ABSTRACT
Calcinosis cutis (CC) is defined as the deposition of calcium salts on the skin and subcutaneous tissue. It is associated with different conditions, including some autoimmune diseases, and it can generate significant inflammation, pain, and functional impairment. Different therapies have been tried with limited results. Intralesional sodium thiosulfate seems a promising therapeutic option. We report a patient with diffuse systemic sclerosis who presented with two symmetrical plaques on both axillae, which caused pain and skin retraction. The clinical diagnosis was consistent with CC, which was confirmed by skin biopsy and ultrasound. The patient was treated with a 250 mg/ml solution of sodium thiosulfate injected into the plaques. Complete resolution was achieved after three monthly sessions. The only reported adverse effect was a transient burning sensation during the injections. Given its effectiveness and safety, we believe that intralesional sodium thiosulfate could become a valid first-line option for the treatment of CC.
Subject(s)
Calcinosis , Scleroderma, Systemic , Skin Diseases , Calcinosis/diagnostic imaging , Calcinosis/drug therapy , Humans , Scleroderma, Systemic/complications , Scleroderma, Systemic/drug therapy , Skin Diseases/drug therapy , ThiosulfatesABSTRACT
No disponible
Subject(s)
Humans , Alopecia/drug therapy , Mesotherapy/methods , Dutasteride/administration & dosage , 5-alpha Reductase Inhibitors/administration & dosage , MicroinjectionsSubject(s)
Mesotherapy , Alopecia/drug therapy , Dutasteride/therapeutic use , Finasteride/therapeutic use , HumansABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Aged , Ear Cartilage/pathology , Diltiazem/therapeutic use , Cartilage Diseases/diagnosis , Ear Cartilage/drug effects , Administration, Topical , Cartilage Diseases/drug therapySubject(s)
Calcium Channel Blockers/administration & dosage , Cartilage Diseases/drug therapy , Dermatitis/drug therapy , Diltiazem/administration & dosage , Ear Diseases/drug therapy , Administration, Topical , Aged , Cartilage Diseases/complications , Dermatitis/complications , Ear Auricle , Ear Diseases/complications , Humans , Male , Middle AgedABSTRACT
No disponible
Subject(s)
Humans , Hyperhidrosis/drug therapy , Botulinum Toxins/administration & dosage , Nerve Block/methods , Hand/physiopathology , Wrist/innervationABSTRACT
La fistula cutánea odontogénica (FCO) es el resultado de una canalización anormal originada a partir de una infección crónica periapical. Representa todo un reto diagnóstico ya que frecuentemente son lesiones etiquetadas erróneamente como dermatológicas. El diagnóstico diferencial es amplio, incluyendo el granuloma piogénico, tuberculosis cutánea o malformaciones congénitas entre otros. Exponemos el caso de un varón de 46 años diagnosticado de FCO que presentó una rápida mejoría tras exodoncia de las piezas dentales afectas y fistulectomía. Consideramos importante el conocimiento de esta patología para evitar retrasos innecesarios en el diagnóstico y tratamiento adecuado (AU)
Odontogenic cutaneous fistula (OCF) is the result of an abnormal canalization originating from chronic periapical infection. It represents a diagnostic challenge, as it is frequently misdiagnosed as dermatological lesion. There is a broad differential diagnosis, including pyogenic granuloma, cutaneous tuberculosis or congenital malformations, among others. We report the case of a 46-year-old man diagnosed with OCF who presented a rapid improvement after extraction of the affected dental pieces and fistulectomy. We consider knowledge of this pathology to be important in order to avoid unnecessary delays in diagnosis and proper treatment (AU)
Subject(s)
Humans , Male , Middle Aged , Dental Fistula/diagnosis , Cutaneous Fistula/diagnosis , Tooth Extraction , Diagnosis, Differential , Radiography, Panoramic , Periapical Abscess/complications , Dental Pulp Necrosis/complicationsABSTRACT
Odontogenic cutaneous fistula (OCF) is the result of an abnormal canalization originating from chronic periapical infection. It represents a diagnostic challenge, as it is frequently misdiagnosed as dermatological lesion. There is a broad differential diagnosis, including pyogenic granuloma, cutaneous tuberculosis or congenital malformations, among others. We report the case of a 46-year-old man diagnosed with OCF who presented a rapid improvement after extraction of the affected dental pieces and fistulectomy. We consider knowledge of this pathology to be important in order to avoid unnecessary delays in diagnosis and proper treatment. Key words. Cutaneous fistula. DIAGNOSIS: Orthopantomography.
Subject(s)
Cutaneous Fistula/diagnosis , Cutaneous Fistula/etiology , Periapical Diseases/complications , Humans , Male , Middle Aged , Periapical Diseases/microbiologyABSTRACT
No disponible
Subject(s)
Humans , Dermatitis, Seborrheic/drug therapy , Itraconazole/therapeutic use , Patient Safety , Treatment OutcomeABSTRACT
Frontal fibrosing alopecia (FFA) is a scarring alopecia whose incidence is increasing significantly in our country. It is characterized by loss of frontotemporal hairline that mostly affects postmenopausal women, with a negative impact on quality of life. It is associated with early menopause in 14% of cases and hypothyroidism in 15%. With regard to treatment, 5α-reductase inhibitors are the drugs that have shown improvement of the disease in a larger number of cases. We report a new case of FFA in a woman of 77 years successfully treated with finasteride at doses of 2.5mg daily.
Subject(s)
Alopecia , 5-alpha Reductase Inhibitors/therapeutic use , Aged , Alopecia/drug therapy , Alopecia/epidemiology , Female , Finasteride/therapeutic use , Humans , Remission InductionABSTRACT
La alopecia frontal fibrosante (AFF) es un tipo de alopecia cicatricial cuya incidencia está aumentando de forma significativa en nuestro país. Se caracteriza por un retroceso en la línea de implantación del pelo a nivel frontotemporal que afecta mayoritariamente a mujeres postmenopaúsicas, con un impacto negativo en su calidad de vida. Se asocia a menopausia precoz en un 14% de los casos y a hipotiroidismo en un 15%. Con respecto al tratamiento, son los inhibidores de la 5α-reductasa, los fármacos que han demostrado mejoría de la enfermedad en un mayor número de casos. Presentamos un caso de AFF en una mujer de 77 años tratada con éxito con finasteride a dosis de 2,5mg/día (AU)
Frontal fibrosing alopecia (FFA) is a scarring alopecia whose incidence is increasing significantly in our country. It is characterized by loss of frontotemporal hairline that mostly affects postmenopausal women, with a negative impact on quality of life. It is associated with early menopause in 14% of cases and hypothyroidism in 15%. With regard to treatment, 5α-reductase inhibitors are the drugs that have shown improvement of the disease in a larger number of cases. We report a new case of FFA in a woman of 77 years successfully treated with finasteride at doses of 2.5mg daily (AU)
Subject(s)
Humans , Female , Aged , Alopecia/complications , Alopecia/drug therapy , Finasteride/therapeutic use , Adrenal Cortex Hormones/therapeutic use , 5-alpha Reductase Inhibitors/therapeutic use , Pruritus/complications , Pruritus/therapyABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Stevens-Johnson Syndrome/epidemiology , Stevens-Johnson Syndrome/mortality , Stevens-Johnson Syndrome/therapy , Necrosis/complications , Necrosis/therapy , Cyclosporine/pharmacology , Cyclosporine/therapeutic use , Etanercept/pharmacology , Etanercept/therapeutic use , Cyclophosphamide/pharmacology , Cyclophosphamide/therapeutic use , Adrenal Cortex Hormones/pharmacology , Adrenal Cortex Hormones/therapeutic use , Immunoglobulins, Intravenous/therapeutic useABSTRACT
No disponible
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Telangiectasia, Hereditary Hemorrhagic/diagnosis , Telangiectasia, Hereditary Hemorrhagic/epidemiology , Telangiectasia, Hereditary Hemorrhagic/prevention & control , Laser Therapy/instrumentation , Laser Therapy/methods , Laser Therapy , Skin Diseases/prevention & control , Skin Diseases/therapySubject(s)
Laser Therapy , Lasers, Solid-State , Telangiectasia, Hereditary Hemorrhagic/surgery , Adult , Aged , Female , Humans , Male , Middle Aged , RecurrenceABSTRACT
No disponible
