Selection of dynamic features based on time-frequency representations for heart murmur detection from phonocardiographic signals.

This work discusses a method for the selection of dynamic features, based on the calculation of the spectral power through time applied to the detection of systolic murmurs from phonocardiographic recordings. To investigate the dynamic properties of the spectral power during murmurs, several quadratic energy distributions have been studied, namely Wigner-Ville, Choi-Williams, smoothed pseudo Wigner-Ville, exponential, and hyperbolic T-distribution. The classification performance has been compared with that using a Short Time Fourier Transform and Continuous Wavelet Transform representations. Furthermore, this work discusses a variety of nonparametric techniques to estimate the spectral power contours as dynamic features that characterize the heart sounds (HS): instantaneous energy, eigenvectors, instantaneous frequency, equivalent bandwidth, subband spectral centroids, and Mel cepstral coefficients. In this way, the aforementioned time-frequency representations and their dynamic features were evaluated by means of their ability to detect the presence of murmurs using a simple k-Nearest Neighbors classifier. Moreover, the relevancies of the proposed dynamic features have been evaluated using a time-varying principal component analysis. The work presented is carried out using a database containing 22 phonocardiographic recordings (16 normal and 6 records with murmurs), segmented to extract 402 representative individual beats (201 per class). The results suggest that the smoothing given by the quadratic energy distribution significantly improves the classification performance for the detection of murmurs in HS. Moreover, it is shown that the power dynamic features which give the best overall classification performance are the MFCC contours. As a result, the proposed method can be implemented as a simple diagnostic tool for primary health-care purposes with high accuracy (up to 98%) discriminating between normal and pathologic beats.

Detection of obstructive sleep apnea in ECG recordings using time-frequency distributions and dynamic features.

Detection of obstructive sleep apnea can be performed through heart rate variability analysis, since fluctuations of oxygen saturation in blood cause variations in the heart rate. Such variations in heart rate can be assessed by means of time-frequency analysis implemented with time-frequency distributions belonging to Cohen's class. In this work, dynamic features are extracted from time frequency distributions in order to detect obstructive sleep apnea from ECG signals recorded during sleep. Furthermore, it is applied a methodology to measure the relevance of each dynamic feature, before the implementation of k-nn classifier used to recognize the normal and pathologic signals. As a result, the proposed method can be applied as a simple diagnostic tool for OSA with a high accuracy (up to 92.67%) in one-minute intervals.

Digital auscultation analysis for heart murmur detection.

This work presents a comparison of different approaches for the detection of murmurs from phonocardiographic signals. Taking into account the variability of the phonocardiographic signals induced by valve disorders, three families of features were analyzed: (a) time-varying & time-frequency features; (b) perceptual; and (c) fractal features. With the aim of improving the performance of the system, the accuracy of the system was tested using several combinations of the aforementioned families of parameters. In the second stage, the main components extracted from each family were combined together with the goal of improving the accuracy of the system. The contribution of each family of features extracted was evaluated by means of a simple k-nearest neighbors classifier, showing that fractal features provide the best accuracy (97.17%), followed by time-varying & time-frequency (95.28%), and perceptual features (88.7%). However, an accuracy around 94% can be reached just by using the two main features of the fractal family; therefore, considering the difficulties related to the automatic intrabeat segmentation needed for spectral and perceptual features, this scheme becomes an interesting alternative. The conclusion is that fractal type features were the most robust family of parameters (in the sense of accuracy vs. computational load) for the automatic detection of murmurs. This work was carried out using a database that contains 164 phonocardiographic recordings (81 normal and 83 records with murmurs). The database was segmented to extract 360 representative individual beats (180 per class).

Feature extraction for murmur detection based on support vector regression of time-frequency representations.

This paper presents a nonlinear approach for time-frequency representations (TFR) data analysis, based on a statistical learning methodology - support vector regression (SVR), that being a nonlinear framework, matches recent findings on the underlying dynamics of cardiac mechanic activity and phonocardiographic (PCG) recordings. The proposed methodology aims to model the estimated TFRs, and extract relevant features to perform classification between normal and pathologic PCG recordings (with murmur). Modeling of TFR is done by means of SVR, and the distance between regressions is calculated through dissimilarity measures based on dot product. Finally, a k-nn classifier is used for the classification stage, obtaining a validation performance of 97.85%.