[Cytomegalic inclusion disease. Report of a case in a newborn]. / Enfermedad de inclusión citomegálica. Reporte de un recién nacido.

A clinical case of this disease in a newborn is reported. The clinical signs and laboratory results were typical and were confirmed by pathological studies. The modern literature stresses the high frequency of this disease, specially in the U.S.A. and England, where reports reach 4% in pregnant women and 1% of newborns with cytomegalic inclusion disease. We do not know its frequency in Mexico.

[Congenital syphilis, intrauterine radiologic diagnosis]. / Sífilis congénita, diagnóstico radiológico intrauterino.

The present work includes six cases of congenital syphilis that were diagnosed radiologically before birth in patients with positive syphilitic reactions who had not been given treatment during gestation. The x-ray diagnosis was mainly based on lesions of diaphyses and metaphyses of the long bones of the fetal skeleton that were identified in lateral projection of x-ray plates of the maternal abdomen. In all cases reported, x-ray plates were taken in the immediate post-partum period with confirmation of the bony lesions and at the same time, of the laboratory tests including blood picture and liver function test in 5 cases. Autopsy was practiced in one case.

[Multicystic kidney in the newborn]. / Riñón multiquístico en el recién nacido.

Fourteen cases of multicystic kidney were identified out of 153,825 births through five and a half years at the "Dr. Ignacio Morones Prieto" hospital in Monterrey, Nuevo León. The etiopathogenesis and heredity in this disease are not clear. An early diagnosis is possible following a careful abdominal examination. The left kidney is the one most frequently involved. The excretory urography only shows renal exclusion of the affected side; when the disease is of only one side there is good excretion of the opaque medium by the contralateral kidney. The kidney is substituted by an irregular mass made up of multiple cysts losing the aspects of a normal kidney. Microscopically, its architecture is completely lost and there is replacement by cysts and some occasional hypoplastic glomeruli. If the opposite kidney is not affected, the prognosis is good. Nephrectomy must be done. Differential diagnosis must be made with hydronephrosis, nephroblastoma and thrombosis of the renal vein.

[Epidermolysis bullosa of the newborn]. / Epidermólisis bulosa del recién nacido.

Nine cases of epidermolysis bullosa of the newborn are reported. Three cases corresponded to the simple type; 4 were dystrophic and two belonged to the letal phase. Those of the letal variety died from septicemia, while simple and dystrophic varieties are under hospital control at the out-patient department.

[Perinatal morbimortality]. / Morbimortalidad perinatal.

Between 1972 and 1975 (4 years), the Hospital de Ginecoobstetricia "Dr. Ignacio Morones Prieto" of the I.M.S.S. at Monterrey, N.L., reported a birth rate of 106, 771 with 98.35% (105,004) live borns. The morbidity rate was 262.06/1000 live borns and the perinatal mortality was 31.24/1000, divided into antenatal 16.54/1000 and posnatal 14.70/1000. Within morbidity, prematurity and/or low weight occupies the first place, followed by respiratory pathology and afterwards, jaundice, infections, obstetric trauma and finally, congenital malformations. The neonatal mortality reached 14.70/1000 live borns and if we consider gestational age, 22.9% corresponds to immature products, 50.2% prematures and 26.0% to full-term products. In relation to hours of life, we find that 62.50% of the total number of deaths were reported in products less than 24 hrs. of life and 37.50%, in products over 24 hrs. of life.

PIP: The article reports figures of perinatal morbimortality gathered in a large metropolitan hospital in Mexico between 1972 and 1975. Of 106,771 births, 98.34% were live births, 1.65% were stillbirths, 7.23% were preterm births, 0.35% were immature babies, and 92.41% were births at full term. Morbidity rate was 262.06/1000, and perinatal mortality was 32.24/1000. Major causes of morbidity were, in order of decreasing importance, prematurity and low birth weight, respiratory pathology, jaundice, several types of infection, obstetrical traumas, and congenital malformations. Neonatal mortality accounted for 14.70/1000 live births, and of these, 22.9% were immature products, 50.2% premature, and 26.9% were full term babies. 62.50% of total number of deaths occurred within 24 hours of life, and 37.50% after 24 hours of life. Compared to other industrialized countries these infant mortality rates are still very high; they are, however, a great improvement over mortality rates in Mexico as measured a few years ago.