ABSTRACT
Objetivo: estudiar la influencia de la morfología del espermatozoide seleccionado para inyección intracitoplasmática de espermatozoides sobre la tasa de gestaciones tras la realización de la técnica. Material y métodos: análisis retrospectivo de 174 parejas sometidas a inyección intracitoplasmática. Estudio descriptivo de las variables del seminograma y de variables clínicas de la mujer, así como un análisis multivariante de regresión logística de las mismas para valorar su influencia en el éxito de inyección intracitoplasmática de espermatozoides. Resultados: encontramos que la morfología del espermatozoide usado para la fecundación se manifiesta como factor independiente de influencia negativa, OR de 2,94 [IC 95% (1,10-7,83)], junto con una edad mayor de 35 años, OR 1,98 [IC 95% (1,03-3,81)], para el éxito de la inyección intracitoplasmática de espermatozoides. Conclusiones: la morfología del espermatozoide inyectado influye negativamente en la tasa de embarazos bioquímicos tras inyección intracitoplasmática de espermatozoides, apoyando por lo tanto, que es una buena técnica, ya que permite seleccionar espermatozoides de morfología normal en pacientes con teratozoospermia (AU)
Objective: To study the influence of spermatozoa morphology selected for intracytoplasmic sperm injection on the rate of pregnancies after the completion of the technique. Material and Methods: Retrospective analysis of 174 couples undergoing Intracytoplasmic sperm injection. Descriptive study of seminogram variables, clinical variables of women and a multivariate logistic regression analysistoassesstheinfluenceonthesuccess of Intracytoplasmic sperm injection. Results: We found that the morphology of the spermatozoa used for fertilization is manifested as an independent factor of negative influence, OR 2.94 [95% CI (1.10 to 7.83)], together with an age over 35 years, OR 1, 98 [95% CI (1.03 to 3.81)], for the success of Intracytoplasmic sperm injection. Conclusions: Abnormal spermatozoa morphology injected influences negatively in the rate of biochemical pregnancies, supporting therefore the Intracytoplasmic sperm injection as a good technique because it allows us to select normal spermatozoa morphology in patients with teratozoospermia (AU)
Subject(s)
Humans , Male , Female , Sperm Injections, Intracytoplasmic/instrumentation , Sperm Injections, Intracytoplasmic/methods , Ovulation Induction/methods , Sperm Injections, Intracytoplasmic/statistics & numerical data , Spermatozoa/physiology , Retrospective Studies , Multivariate Analysis , Logistic Models , Semen/cytology , Semen Analysis/methods , Cohort Studies , 28599ABSTRACT
OBJECTIVE: The aim of this study is to evaluate the use of hysteroscopic Essure device placement for the treatment of hydrosalpinx (HS)-related infertility in patients with laparoscopic contraindications and compared their pregnancy outcomes following IVF-ICSI treatment with those patients having had laparoscopic tubal occlusion (LTO). PATIENTS: From 2008 to 2014 a total of 50 patients were diagnosed with unilateral or bilateral hydrosalpinges: 29 patients had laparoscopic contraindications and were treated hysteroscopically and 21 patients were treated with laparoscopical salpingectomy. RESULTS: Of the 29 patients who underwent treatment with Essure(®), 21 began a cycle of in vitro fertilization (IVF), and 13 finished in embryo transfer that resulted in seven clinical pregnancies. Furthermore, in the group of women treated with salpingectomy, 17 started an IVF cycle that resulted in 12 clinical pregnancies. The clinical pregnancy rate per patient with an IVF cycle started was 33.3% and 70.6%, the live-birth rate per patient was 14.3% and 52.9%, the miscarriage rate was 57.1% and 18.2%, and the implantation rate was 16.3% and 34.1% for hysteroscopy and laparoscopy, respectively. CONCLUSION: Essure(®) placement is an alternative method for occlusion of hydrosalpinges before IVF. Monitoring the live-birth rate confirms that this option may be considered when laparoscopy is impossible or contraindicated.
