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1.
Article in English | MEDLINE | ID: mdl-38632016

ABSTRACT

BACKGROUND: The calculation of body height in the intensive care unit is essential for obtaining the ideal body weight, which is used to program the tidal volume and establish objective and effective pulmonary ventilation. The objective of the study was to determine the interrater reliability of a tool for measuring body height in adult patients in an intensive care unit (ICU) in southwestern Colombia. METHODS: This cross-sectional observational study was conducted between January and May 2021, following the recommendations of the COSMIN protocol. Two physiotherapists in the roles of observer/evaluator measured the heights of 106 patients upon admission to the ICU with a previously designed. The sample size was calculated based on Pearson's correlation coefficient. For interrater reliability, the intraclass correlation coefficient (ICC) was used, and Bland-Altman analysis was used to assess concordance. The 95% confidence interval was established, and a P value <0.05 indicated statistical significance. RESULTS: A total of 106 individuals with a mean age of 59.3 years were included; the mean body height was 158.5 cm for women. The interrater reliability of the measurement of height was excellent (global ICC of 0.99, P = 0.000), and an almost perfect positive correlation was obtained between the raters for both women and men (R = 0.99). CONCLUSIONS: Excellent interrater/interobserver reliability was obtained for the measurement of body height in the ICU. This research highlights the importance of protocolizing the measurement of height in critical patients with valid and reliable instruments.

2.
Neurología (Barc., Ed. impr.) ; 38(9): 617-624, Nov-Dic. 2023. tab, graf
Article in English | IBECS | ID: ibc-227345

ABSTRACT

Introduction: Despite the highly favorable prognosis, mortality occurs in nearly 2% of patients with cerebral venous thrombosis (CVT), in which decompressive craniectomy (DC) may be the only way to save the patient's life. The aim of this report is to describe the risk factors, neuroimaging features, in-hospital complications and functional outcome of severe CVT in patients treated with DC. Materials and methods: Consecutive malignant CVT cases treated with DC from a retrospective third-level hospital database were analyzed. Demographic, clinical, and functional outcomes were analyzed. Results: Twenty-six patients were included (20 female, age 35.4 ± 12.1 years); 53.8% of the patients had acute CVT, with neurological focalization as the most common symptom in 92.3% of the patients. Superior sagittal sinus thromboses were found in 84.6% of cases. Bilateral lesions were present in 10 patients (38.5%). Imaging on admission showed a parenchymal lesion (venous infarction ± hemorrhagic lesion) > 6 cm measured along the longest diameter in 25 patients (96.2%). Mean duration of clinical neurological deterioration was 3.5 days; eleven patients (42.3%) died during hospitalization. Conclusion: In patients with severe forms of CVT, we found higher mortality than previously reported. DC is an effective life-saving treatment with acceptable functional prognosis for survivors.(AU)


Introducción: A pesar del pronóstico favorable en pacientes con trombosis venosa cerebral (TVC), cerca de un 2% de estos pacientes fallecen, para los cuales la craniectomía descompresiva (CD) puede ser una opción terapéutica. El objetivo de este artículo es describir los factores de riesgo, las características de las neuroimágenes, complicaciones hospitalarias y evolución funcional, de pacientes con TVC severa tratados con CD. Materiales y métodos: Se analizaron características demográficas, clínicas y funcionales de casos consecutivos de TVC severa tratados con CD, a partir de una base de datos retrospectiva de un hospital de tercer nivel. Resultados: Veintiséis pacientes fueron incluidos (20 mujeres, media de edad 35,4 ±12,1 años); un 53,8% de los pacientes presentaron una TVC aguda, con manifestaciones neurológicas focales como el síntoma más frecuente en el 92,3% de los casos. La trombosis del seno sagital superior estuvo presente en el 84,6% y se presentaron lesiones bilaterales parenquimatosas en 10 pacientes (38,5%). La imagen al ingreso demostró lesiones parenquimatosas (infarto venoso ± lesión hemorrágica) > 6 cm (medida en el mayor diámetro de la misma), en 25 pacientes (96,2%). La duración media del deterioro neurológico fue de 3,5 días; 11 pacientes (42,3%) murieron durante la hospitalización. Conclusión: En pacientes con formas severas de TVC encontramos una mayor mortalidad que la publicada previamente; la CD podría ser una opción terapéutica en ese grupo de pacientes.(AU)


Subject(s)
Humans , Female , Adult , Venous Thrombosis , Decompressive Craniectomy , Neuroimaging/methods , Mortality , Neurology , Nervous System Diseases , Risk Factors , Retrospective Studies
3.
Neurologia (Engl Ed) ; 38(9): 617-624, 2023.
Article in English | MEDLINE | ID: mdl-37996212

ABSTRACT

INTRODUCTION: Despite the highly favorable prognosis, mortality occurs in nearly 2% of patients with cerebral venous thrombosis (CVT), in which decompressive craniectomy (DC) may be the only way to save the patient's life. The aim of this report is to describe the risk factors, neuroimaging features, in-hospital complications and functional outcome of severe CVT in patients treated with DC. MATERIALS AND METHODS: Consecutive malignant CVT cases treated with DC from a retrospective third-level hospital database were analyzed. Demographic, clinical, and functional outcomes were analyzed. RESULTS: Twenty-six patients were included (20 female, age 35.4±12.1 years); 53.8% of the patients had acute CVT, with neurological focalization as the most common symptom in 92.3% of the patients. Superior sagittal sinus thromboses were found in 84.6% of cases. Bilateral lesions were present in 10 patients (38.5%). Imaging on admission showed a parenchymal lesion (venous infarction±hemorrhagic lesion)>6cm measured along the longest diameter in 25 patients (96.2%). Mean duration of clinical neurological deterioration was 3.5 days; eleven patients (42.3%) died during hospitalization. CONCLUSION: In patients with severe forms of CVT, we found higher mortality than previously reported. DC is an effective life-saving treatment with acceptable functional prognosis for survivors.


Subject(s)
Decompressive Craniectomy , Venous Thrombosis , Humans , Female , Young Adult , Adult , Middle Aged , Decompressive Craniectomy/methods , Retrospective Studies , Prognosis , Treatment Outcome , Venous Thrombosis/surgery , Venous Thrombosis/complications , Venous Thrombosis/diagnosis
4.
Eur Rev Med Pharmacol Sci ; 27(16): 7738-7748, 2023 08.
Article in English | MEDLINE | ID: mdl-37667952

ABSTRACT

OBJECTIVE: The aim of this study was to develop an initial valid tool to measure attitudes toward cancer-related cognitive changes. SUBJECTS AND METHODS: After revising the literature, three main dimensions were hypothesized. Eight judges were contacted to obtain content validity evidence. A robust Exploratory Factor Analysis (EFA) was performed via a parallel analysis with an Unweighted Least Squares (ULS) estimator and polychoric correlations. The results were crossed with sociodemographic variables to find possible statistical differences and estimate the size effect. Analysis was performed in the software Factor and the statistical package R. RESULTS: A sample of 374 participants was obtained, involving oncology patients, their caregivers, and people from the general community. A statistical fit was found in two dimensions: Awareness and Judgments [root mean squared error of approximation (RMSEA) = 0.042, standardized root mean square residual (SRMR) = 0.02, comparative fit index (CFI) = 0.99, Tucker-Lewis index (TLI) = 0.98] with a moderate correlation between them (r = 0.612). Optimal reliability indices were obtained for the total scale and its dimensions. No real statistical difference was found between sociodemographic variables; the interpretation norms were established via the quartiles. CONCLUSIONS: The first attempt to measure the construct of interest was developed with two primary validity evidence based on the content and its internal structure. This instrument could help strengthen the prevention of cancer-related cognitive changes. More research is needed to adhere more valid evidence to the scale.


Subject(s)
Medical Oncology , Neoplasms , Humans , Colombia , Reproducibility of Results , Software , Cognition
5.
Hipertens. riesgo vasc ; 40(3): 132-136, jul.-sep. 2023. tab
Article in Spanish | IBECS | ID: ibc-226275

ABSTRACT

La hipertensión arterial (HTA) es una dolencia frecuente en los pacientes con neoplasias oncohematológicas activas o supervivientes a estas. Se estima que la prevalencia de HTA en esta población oscila entre el 30 y el 70%. La relación entre cáncer e HTA es multifactorial: factores de riesgo comunes, neoplasias que producen HTA a través de la secreción hormonal y, especialmente, fármacos quimioterápicos que producen HTA. La monitorización ambulatoria de presión arterial (MAPA) es una herramienta fundamental en el diagnóstico y adecuado control de la presión arterial, evitando tener que suspender o disminuir la dosis de tratamiento quimioterápico. Además, puede ayudar en el diagnóstico de la disfunción autonómica relacionada con ciertas enfermedades neoplásicas. (AU)


Hypertension (HT) is a frequent pathology in patients with active or surviving onco-haematological malignancies. It is estimated that the prevalence of HT in this population ranges between 30 and 70%. The relationship between cancer and HT is multifactorial: common risk factors, neoplasia that cause HT through hormonal secretion, and, especially, chemotherapy drugs that cause HT. Ambulatory blood pressure monitoring (ABPM) is a fundamental tool in the diagnosis and adequate control of blood pressure, avoiding having to suspend or reduce the dose of chemotherapy treatment. In addition, it can help in the diagnosis of autonomic dysfunction related to certain neoplastic pathologies. (AU)


Subject(s)
Humans , Hypertension/epidemiology , Neoplasms , Medical Oncology , Blood Pressure Monitoring, Ambulatory , Hypertension/diagnosis , Hypertension/prevention & control , Risk Factors
6.
Hipertens. riesgo vasc ; 40(3): 145-149, jul.-sep. 2023. graf, ilus
Article in Spanish | IBECS | ID: ibc-226277

ABSTRACT

Los inhibidores de la tirosinacinasa son una familia de fármacos quimioterápicos utilizados en primera y segunda línea de muchas neoplasias sólidas y hematológicas. Su toxicidad es relativamente baja, ya que el mecanismo de acción se fundamenta en la inhibición de algunas tirosinacinasas involucradas en la proliferación de las células neoplásicas. Sin embargo, este bloqueo no es selectivo, por lo que pueden producir efectos secundarios. Sorafenib se ha relacionado con la aparición de hipertensión arterial, alteraciones tiroideas, dolor abdominal o hiperamilasemia, entre otros. Deben conocerse los efectos secundarios de estos fármacos para una adecuada monitorización de los pacientes que evite la suspensión de estos agentes quimioterápicos. (AU)


Tyrosine kinase inhibitors are a family of chemotherapy drugs used in first and second line for many solid and hematological neoplasms. Its toxicity is relatively low, since the mechanism of action is based on the inhibition of some tyrosine kinases involved in the explosion of neoplastic cells. However, this blockade is not selective, so it can produce secondary effects. Sorafenib can produce arterial hypertension, thyroid disorders, abdominal pain or hyperamylasemia, among others. We must monitor these patients during treatment to avoid side effects. (AU)


Subject(s)
Humans , Male , Middle Aged , Sorafenib/poisoning , Sorafenib/therapeutic use , Protein Kinase Inhibitors , Sorafenib/adverse effects , Hypertension , Hypothyroidism , Drug-Related Side Effects and Adverse Reactions
7.
Hipertens Riesgo Vasc ; 40(3): 132-136, 2023.
Article in Spanish | MEDLINE | ID: mdl-37302940

ABSTRACT

Hypertension (HT) is a frequent pathology in patients with active or surviving onco-haematological malignancies. It is estimated that the prevalence of HT in this population ranges between 30 and 70%. The relationship between cancer and HT is multifactorial: common risk factors, neoplasia that cause HT through hormonal secretion, and, especially, chemotherapy drugs that cause HT. Ambulatory blood pressure monitoring (ABPM) is a fundamental tool in the diagnosis and adequate control of blood pressure, avoiding having to suspend or reduce the dose of chemotherapy treatment. In addition, it can help in the diagnosis of autonomic dysfunction related to certain neoplastic pathologies.


Subject(s)
Hematologic Diseases , Hypertension , Humans , Blood Pressure Monitoring, Ambulatory , Hypertension/drug therapy , Blood Pressure , Risk Factors
8.
Hipertens Riesgo Vasc ; 40(3): 145-149, 2023.
Article in Spanish | MEDLINE | ID: mdl-35718693

ABSTRACT

Tyrosine kinase inhibitors are a family of chemotherapy drugs used in first and second line for many solid and hematological neoplasms. Its toxicity is relatively low, since the mechanism of action is based on the inhibition of some tyrosine kinases involved in the explosion of neoplastic cells. However, this blockade is not selective, so it can produce secondary effects. Sorafenib can produce arterial hypertension, thyroid disorders, abdominal pain or hyperamylasemia, among others. We must monitor these patients during treatment to avoid side effects.

9.
Hipertens. riesgo vasc ; 39(1): 46-48, ene-mar 2022. ilus
Article in English | IBECS | ID: ibc-203951

ABSTRACT

Secondary arterial hypertension (HTN) can be caused by primary hyperaldosteronism, renovascular disease, sleep apnea syndrome, chronic kidney disease, drug use, etc. In addition, some urological disorders such as hydronephrosis can cause hypertension due to an increase in intraglomerular pressure that activates the renin angiotensin system.(AU)


La hipertensión arterial (HTA) secundaria engloba un amplio diagnóstico diferencial que incluye causas tan distintas como el hiperaldosteronismo primario, la enfermedad renovascular, el síndrome de apnea del sueño, la enfermedad renal crónica, el consumo de fármacos, etc. Existen, además, ciertos trastornos urológicos como la hidronefrosis que pueden producir HTA debido a un aumento de presión intraglomerular que active el sistema renina-angiotensina.(AU)


Subject(s)
Humans , Female , Adult , Hypertension , Ureterocele , Hydronephrosis , Hyperaldosteronism
10.
Hipertens Riesgo Vasc ; 39(1): 46-48, 2022.
Article in English | MEDLINE | ID: mdl-34400099

ABSTRACT

Secondary arterial hypertension (HTN) can be caused by primary hyperaldosteronism, renovascular disease, sleep apnea syndrome, chronic kidney disease, drug use, etc. In addition, some urological disorders such as hydronephrosis can cause hypertension due to an increase in intraglomerular pressure that activates the renin angiotensin system.


Subject(s)
Hyperaldosteronism , Hypertension , Kidney Diseases , Female , Humans , Hyperaldosteronism/complications , Hypertension/complications , Middle Aged , Renin , Renin-Angiotensin System
11.
Hipertens. riesgo vasc ; 38(3): 151-155, jul.-sep. 2021. tab
Article in Spanish | IBECS | ID: ibc-221312

ABSTRACT

La mejora de la supervivencia de los pacientes con cáncer ha llevado consigo un incremento en la aparición de enfermedad cardiovascular (ECV). Esto es debido al aumento de la edad de los sujetos y a los efectos secundarios de los agentes antineoplásicos. La aparición de hipertensión arterial (HTA) en los pacientes tratados con fármacos anti-angiogénicos es un efecto adverso común, que puede obligar a reducir la dosis de quimioterapia o incluso a suspenderla. Presentamos los casos de tres personas tratadas con distintos anti-angiogénicos, y que desarrollaron HTA secundaria. (AU)


Survival of neoplasms has improved significantly in recent years. An increase in the incidence of cardiovascular disease has been observed. This is due to increasing age of patients and the side effects of chemotherapy. Anti-angiogenic drugs frequently cause hypertension. This may force the reduction or suspension of chemotherapy treatment. We present the cases of three patients treated with different anti-angiogenic drugs. All three developed secondary arterial hypertension. (AU)


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Hypertension/chemically induced , Hypertension/drug therapy , Neoplasms/complications , Neoplasms/drug therapy , Cardiovascular Diseases , Angiogenesis Inhibitors/adverse effects
12.
Neurologia (Engl Ed) ; 2021 Jul 09.
Article in English, Spanish | MEDLINE | ID: mdl-34253412

ABSTRACT

INTRODUCTION: Despite the highly favorable prognosis, mortality occurs in nearly 2% of patients with cerebral venous thrombosis (CVT), in which decompressive craniectomy (DC) may be the only way to save the patient's life. The aim of this report is to describe the risk factors, neuroimaging features, in-hospital complications and functional outcome of severe CVT in patients treated with DC. MATERIALS AND METHODS: Consecutive malignant CVT cases treated with DC from a retrospective third-level hospital database were analyzed. Demographic, clinical, and functional outcomes were analyzed. RESULTS: Twenty-six patients were included (20 female, age 35.4±12.1 years); 53.8% of the patients had acute CVT, with neurological focalization as the most common symptom in 92.3% of the patients. Superior sagittal sinus thromboses were found in 84.6% of cases. Bilateral lesions were present in 10 patients (38.5%). Imaging on admission showed a parenchymal lesion (venous infarction±hemorrhagic lesion)>6cm measured along the longest diameter in 25 patients (96.2%). Mean duration of clinical neurological deterioration was 3.5 days; eleven patients (42.3%) died during hospitalization. CONCLUSION: In patients with severe forms of CVT, we found higher mortality than previously reported. DC is an effective life-saving treatment with acceptable functional prognosis for survivors.

13.
Hipertens Riesgo Vasc ; 38(3): 151-155, 2021.
Article in Spanish | MEDLINE | ID: mdl-33706996

ABSTRACT

Survival of neoplasms has improved significantly in recent years. An increase in the incidence of cardiovascular disease has been observed. This is due to increasing age of patients and the side effects of chemotherapy. Anti-angiogenic drugs frequently cause hypertension. This may force the reduction or suspension of chemotherapy treatment. We present the cases of three patients treated with different anti-angiogenic drugs. All three developed secondary arterial hypertension.


Subject(s)
Angiogenesis Inhibitors , Cardiovascular Diseases , Hypertension , Neoplasms , Angiogenesis Inhibitors/adverse effects , Humans , Hypertension/chemically induced , Hypertension/drug therapy , Neoplasms/complications , Neoplasms/drug therapy
14.
Tech Coloproctol ; 25(4): 481-482, 2021 04.
Article in English | MEDLINE | ID: mdl-33387101

Subject(s)
Carcinoma , Proctectomy , Colon , Humans , Rectum
15.
Rev Colomb Enferm ; 20(1): e031, 2021.
Article in Spanish | LILACS, BDENF - Nursing, COLNAL | ID: biblio-1253268

ABSTRACT

Introducción: el proceso de parto representa una de las experiencias más importantes para la mujer, puede ser una de las mejores vivencias o el evento más traumático y doloroso que podría tener durante la vida; implica una experiencia psicosocial profunda que pone a prueba su feminidad y competencias personales. Objetivo: describir la percepción de la gestante acerca del cuidado brindado por el profesional en enfermería durante el trabajo de parto en un hospital de nivel III-IV de la ciudad de Neiva, Colombia desde las cinco dimensiones propuestas en la teoría de los cuidados de Kristen Swanson. Métodos: se utilizó la fenomenología interpretativa, y como técnica de recolección de datos la entrevista en profundidad. La muestra se determinó por saturación de la información. Se entrevistaron seis mujeres que tuvieron trabajo de parto, a cada una se le realizaron tres entrevistas, transcritas por las investigadoras. Resultados: se identificaron cinco categorías: 1) El acompañamiento marca la diferencia en el cuidado de enfermería; 2) Lo que necesita la parturienta: confianza, seguridad y tranquilidad; 3) Encontrar un ángel; 4) La enfermera me animaba para seguir adelante; 5) El conocimiento de la enfermera produce seguridad en la gestante. Fue posible determinar que cuando la gestante se sintió acompañada, estableció empatía con la enfermera y, logró sentir confianza, tranquilidad y seguridad. Esto permitió tener una relación de reciprocidad. Además las participantes destacaron que la enfermera se esforzó para otorgar un cuidado más cercano y centrado en la persona. Conclusiones: el cuidado que brinda la enfermera significa algo más que intervenciones asistenciales competentes; implica crear empatía, generar confianza, tranquilidad, seguridad, todo lo cual es propiciado por el acompañamiento que se da a la gestante. (AU)


Introduction: The childbirth process represents one of the most important experiences for a woman. It can be one of the best experiences or the most traumatic and painful event a woman could undergo during her life; it is a deep psychosocial experience that tests her femininity and personal competencies. Objective: To describe pregnant women's perception of the care provided during labor by professional nurses in a Level III-IV hospital in the city of Neiva, Colombia, based on the five processes proposed in Kristen Swanson's theory of caring. Methods: An interpretative phenomenological analysis was used. In-depth interviews were employed as the method of data collection. The sample was determined by data saturation. Six women who were in labor were interviewed; three interviews were conducted with each woman and transcribed by the researchers. Results: Five categories were identified: 1) assistance makes the difference in nursing care, 2) what a woman in labor needs: confidence, security, and peace of mind, 3) finding an angel, 4) the nurse encouraged me to keep going, and 5) nurse's knowledge provides pregnant women with security. It was possible to determine that when the pregnant woman felt assisted, she empathized with the nurse and was able to feel confidence, peace of mind, and security; this allowed for a reciprocal relationship. In addition, the participants highlighted that the nurse made an effort to provide closer and more person-centered care. Conclusions: Nurse-delivered care means something more than competent assistance interventions; it implies developing empathy and building confidence, peace of mind, security, all of which are propitiated by the assistance given to pregnant women. (AU)


Introdução: O processo de parto representa uma das experiências mais importantes nas mulheres e pode ser uma das melhores experiências ou o evento mais traumático e doloroso que poderia ter durante a vida; implicando uma profunda experiência psicossocial que testa sua feminilidade e habilidades pessoais. Esta pesquisa é guiada pela teoria de médio alcance proposta por Kristen Swanson, com seus cinco processos que se sobrepõem e são melhor compreendidos como dimensões de um fenômeno que não são excluídos um do outro, mas podem ser organizados hierarquicamente, conservando a Ideia de uma totalidade. Objetivo: Descrever a percepção da gestante sobre os cuidados prestados pelo profissional de enfermagem durante o trabalho de parto em um hospital do nível III-IV da cidade de Neiva, a partir das cinco dimensões propostas na Teoria do Cuidado de Kristen Swanson. Métodos: Fo i utilizada a fenomenologia interpretativa e, como técnica de coleta de dados em profundidade, a amostra foi determinada pela saturação das informações, foram entrevistadas 6 mulheres que tiveram trabalho de parto, cada uma com três entrevistas, que foram transcritas pela pesquisadora. Resultados: fo r a m identificadas cinco categorias: 1. O acompanhamento faz a diferença na assistência de enfermagem, 2. O que a parturiente precisa: confiança, segurança e tranquilidade, 3. Encontrar um anjo, 4. A enfermeira me incentivou a seguir em frente, 5. O conhecimento do enfermeiro produz segurança na gestante. Foi possível determinar que, quando a gestante se sentia acompanhada, estabeleceu empatia com a enfermeira, conseguindo sentir confiança, tranquilidade e segurança, isso permitiu ter um relacionamento recíproco; Eles também enfatizam que a enfermeira fez um esforço para oferecer um cuidado mais próximo e centrado na pessoa. Conclusões: O cuidado prestado pelo enfermeiro significa mais do que intervenções assistenciais competentes, implica criar empatia, criar confiança, tranquilidade, segurança, fomentada pelo apoio prestado à gestante. (AU)


Subject(s)
Humanizing Delivery , Trust , Nurse-Patient Relations , Nursing Care
16.
Hipertens. riesgo vasc ; 37(3): 133-136, jul.-sept. 2020. ilus, graf
Article in Spanish | IBECS | ID: ibc-193522

ABSTRACT

La disfunción autonómica es una enfermedad muy frecuente en las alfa-sinucleoinopatías (enfermedad de Parkinson, demencia por cuerpos de Lewy, atrofia multisistémica). A nivel cardiovascular puede producir síntomas como hipotensión ortostática, hipertensión supina o disminución de la respuesta de la frecuencia cardiaca a estímulos. Para el diagnóstico es fundamental una sospecha clínica y una exploración física minuciosa, tomando la presión arterial tanto en posición de decúbito supino como en bipedestación. El electrocardiograma puede mostrar un alargamiento de los intervalos PR y QT, mientras que la monitorización ambulatoria de presión arterial de 24 h aporta información sobre los patrones de presión arterial. La confirmación de la disfunción simpática cardiaca puede realizarse con una gammagrafía miocárdica de inervación con 123-I-metilbencilguanidina (123-I-MIBG), ya que refleja la captación noradrenérgica neuronal específica. A continuación presentamos el caso de un varón con enfermedad de Parkinson que tras un completo estudio fue diagnosticado de disfunción autonómica cardiovascular


Autonomic dysfunction is a common condition in the alpha-synucleinopathies (Parkinson's disease, dementia with Lewy bodies, multiple system atrophy). Cardiovascular symptoms may include orthostatic hypotension, supine hypertension or decreased heart rate response. A clinical suspicion and physical examination are essential for diagnosis, taking blood pressure in supine and standing positions. The electrocardiogram may show a prolongation of the PR and QT intervals, while 24-hour ambulatory blood pressure monitoring provides information on blood pressure patterns. Cardiac sympathetic dysfunction can be confirmed by an innervation myocardial scintigraphy with 123-I-methylbenzylguanidine (123-I-MIBG). This can reflect specific neuronal noradrenergic uptake.We present the case of a man with Parkinson's disease who was diagnosed with cardiovascular autonomic dysfunction after a complete study


Subject(s)
Humans , Male , Aged, 80 and over , Autonomic Nervous System Diseases/complications , Autonomic Nervous System Diseases/diagnostic imaging , Neurodegenerative Diseases/complications , Arterial Pressure/drug effects , Autonomic Nervous System Diseases/physiopathology , Severity of Illness Index , Electrocardiography , Heart Rate , Captopril , Long QT Syndrome/diagnosis
17.
J Assist Reprod Genet ; 37(6): 1379-1385, 2020 Jun.
Article in English | MEDLINE | ID: mdl-32363563

ABSTRACT

PURPOSE: To investigate the clinical efficacy of a "Universal Warming" protocol, based on subsequent steps with 1 M and 0.5 M concentration of extracellular cryoprotectant (ECCP), on shipped oocytes. Oocytes are vitrified using different brands of ready-to-use kits which recommend that the use of their own warming kit and combining different vitrification/warming kits may have legal consequences for assisted reproductive (AR) centers, until this practice has been validated with clinical studies. METHODS: Retrospective multi-center transnational observational study. Number of oocytes warmed 1.898. Vitrification performed with vitrification kit (Kitazato, Japan); warming carried out randomly with two different kits: Kitazato warming kit and Vit Kit®-Thaw (FujiFilm Irvine, USA). Warmed oocytes were assigned to 2 groups: KK (Kitazato/Kitazato) 939, and KI (Kitazato/Irvine) 959. Primary endpoint: survival rate. Secondary endpoints: fertilization rate; blastulation rate; implantation rate; live birth rate. RESULTS: Survival was comparable between the groups: 84.6% (795/939) in group KK vs 82.1% (787/959) in group KI. Fertilization rate was lower (P = 0.027) in group KK (75.7%-602/795) than in group KI (80.4%-633/787). Blastulation and implantation and live birth rates were all statistically comparable between the study groups: blastulation rate was 58.5% (352/602) vs 57.8% (366/633); implantation rate was 41.5% (80/193) vs 45.9% (84/183); live birth rate was 52.5% (62/118) in KK and 45.0% (54/120) in KI. CONCLUSION: The use of this "Universal Warming" protocol simplifies vitrified oocyte exchange between AR centers in different countries, and overcomes potential regulatory/commercial/availability differences affecting clinical practice.


Subject(s)
Birth Rate , Embryo Implantation/physiology , Embryo Transfer , Oocytes/growth & development , Adult , Cryopreservation , Female , Fertilization in Vitro , Humans , Japan , Live Birth/epidemiology , Oocyte Donation , Oocyte Retrieval/methods , Pregnancy , Pregnancy Rate , Vitrification
18.
Hipertens Riesgo Vasc ; 37(3): 133-136, 2020.
Article in Spanish | MEDLINE | ID: mdl-32224047

ABSTRACT

Autonomic dysfunction is a common condition in the alpha-synucleinopathies (Parkinson's disease, dementia with Lewy bodies, multiple system atrophy). Cardiovascular symptoms may include orthostatic hypotension, supine hypertension or decreased heart rate response. A clinical suspicion and physical examination are essential for diagnosis, taking blood pressure in supine and standing positions. The electrocardiogram may show a prolongation of the PR and QT intervals, while 24-hour ambulatory blood pressure monitoring provides information on blood pressure patterns. Cardiac sympathetic dysfunction can be confirmed by an innervation myocardial scintigraphy with 123-I-methylbenzylguanidine (123-I-MIBG). This can reflect specific neuronal noradrenergic uptake. We present the case of a man with Parkinson's disease who was diagnosed with cardiovascular autonomic dysfunction after a complete study.


Subject(s)
Autonomic Nervous System Diseases/diagnosis , Cardiovascular Diseases/diagnosis , Parkinson Disease/complications , Aged, 80 and over , Autonomic Nervous System Diseases/etiology , Autonomic Nervous System Diseases/physiopathology , Blood Pressure , Cardiovascular Diseases/etiology , Cardiovascular Diseases/physiopathology , Electrocardiography , Humans , Male
20.
Rehabilitacion (Madr) ; 54(1): 31-40, 2020.
Article in Spanish | MEDLINE | ID: mdl-32007181

ABSTRACT

OBJECTIVE: To describe the characteristics of motor behaviour in premature infants during the first months of postnatal life, according to the available evidence. MATERIALS AND METHODS: A systematic literature review was carried out; this method forms part of secondary studies under investigation and describes a phenomenon in detail based on primary sources of information. RESULTS: The literature search in the databases consulted yielded 7,228 articles; of these, 15 more were identified through "snowball" search strategies. At the start of the screening process, 63 eligible records were chosen based on their title and summary, and 14 were excluded because they were duplicates. A total of 49 articles were selected for a full text revision and, of these, 37 were excluded because they did not meet all the inclusion criteria. Finally, 12 articles were selected to prepare the qualitative synthesis of the present research work. CONCLUSIONS: In comparison with neonates born at term, premature infants demonstrate a particular motor repertoire, due to the immaturity of their systems; their motor behaviour follows a line of development mainly characterised by deficits in muscle tone, postural control, muscle balance, and antigravity muscle activation.


Subject(s)
Infant, Premature/physiology , Motor Activity/physiology , Humans , Infant , Infant, Newborn , Muscle Tonus/physiology , Muscle, Skeletal/physiology , Postural Balance/physiology
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