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4.
Rev Neurol ; 46(6): 373-8, 2008.
Article in Spanish | MEDLINE | ID: mdl-18368683

ABSTRACT

INTRODUCTION AND DEVELOPMENT: There is a close relation between female sex hormones and migraine. Before puberty the incidence of migraine is the same in both sexes, but it becomes three times more frequent in females following menarche. Thus, approximately 25% of females of reproductive age suffer migraine versus 8% of males; above the age of fifty, however, the prevalence is again similar in the two sexes. Other evidence backing this theory include the existence of menstrual migraines, improvements in migraines between the fourth and ninth month of pregnancy and the fact that both contraceptives and hormone replacement therapy can modify the frequency and intensity of migraines. The changes in the characteristics of the migraines of females in different phases of their lives, such as puberty, pregnancy, lactation, menopause, and while they are using contraceptives or hormone replacement therapy, are closely related to the concentrations of estrogens in the blood. This relation is even closer in the case of migraine without aura. AIMS: The aim of this study was to review the changes that take place in the characteristics of the migraines suffered by women in the different stages of their lives (menstruation, pregnancy, lactation and menopause), as well as when using contraceptives and hormone replacement therapy. We also sought to examine the therapeutic options that are indicated in each situation.


Subject(s)
Migraine Disorders , Contraceptives, Oral , Female , Humans , Menopause , Menstruation , Migraine Disorders/etiology , Migraine Disorders/therapy , Sex Factors
5.
Rev. neurol. (Ed. impr.) ; 46(6): 373-378, 16 mar., 2008.
Article in Es | IBECS | ID: ibc-65439

ABSTRACT

Existe una estrecha relación entre las hormonas sexuales femeninas y la migraña. La incidenciade la migraña es igual en ambos sexos antes de la pubertad, pero es tres veces más frecuente en las mujeres tras la menarquia.Así, aproximadamente el 25% de las mujeres en edad reproductiva sufre migraña frente al 8% de los varones, mientras que después de la quinta década de la vida la prevalencia es similar en ambos sexos. Otras evidencias que apoyan esta teoría son la existencia de la migraña menstrual, la mejoría de la migraña durante el segundo y el tercer trimestre del embarazo y elhecho de que tanto los anticonceptivos como la terapia hormonal sustitutiva puedan modificar la frecuencia y la intensidad de la migraña. Los cambios en las características de la migraña que presentan las mujeres en distintas fases de su vida, como lapubertad, el embarazo, la lactancia, la menopausia, y durante el empleo de de anticonceptivos o de terapia hormonal sustitutiva, están en íntima relación con las concentraciones en sangre de estrógenos. Esta relación es más estrecha en la migraña sin aura. Objetivos. Revisar los cambios en las características de las migrañas que experimentan las mujeres en distintos estadios de su vida (menstruación, embarazo, lactancia y menopausia), así como con el empleo de métodos anticonceptivos y terapia hormonal sustitutiva, y las opciones terapéuticas indicadas en cada situación


There is a close relation between female sex hormones and migraine. Before puberty the incidence of migraine is the same in both sexes, but it becomes three times more frequent in females following menarche. Thus, approximately 25% of females of reproductive age suffer migraine versus 8% of males; above the age of fifty, however, the prevalence is again similar in the two sexes. Other evidence backing this theory include the existence of menstrual migraines, improvements in migraines between the fourth and ninth month of pregnancy and the fact that both contraceptives and hormone replacement therapy can modify the frequency and intensity of migraines. The changes in the characteristics of the migraines of females in different phases of their lives, such as puberty, pregnancy, lactation, menopause, and while they are using contraceptives or hormone replacement therapy, are closely related to the concentrations of estrogens in the blood. This relation is even closer in the case of migraine without aura. Aims. The aim of this study was to review the changes that take place in the characteristics of the migraines suffered by women in the different stages of their lives(menstruation, pregnancy, lactation and menopause), as well as when using contraceptives and hormone replacement therapy. We also sought to examine the therapeutic options that are indicated in each situation


Subject(s)
Humans , Female , Migraine Disorders/epidemiology , Sex Distribution , Age Distribution , Gonadal Steroid Hormones/analysis , Contraceptives, Oral, Hormonal/pharmacokinetics , Hormone Replacement Therapy , Risk Factors , Breast Feeding , Menopause
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