDLINE | ID: mdl-36236562

ABSTRACT

To achieve fast and accurate channel estimation of reconfigurable intelligent surface (RIS)-assisted multiple-input single-output (MISO) systems, we propose an accelerated bilinear alternating least squares algorithm (ABALS) based on parallel factor decomposition. Firstly, we build a tensor model of the received signal, and expand it to obtain the unfolded forms of the model. Secondly, we derive the expression of the estimation problem of two channels based on the unfolded forms to transform the problem into a cost function problem. Furthermore, we solve the cost function problem by introducing a simpler iterative optimization constraint and linear interpolation. Finally, we provide a strategy on the receiver design based on the feasibility conditions discussed in this paper, which can guarantee the uniqueness of the channel estimation problem. Simulation results show that the proposed algorithm can obtain a faster estimation speed and less iteration steps than the alternating least squares (ALS) algorithm, and the accuracy of the two algorithms is very close.

6.
Sensors (Basel) ; 22(15)2022 Aug 07.
Article in English | MEDLINE | ID: mdl-35957465

ABSTRACT

In a reconfigurable intelligent surface (RIS) assisted millimeter Wave (mmWave) communication system, the channel coefficient increases exponentially with the number of RIS elements which results in expensive pilot overhead. Most previous works have proposed some channel estimation algorithms for the estimation accuracy of cascaded channels, which have improved the estimation accuracy, but the pilot overhead is discouraging in the estimation process. To improve the channel estimation accuracy with reduced pilot overhead, we propose a two-stage channel estimation protocol by exploiting semi-passive elements and the coherent time difference of the channel, where the quasi-static channel between the base stations (BS) and RIS is estimated at the RIS, and the user (UE)-RIS time-varying channel is estimated at the BS. In the first stage, we formulate the BS-RIS channel estimation as a mathematical optimization problem by an iterative weighting method and then propose a gradient descent (GD)-based algorithm to solve it. In the second stage, we first transform the received the UE-RIS signal model into an equivalent parallel factor (PARAFAC) tensor model and estimate the UE-RIS channel by the least-squares (LS) algorithm. The simulation results show that the proposed method has better estimation accuracy than the LS, compression sensing (CS) and minimum mean square error (MMSE) methods with less pilot overhead, and the spectral efficiency is improved by at least 10.5% compared to the other three methods.

7.
Sensors (Basel) ; 22(16)2022 Aug 18.
Article in English | MEDLINE | ID: mdl-36015972

ABSTRACT

In order to investigate the effect of cooperative Intelligent Reflecting Surface (IRS) in improving spectral efficiency, this paper explores the joint design of active and passive beamforming based on a double IRS-assisted model. First, considering the maximum power constraint of the active vector and the unit modulus constraint of the cooperative passive vector, we establish the non-linear and non-convex optimization problem of multi-user maximization weighted sum rate (WSR). Then, we propose an alternating optimization (AO) algorithm to design the active vector and the cooperative passive vector based on fractional programming (FP) and successive convex approximations (SCA). In addition, we conduct a study on the optimization of the passive reflection vector under discrete phase shift. The simulation results show that the proposed beamforming scheme of double IRS-assisted model performs better than the conventional single IRS-assisted model.

8.
Front Psychol ; 13: 882815, 2022.
Article in English | MEDLINE | ID: mdl-35814109

ABSTRACT

This study aimed to investigate the factor structure and measurement invariance of the Brief Symptom Inventory-18 (BSI-18) among Chinese adults. A sample comprising 1,839 adults from four cities in Shaanxi province completed the BSI-18 and background information. The best-fitting factor structure model of the BSI-18 was verified by confirmatory factor analyses, and multigroup confirmatory factor analyses were performed to test the measurement invariance. The results indicated that the three-factor bi-factor model fitted the current data best (χ 2 = 468.861, df = 117, CFI = 0.939, TLI = 0.920, RMSEA = 0.040, BIC = 47044.977). The configural, metric, scalar, and strict invariance models all had acceptable model fit indexes across genders, and the configural, metric, scalar invariance models with different living areas and educational levels were all acceptable. Overall, the three-factor bi-factor model of the BSI-18 shows a good fit for use with Chinese adults, making it a viable tool for effectively measuring the mental health of Chinese adults.

9.
BMC Med Imaging ; 22(1): 104, 2022 05 29.
Article in English | MEDLINE | ID: mdl-35644617

ABSTRACT

INTRODUCTION: The aim of this study was to evaluate the prevalence and characteristics of C-shaped root canals in maxillary first (MFMs) and second (MSMs) molars in a Southwestern Chinese population using cone-beam computed tomographic (CBCT). METHODS: CBCT images of MFMs (n = 1488) and MSMs (n = 1547) from 1508 subjects enrolled in Guiyang Hospital of Stomatology between July 2018 to February 2021 were evaluated for the incidence and types of C-shaped root canals. Differences by age, sex, left or right side, and bilateral symmetry were also evaluated. RESULTS: C-shaped root canals were present in 2.93% MFMs and MSMs (n = 3035) in the Southwestern Chinese population. A significant higher incidence was observed in the MSMs (5.24%) than in the MFMs (0.54%). Increased incidences were noted in teeth with fused root. Two major types and 5 subtypes of C-shaped canal system of maxillary molars were defined, and the most common type of C-shaped canals is fusion of mesial-buccal (MB) and distal-buccal (DB) canals (Type I subtype C). No significant gender and age differences were noted in the prevalence of C-shaped root canals in this population, and no significant difference was seen in its incidence in the left or right MFMs and MSMs. The bilateral occurrence was observed in 1.27% of the patients. CONCLUSION: C-shaped root canals are more frequently present in MSMs than in MFMs in the Southwestern Chinese population, with Type I subtype C (MB-DB canal fusion) as the most common subtype and low incidence of bilateral symmetry.


Subject(s)
Spiral Cone-Beam Computed Tomography , Tooth Root , China/epidemiology , Cone-Beam Computed Tomography/methods , Humans , Molar/diagnostic imaging
10.
Front Psychol ; 11: 1312, 2020.
Article in English | MEDLINE | ID: mdl-32670160

ABSTRACT

This study aimed to explore the characteristics and influencing factors of violence exposure in real life among Chinese college students. A sample of 375 college students was randomly selected to complete three questionnaires. The results indicated that participants had higher scores as victims and witnesses on violence exposure in community than they did in family. Male students had higher scores than females in both family and community violence exposure. Subjects with lower father's education level scored significantly higher than others in family violence exposure by victimization and community violence exposure by witnessing and victimization. Participants growing up in rural areas had significantly higher scores than others in family violence exposure by victimization and community violence exposure by witnessing. Finally, those subjects with siblings reported higher scores than those from only child families in family violence exposure by witnessing. Multiple regression analysis showed that deviant behaviors of peers, gender, and single-child status were significant influencing factors of respondent violence exposure. More efforts should be taken to effectively cope with existing violence exposure in college students and minimize the potential of future exposure.

11.
PLoS One ; 12(10): e0186837, 2017.
Article in English | MEDLINE | ID: mdl-29065129

ABSTRACT

OBJECTIVE: This study sought to examine the sources of inequity in health examination service utilization by women from underdeveloped areas in western China. METHODS: Based on data from the 5th National Health Service Survey in Shaanxi province, women's utilization of health examination services was examined according to gynecological, cervical smear, and breast examination rates. The equity of health examination service utilization by 15- to 64-year-old women and the factors contributing to inequity were determined using the health concentration index, decomposition of the concentration index, and the horizontal inequity index. RESULTS: The examination rates for gynecological, cervical smear, and breast exams for 15- to 64-year-old women in Shaanxi province were 40.61%, 27.08%, and 24.59%, respectively. The horizontal inequity indices of gynecological, cervical smear, and breast examination rates were 0.0480, 0.0423, and 0.0764, respectively, and each examination rate was higher for wealthy individuals. The contribution rates of economic status to the inequalities in gynecological, cervical smear, and breast examination rates were 65.80%, 74.31%, and 56.49%, respectively. The contribution rates of educational status to the inequalities in gynecological, cervical smear, and breast examination rates were 21.01%, 14.83% and 30.00%, respectively. The contribution rates of age to the inequalities in gynecological, cervical smear, and breast examination rates were 25.77%, 26.55%, and 18.40%, respectively. CONCLUSIONS: Women's health examination rates differed between populations with different socio-demographic characteristics. There is pro-wealth inequality in each examination rate. This study found that financial status, age, and education level were the main reasons for the unequal utilization of health examination services.


Subject(s)
Medically Underserved Area , Physical Examination , Women's Health Services/statistics & numerical data , Adolescent , Adult , China , Female , Healthcare Disparities , Humans , Middle Aged , Papanicolaou Test , Young Adult
12.
Int J Equity Health ; 16(1): 186, 2017 10 27.
Article in English | MEDLINE | ID: mdl-29078776

ABSTRACT

BACKGROUND: The Chinese government has long been committed to eliminating the inequality in the utilization of health services; however, it still lacks an analysis or measurement of the economy-related inequality in the utilization of women's health services. METHODS: The economy-related utilization of health services in women aged 15 years and above was assessed by the horizontal inequity index of a two-week outpatient rate and annual inpatient rate from the 5th National Health Service Survey of Shaanxi Province. The concentration index of each factor was decomposed into the contribution of each factor to the economic-related inequality of health service utilization based on the Probit regression model. RESULTS: The horizontal inequity indexes of the two-week outpatient rate was 0.0493, and the horizontal inequity indexes of the annual impatient rate was 0.0869. The contributions of economic status to the two indexes were 190.71% and 115.80%, respectively. Economic status, age, basic medical insurance, educational status, marital status, urban/rural area, and self-rated health were the main impact factors that affected the inequality in women's health services utilization in Shaanxi. CONCLUSIONS: Health service utilization was different between women with different social demographic characteristics, and unequal health service utilization is evident among women in Shaanxi.


Subject(s)
Health Equity/economics , Healthcare Disparities/economics , Poverty Areas , Women's Health Services/statistics & numerical data , Adolescent , Adult , Aged , China , Female , Health Care Surveys , Humans , Middle Aged , Socioeconomic Factors , Young Adult
13.
Hum Cell ; 30(2): 98-105, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28238196

ABSTRACT

Focal adhesion kinase (FAK) functions as a key enzyme in the integrin-mediated adhesion-signalling pathway. Here, we aimed to investigate the effects of FAK on adhesion of human dental pulp (HDP) cells. We transfected lentiviral vectors to silence or overexpress FAK in HDP cells ex vivo. Early cell adhesion, cell survival and focal contacts (FCs)-related proteins (FAK and paxillin) were examined. By using immunofluorescence, the formation of FCs and cytoskeleton was detected, respectively. We found that both adhesion and survival of HDP cells were suppressed by FAK inhibition. However, FAK overexpression slightly inhibited cell adhesion and exhibited no change in cell survival compared with the control. A thick rim of cytoskeleton accumulated and smaller dot-shaped FCs appeared in FAK knockdown cells. Phosphorylation of paxillin (p-paxillin) was inhibited in FAK knockdown cells, verifying that the adhesion was inhibited. Less cytoskeleton and elongated FCs were observed in FAK-overexpressed cells. However, p-paxillin had no significant difference compared with the control. In conclusion, the data suggest that FAK maintains cell adhesion, survival and cytoskeleton formation, but excessive FAK has no positive effects on these aspects.


Subject(s)
Cell Adhesion/genetics , Dental Pulp/cytology , Focal Adhesion Protein-Tyrosine Kinases/physiology , Adolescent , Adult , Cell Adhesion/physiology , Cell Survival/genetics , Cells, Cultured , Cytoskeleton/metabolism , Dental Pulp/metabolism , Humans , Signal Transduction/genetics , Signal Transduction/physiology , Young Adult
14.
BMC Public Health ; 16(1): 1214, 2016 12 01.
Article in English | MEDLINE | ID: mdl-27905918

ABSTRACT

BACKGROUND: Accelerated population ageing brings about unprecedented challenges to the health system in China. This study aimed to measure the prevalence and the income-related inequality of depressive symptoms, and also identify the determinants of depressive symptom inequality among the elderly in China. METHODS: Data were drawn from the second wave of the China Health and Retirement Longitudinal Study (CHARLS). Depressive symptoms were assessed with a 10-item Center for Epidemiologic Studies-Depression Scale (CES-D), which was preselected in CHARLS. The concentration index was used to measure the magnitude of income-related inequality in depressive symptoms. A decomposition analysis, based on the logit model, was employed to quantify the contribution of each determinant to total inequality. RESULTS: More than 32.55% of the elderly in China had depressive symptoms. Women had a higher prevalence of depressive symptoms than men. The overall concentration index of depressive symptoms was -0.0645 among the elderly, indicating that depressive symptoms are more concentrated among the elderly who lived in economically disadvantaged situations, favoring the rich. Income was found to have the largest percentage of contribution to overall inequality, followed by residents' location and educational attainment. CONCLUSION: The prevalence of depressive symptoms in the elderly was considerably high in China. There was also a pro-rich inequality in depressive symptoms amongst elderly Chinese. It is suggested that some form of policy and intervention strategies, such as establishing the urban-rural integrated medical insurance scheme, enhancing the medical assistance system, and promoting health education programs, is required to alleviate inequitable distribution of depressive symptoms.


Subject(s)
Depression/epidemiology , Income/statistics & numerical data , Retirement/psychology , Aged , China/epidemiology , Female , Humans , Logistic Models , Longitudinal Studies , Male , Middle Aged , Prevalence , Rural Population/statistics & numerical data , Social Class , Socioeconomic Factors
15.
FEBS Lett ; 585(7): 1014-20, 2011 Apr 06.
Article in English | MEDLINE | ID: mdl-21371476

ABSTRACT

Glial fibrillary acidic protein (GFAP) is a principal intermediate filament in mature astrocytes of the central nervous system (CNS), and the regulation of GFAP transcription has not been well understood yet. In the present study, we reported paired box 3 protein (Pax3) as a novel regulator of GFAP transcription, which could bind the promoter region of GFAP and down regulate the GFAP level during the serum-induced astrocyte differentiation of neural stem cells (NSCs). Moreover, the overexpression and suppression of Pax3 could inhibit and promote NSC differentiation, respectively. These data suggest that Pax3 negatively regulates GFAP expression during astrocyte differentiation in vitro.


Subject(s)
Astrocytes/cytology , Cell Differentiation/genetics , Down-Regulation , Glial Fibrillary Acidic Protein/genetics , Neural Stem Cells/cytology , Paired Box Transcription Factors/genetics , Animals , Astrocytes/metabolism , Electrophoretic Mobility Shift Assay , HEK293 Cells , Humans , Neural Stem Cells/metabolism , Oligonucleotide Probes/genetics , PAX3 Transcription Factor , Paired Box Transcription Factors/metabolism , Promoter Regions, Genetic/genetics , Rats , Transcription, Genetic
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