Staphylococcus aureus in the nose and throat of Iowan families.

The study objective was to determine the prevalence of Staphylococcus aureus colonisation in the nares and oropharynx of healthy persons and identify any risk factors associated with such S. aureus colonisation. In total 263 participants (177 adults and 86 minors) comprising 95 families were enrolled in a year-long prospective cohort study from one urban and one rural county in eastern Iowa, USA, through local newspaper advertisements and email lists and through the Keokuk Rural Health Study. Potential risk factors including demographic factors, medical history, farming and healthcare exposure were assessed. Among the participants, 25.4% of adults and 36.1% minors carried S. aureus in their nares and 37.9% of adults carried it in their oropharynx. The overall prevalence was 44.1% among adults and 36.1% for minors. Having at least one positive environmental site for S. aureus in the family home was associated with colonisation (prevalence ratio: 1.34, 95% CI: 1.07-1.66). The sensitivity of the oropharyngeal cultures was greater than that of the nares cultures (86.1% compared with 58.2%, respectively). In conclusion, the nares and oropharynx are both important colonisation sites for healthy community members and the presence of S. aureus in the home environment is associated with an increased probability of colonisation.

Delta-sigma oversampled ultrasound beamformer with dynamic delays.

The principles of oversampling are exploited in a simple beamforming architecture using a single bit delta-sigma (DeltaC) analog to digital converter (A/D) on every channel. The high sampling rate required for the single bit A/D provides adequate delay accuracy for high quality beamforming using elementary sample manipulations. Images produced with this beamformer exhibit significant artifacts directly related to dynamic focusing. However, a simple digital recording technique following delays permits dynamically focused beamforming without degrading image quality. The simplicity of this beamformer compared to conventional methods may facilitate very large channel count or low power beamformers suitable for 1.5-D arrays or portable scanners.

Heterodyning technique to improve performance of delta-sigma-based beamformers.

Delta-sigma (DeltaSigma) modulators can implement a simpler digital ultrasound beamformer than can traditional architectures based on multi-bit analog-to-digital converters (A/D). The signal-to-noise ratio (SNR) of the DeltaSigma modulators, however, suffers from limited oversampling ratios. To improve the SNR of each channel, a mixing signal heterodynes narrowband signals to lower frequencies where the baseband DeltaSigma modulator performs better. Noise figure analyses are presented that illustrate the effectiveness of this technique in improving noise performance. Also, spectral Doppler and color flow simulations are presented that realistically emulate a 32 channel oversampled beamformer and compare these results with traditional and ideal systems.