ABSTRACT
OBJECTIVES: To investigate the association between pain and peripatellar-synovitis on static and dynamic contrast-enhanced MRI in knee osteoarthritis. METHODS: In a cross-sectional setting, knee synovitis was assessed using 3-Tesla MRI and correlated with pain using the knee injury and osteoarthritis outcome score (KOOS). Synovitis was assessed in the peripatellar recesses with: (i) dynamic contrast-enhanced (DCE)-MRI, using both pharmacokinetic and heuristic models, (ii) contrast-enhanced (CE)-MRI, and (iii) non-CE-MRI. The DCE-MRI variable IRExNvoxel was chosen as the primary variable in the analyses. RESULTS: Valid data were available in 94 persons with a mean age of 65 years, a BMI of 32.3kg/m(2) and a mean Kellgren-Lawrence grade of 2.5. IRExNvoxel showed a statically significant correlation with KOOS-Pain (r=-0.34; p=0.001), as was the case with all DCE-variables but one. Correlations between static MRI-variables and KOOS-Pain ranged between -0.21Subject(s)
Contrast Media
, Image Enhancement/methods
, Magnetic Resonance Imaging/methods
, Osteoarthritis, Knee/diagnostic imaging
, Pain Measurement/statistics & numerical data
, Synovitis/diagnostic imaging
, Aged
, Contrast Media/administration & dosage
, Cross-Sectional Studies
, Female
, Gadolinium/administration & dosage
, Heterocyclic Compounds/administration & dosage
, Humans
, Image Processing, Computer-Assisted/methods
, Knee Joint/diagnostic imaging
, Male
, Middle Aged
, Organometallic Compounds/administration & dosage
, Patella/diagnostic imaging
, Reproducibility of Results
, Self Report