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Nanoscale ; 9(32): 11410-11417, 2017 Aug 17.
Article in English | MEDLINE | ID: mdl-28678265

ABSTRACT

Atomic layer deposition on pharmaceutical particles for drug delivery applications is demonstrated using assisted fluidized bed dry powder processing. Complete and conformal layering is achieved on particle sizes from the lower micron to upper nanometer range under near ambient conditions. As few as 2-14 atomic alumina layers alter particle properties: dissolution, dispersibility and heat transfer.


Subject(s)
Drug Carriers/chemical synthesis , Drug Delivery Systems , Particle Size , Powders/chemical synthesis , Aluminum Oxide/chemistry , Budesonide/chemistry , Lactose/chemistry
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