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1.
Biomimetics (Basel) ; 9(2)2024 Jan 31.
Article in English | MEDLINE | ID: mdl-38392130

ABSTRACT

Inverse optimal control is a method for recovering the cost function used in an optimal control problem in expert demonstrations. Most studies on inverse optimal control have focused on building the unknown cost function through the linear combination of given features with unknown cost weights, which are generally considered to be constant. However, in many real-world applications, the cost weights may vary over time. In this study, we propose an adaptive online inverse optimal control approach based on a neural-network approximation to address the challenge of recovering time-varying cost weights. We conduct a well-posedness analysis of the problem and suggest a condition for the adaptive goal, under which the weights of the neural network generated to achieve this adaptive goal are unique to the corresponding inverse optimal control problem. Furthermore, we propose an updating law for the weights of the neural network to ensure the stability of the convergence of the solutions. Finally, simulation results for an example linear system are presented to demonstrate the effectiveness of the proposed strategy. The proposed method is applicable to a wide range of problems requiring real-time inverse optimal control calculations.

2.
IEEE J Biomed Health Inform ; 20(5): 1384-96, 2016 09.
Article in English | MEDLINE | ID: mdl-26208372

ABSTRACT

Suicide has been a major cause of death throughout the world. Recent studies have proved a reliable connection between the emotional traits and suicide. However, detection and prevention of suicide are mostly carried out in the clinical centers, which limit the effective treatments to a restricted group of people. To assist detecting suicide risks among the public, we propose a novel method by exploring the accumulated emotional information from people's daily writings (i.e., Blogs), and examining these emotional traits that are predictive of suicidal behaviors. A complex emotion topic model is employed to detect the underlying emotions and emotion-related topics in the Blog streams, based on eight basic emotion categories and five levels of emotion intensities. Since suicide is caused through an accumulative process, we propose three accumulative emotional traits, i.e., accumulation, covariance, and transition of the consecutive Blog emotions, and employ a generalized linear regression algorithm to examine the relationship between emotional traits and suicide risk. Our experiment results suggest that the emotion transition trait turns to be more discriminative of the suicide risk, and that the combination of three traits in linear regression would generate even more discriminative predictions. A classification of the suicide and nonsuicide Blog articles in our additional experiment verifies this result. Finally, we conduct a case study of the most commonly mentioned emotion-related topics in the suicidal Blogs, to further understand the association between emotions and thoughts for these authors.


Subject(s)
Blogging/classification , Emotions/classification , Suicide, Attempted/prevention & control , Suicide, Attempted/statistics & numerical data , Humans , Regression Analysis , Risk
3.
PLoS One ; 9(7): e102039, 2014.
Article in English | MEDLINE | ID: mdl-25036529

ABSTRACT

The wealth of interaction information provided in biomedical articles motivated the implementation of text mining approaches to automatically extract biomedical relations. This paper presents an unsupervised method based on pattern clustering and sentence parsing to deal with biomedical relation extraction. Pattern clustering algorithm is based on Polynomial Kernel method, which identifies interaction words from unlabeled data; these interaction words are then used in relation extraction between entity pairs. Dependency parsing and phrase structure parsing are combined for relation extraction. Based on the semi-supervised KNN algorithm, we extend the proposed unsupervised approach to a semi-supervised approach by combining pattern clustering, dependency parsing and phrase structure parsing rules. We evaluated the approaches on two different tasks: (1) Protein-protein interactions extraction, and (2) Gene-suicide association extraction. The evaluation of task (1) on the benchmark dataset (AImed corpus) showed that our proposed unsupervised approach outperformed three supervised methods. The three supervised methods are rule based, SVM based, and Kernel based separately. The proposed semi-supervised approach is superior to the existing semi-supervised methods. The evaluation on gene-suicide association extraction on a smaller dataset from Genetic Association Database and a larger dataset from publicly available PubMed showed that the proposed unsupervised and semi-supervised methods achieved much higher F-scores than co-occurrence based method.


Subject(s)
Biomedical Research , Data Mining/methods , Natural Language Processing , Publications , Algorithms , Cluster Analysis , Genetic Association Studies , Humans , Pattern Recognition, Automated , Protein Interaction Mapping , PubMed , Suicide
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