ABSTRACT
Background: Choroid plexus tumors are uncommon neoplasms derived from the neuroepithelium that covers the ventricular cavity and the central canal of the spinal cord that are characterized by papillar aspect and intraventricular growth. It occurs more commonly in dogs, but it has been reported in horses, cows, ferrets and is rare in cats. After the meningiomas and gliomas, choroid plexus tumors are the third encephalic tumors in dogs. In veterinary medicine, there are not many actual reports of this type of neoplasia, therefore, the aim of this paper was to report a case of a choroid plexus papilloma in a poodle dog.Case: A six year old dog, female, poodle, was admitted at the Veterinary Hospital of the São Paulo State University Júlio de Mesquita Filho with a complaint of seizures for 15 days, blindness and head tilt to the right side. At the neurological examination, it had depression, head tilt to the right, circling and ataxia, postural reactions defi cits, absent menace response, absent light pupillary reflex with mydriasis and augmented patellar refl ex. The patient was submitted to blood harvest to perform CBC count and biochemical profi le (renal and hepatic), which were normal. The cerebrospinal fluid analysis presented a discrete raise of proteins. The animal was treated with phenobarbital and prednisone, under suspicion of infl ammatory disease or encephalic neopla
Background: Choroid plexus tumors are uncommon neoplasms derived from the neuroepithelium that covers the ventricular cavity and the central canal of the spinal cord that are characterized by papillar aspect and intraventricular growth. It occurs more commonly in dogs, but it has been reported in horses, cows, ferrets and is rare in cats. After the meningiomas and gliomas, choroid plexus tumors are the third encephalic tumors in dogs. In veterinary medicine, there are not many actual reports of this type of neoplasia, therefore, the aim of this paper was to report a case of a choroid plexus papilloma in a poodle dog.Case: A six year old dog, female, poodle, was admitted at the Veterinary Hospital of the São Paulo State University Júlio de Mesquita Filho with a complaint of seizures for 15 days, blindness and head tilt to the right side. At the neurological examination, it had depression, head tilt to the right, circling and ataxia, postural reactions defi cits, absent menace response, absent light pupillary reflex with mydriasis and augmented patellar refl ex. The patient was submitted to blood harvest to perform CBC count and biochemical profi le (renal and hepatic), which were normal. The cerebrospinal fluid analysis presented a discrete raise of proteins. The animal was treated with phenobarbital and prednisone, under suspicion of infl ammatory disease or encephalic neopla
ABSTRACT
Background: Choroid plexus tumors are uncommon neoplasms derived from the neuroepithelium that covers the ventricular cavity and the central canal of the spinal cord that are characterized by papillar aspect and intraventricular growth. It occurs more commonly in dogs, but it has been reported in horses, cows, ferrets and is rare in cats. After the meningiomas and gliomas, choroid plexus tumors are the third encephalic tumors in dogs. In veterinary medicine, there are not many actual reports of this type of neoplasia, therefore, the aim of this paper was to report a case of a choroid plexus papilloma in a poodle dog.Case: A six year old dog, female, poodle, was admitted at the Veterinary Hospital of the São Paulo State University Júlio de Mesquita Filho with a complaint of seizures for 15 days, blindness and head tilt to the right side. At the neurological examination, it had depression, head tilt to the right, circling and ataxia, postural reactions defi cits, absent menace response, absent light pupillary reflex with mydriasis and augmented patellar refl ex. The patient was submitted to blood harvest to perform CBC count and biochemical profi le (renal and hepatic), which were normal. The cerebrospinal fluid analysis presented a discrete raise of proteins. The animal was treated with phenobarbital and prednisone, under suspicion of infl ammatory disease or encephalic neopla
Background: Choroid plexus tumors are uncommon neoplasms derived from the neuroepithelium that covers the ventricular cavity and the central canal of the spinal cord that are characterized by papillar aspect and intraventricular growth. It occurs more commonly in dogs, but it has been reported in horses, cows, ferrets and is rare in cats. After the meningiomas and gliomas, choroid plexus tumors are the third encephalic tumors in dogs. In veterinary medicine, there are not many actual reports of this type of neoplasia, therefore, the aim of this paper was to report a case of a choroid plexus papilloma in a poodle dog.Case: A six year old dog, female, poodle, was admitted at the Veterinary Hospital of the São Paulo State University Júlio de Mesquita Filho with a complaint of seizures for 15 days, blindness and head tilt to the right side. At the neurological examination, it had depression, head tilt to the right, circling and ataxia, postural reactions defi cits, absent menace response, absent light pupillary reflex with mydriasis and augmented patellar refl ex. The patient was submitted to blood harvest to perform CBC count and biochemical profi le (renal and hepatic), which were normal. The cerebrospinal fluid analysis presented a discrete raise of proteins. The animal was treated with phenobarbital and prednisone, under suspicion of infl ammatory disease or encephalic neopla
ABSTRACT
São descritos os achados anatomopatológicos de um caso de mixossarcoma cutâneo em um Hamster Sírio de 2 anos de idade. Macroscopicamente, foi evidenciada um grande massa cutânea na região cervical lateral direita. A microscopia revelou a presença de um caso de mixossarcoma caracterizado por células fusiformes pleomórficas, frouxamente arranjadas, distribuídas aleatoriamente e, apresentando quantidade moderada de substância basofílica amorfa no estroma e áreas hemorrágicas. O estroma basofílico amorfo foi positivo na coloração Alcian blue, confirmando a presença de matriz mucopolissacarídea. Na imunoistoquímica, as células neoplásicas expressaram vimentina e foram negativas para a marcação de citoqueratina e proteína ácida fibrilar (GFAP).
The pathological findings in a 2-years-old Syrian hamster (Mesocricetus auratus) with a cutaneous myxosarcoma are described. Grossly, there was a large cutaneous mass in the right cervical region. Microscopical evaluation revealed a myxosarcoma characterized by pleomorphic, fusiform cells loosely arranged, randomly distributed, and presenting a moderate amount of basophilic amorphous stroma. There were hemorrhagic areas within the tumor. The basophilic amorphous stroma was positive to Alcian blue confirming the presence of a mucopolysaccharide matrix. Immunohistochemically, the neoplastic cells expressed vimentin, and were negative for cytokeratin or glial fibrillary acidic protein (GFAP).
ABSTRACT
RESUMO A encefalite do cão Pug é uma doença inflamatória idiopática rara do sistema nervoso central, que acomete cães de raças de pequeno porte. Acredita-se que tenha relação com infecções virais e com a presença de anticorpos contra uma substância presente no cérebro, além da predisposição genética e racial. Os sinais clínicos decorrentes desta enfermidade incluem: letargia, ataxia, andar em círculos, déficits proprioceptivos, cegueira e convulsões, dentre outros. O diagnóstico é difícil, sendo geralmente necroscópico, não exististindo tratamento específico para a doença, o que torna o prognóstico ruim. O presente relato descreve o caso de um cão da raça Pug, de um ano de idade, atendido no Hospital Veterinário da UNESP/Botucatu, apresentando apatia, desorientação, sialorréia, dispnéia e um episódio convulsivo. Após parada cardiorrespiratória, o animal veio a óbito, sendo encaminhado à necrópsia, onde pelos achados anatomopatológicos estabeleceu-se o diagnóstico de encefalite do Pug. Palavras-chave: sistema nervoso central, inflamação, histopatologia. PUG DOG ENCEPHALITIS: CASE REPORT ABSTRACT The Pug dog encephalitis is a rare idiopathic inflammatory disease of the central nervous system, which affects dogs from small breeds. It is believed to have relation with viral infections and the presence of antibodies against a substance in the brain, in addition to genetic and
ABSTRACT
RESUMO A encefalite do cão Pug é uma doença inflamatória idiopática rara do sistema nervoso central, que acomete cães de raças de pequeno porte. Acredita-se que tenha relação com infecções virais e com a presença de anticorpos contra uma substância presente no cérebro, além da predisposição genética e racial. Os sinais clínicos decorrentes desta enfermidade incluem: letargia, ataxia, andar em círculos, déficits proprioceptivos, cegueira e convulsões, dentre outros. O diagnóstico é difícil, sendo geralmente necroscópico, não exististindo tratamento específico para a doença, o que torna o prognóstico ruim. O presente relato descreve o caso de um cão da raça Pug, de um ano de idade, atendido no Hospital Veterinário da UNESP/Botucatu, apresentando apatia, desorientação, sialorréia, dispnéia e um episódio convulsivo. Após parada cardiorrespiratória, o animal veio a óbito, sendo encaminhado à necrópsia, onde pelos achados anatomopatológicos estabeleceu-se o diagnóstico de encefalite do Pug. Palavras-chave: sistema nervoso central, inflamação, histopatologia. PUG DOG ENCEPHALITIS: CASE REPORT ABSTRACT The Pug dog encephalitis is a rare idiopathic inflammatory disease of the central nervous system, which affects dogs from small breeds. It is believed to have relation with viral infections and the presence of antibodies against a substance in the brain, in addition to genetic and