ABSTRACT
No disponible
Subject(s)
Humans , Fibrinolytic Agents/administration & dosage , Endoscopy, Digestive System/methods , Blood Loss, Surgical/prevention & control , Thrombosis/prevention & control , International Normalized Ratio/classification , Withholding Treatment/statistics & numerical data , Contraindications, DrugABSTRACT
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Subject(s)
Humans , Female , Aged , Calcinosis , Splenic Diseases , Incidental Findings , Diagnosis, DifferentialABSTRACT
Local hepatic tuberculosis without active pulmonary or miliary tuberculosis is an uncommon diagnosis. Even less common is the finding of a nodular form of local hepatic tuberculosis. There is a growing incidence of the disease related to human immunodeficiency virus. The authors report a case of pseudotumoral hepatic tuberculosis in a patient without AIDS, manifesting as prolonged fever, diagnosed previously as metastatic liver. Imaging studies of the liver and laparoscopic findings suggested metastatic disease. The correct diagnosis was made by histology of biopsies obtained in laparoscopy, which is an easy and cheap method, with less morbidity and mortality than surgical intervention. The case report illustrates the difficulty in reaching the correct diagnosis, most often confused with carcinoma of the liver, primary or metastatic. A greater awareness of this rare clinical entity may prevent needless surgical intervention since the majority of patients respond well to antituberculous chemotherapy.
Subject(s)
Laparoscopy , Liver Neoplasms/diagnosis , Tuberculosis, Hepatic/diagnosis , Aged , Biopsy , Diagnosis, Differential , Humans , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/pathology , Male , Tomography, X-Ray Computed , Tuberculosis, Hepatic/diagnostic imaging , Tuberculosis, Hepatic/pathologyABSTRACT
UNLABELLED: Porphyria cutanea tarda (PCT) is caused by reduced activity of hepatic uroporphyrinogen decarboxylase. However extrinsic factors such as alcohol abuse and drug intake are required for the clinical manifestation of the disease. Hepatitis C virus antibodies have been detected in a high percentage of patients with PCT. Hepatitis C virus is probably the main pathogenetic factor of liver damage in patients with PCT. AIM: To study the association between hepatitis C virus and PCT in our patients with PCT. MATERIAL AND METHODS: We have investigated six patients diagnosed of PCT in order to detect the presence of hepatitis C virus and other possible causes of the disease. RESULTS: We have found that 66% of our patients had hepatitis C virus antibodies, 50% ethanol abuse, of which 2/3 presented hepatitis C virus antibodies, and one case of HIV.
Subject(s)
Hepacivirus/immunology , Hepatitis C Antibodies/analysis , Hepatitis C/complications , Hepatitis, Chronic/complications , Porphyria Cutanea Tarda/complications , Adult , Alcoholism/complications , Biopsy , Enzyme-Linked Immunosorbent Assay , HIV Seropositivity/complications , Hepacivirus/genetics , Hepacivirus/isolation & purification , Hepatitis C/diagnosis , Hepatitis, Chronic/diagnosis , Humans , Liver/pathology , Male , Middle Aged , Polymerase Chain Reaction , Porphyria Cutanea Tarda/diagnosis , RNA, Viral/analysisABSTRACT
Sarcoidosis is a granulomatous disease of unknown origin with a variable clinical presentation. Although involvement of every organ has been described, the pulmonary system is most frequently involved. Isolated extrapulmonary disease is rare. Hepatic manifestations include granulomatous hepatitis and hilar lymphadenopathy. We describe a case of sarcoidosis initially presenting as extrahepatic jaundice.
Subject(s)
Liver Diseases/diagnosis , Pancreatic Neoplasms/diagnosis , Sarcoidosis/diagnosis , Adult , Cholestasis/etiology , Diagnosis, Differential , Female , Humans , Liver Diseases/complications , Sarcoidosis/complications , Tomography, X-Ray ComputedABSTRACT
Wegener's granulomatosis is a necrotizing granulomatous vasculitis often characterized by involvement of the upper respiratory tract, lungs and kidney, although any organic system can be affected. We present the case of a female patient with Wegener's granulomatosis diagnosed by biopsy of the kidney, and severe gastrointestinal bleeding with fatal course. Endoscopic findings of the colon and the histopathology of the biopsy are discussed.
