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Prevalence of extended-spectrum beta-lactamases in South America.

Villegas, M V; Kattan, J N; Quinteros, M G; Casellas, J M.

Clin Microbiol Infect ; 14 Suppl 1: 154-8, 2008 Jan.

Article in English | MEDLINE | ID: mdl-18154539

ABSTRACT

In South American countries, the class A extended-spectrum beta-lactamases (ESBLs) so far recognised belong to the CTX-M, Pseudomonas Extended Resistance (PER), SHV and TEM families. ESBL rates in South America are among the highest in the world, probably due to multiple factors. SHV- and TEM-type ESBLs have been frequently encountered, but CTX-M is endemic and widely dominant. PER-type ESBLs seem to be restricted to the southern 'cone' of South America. Community-acquired ESBLs are starting to appear.

Subject(s)

Gram-Negative Bacteria/enzymology , Gram-Negative Bacterial Infections/epidemiology , beta-Lactamases/biosynthesis , beta-Lactamases/classification , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Child, Preschool , Gram-Negative Bacteria/drug effects , Gram-Negative Bacterial Infections/microbiology , Humans , Prevalence , South America/epidemiology , beta-Lactam Resistance

ABSTRACT

Subject(s)

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