ABSTRACT
We report here the case of a Prosthetic Joint Infection (PJI) associated with Coxiella burnetii in a 62-year-old man with a revised total hip arthroplasty. The diagnosis was performed first by 16S rDNA sequencing on hip fluid aspirate, and confirmed by specific qPCR. Q fever has been reported in few cases of Prosthetic Joint Infections, often associated with chronic evolution and iterative surgeries. This case report alerts about such an unexpected diagnosis in a patient with no known risk factors.
Subject(s)
Coxiella burnetii/isolation & purification , Joint Diseases/microbiology , Prosthesis-Related Infections/microbiology , Q Fever/microbiology , Coxiella burnetii/genetics , Humans , Male , Middle Aged , Prostheses and Implants/microbiology , Q Fever/diagnosisSubject(s)
Leukemia, Myeloid, Acute , Lung Diseases , Mucormycosis , Nose Diseases , Pancytopenia , Triazoles/administration & dosage , Aged , Amphotericin B/administration & dosage , Antifungal Agents/administration & dosage , Humans , Immunocompromised Host , Leukemia, Myeloid, Acute/blood , Leukemia, Myeloid, Acute/pathology , Leukemia, Myeloid, Acute/therapy , Lung Diseases/diagnosis , Lung Diseases/drug therapy , Lung Diseases/microbiology , Lung Diseases/physiopathology , Male , Mucormycosis/drug therapy , Mucormycosis/etiology , Mucormycosis/immunology , Mucormycosis/physiopathology , Nose Diseases/diagnosis , Nose Diseases/drug therapy , Nose Diseases/immunology , Nose Diseases/microbiology , Pancytopenia/diagnosis , Pancytopenia/etiology , Treatment OutcomeABSTRACT
Optic nerve involvement may occur in various infectious diseases, but is rarely reported after infection by the human immunodeficiency virus (HIV). We report the atypical case of a 38-year-old patient in whom the presenting features of HIV infection were due to a bilateral optic neuropathy associated with macular subretinal fluid and cystoid macular edema, which responded well to antiretroviral therapy.
Subject(s)
HIV Infections/complications , Macular Edema/virology , Optic Nerve Diseases/virology , Vision Disorders/virology , Adult , HIV Infections/pathology , Humans , Macula Lutea/pathology , Macular Edema/pathology , Male , Optic Nerve/pathology , Optic Nerve Diseases/pathology , Vision Disorders/pathologyABSTRACT
We present a case report of Mycobacterium malmoense in a 53-year-old white man. The incidence of M. malmoense infections is a rare event compared with other nontuberculous mycobacteria, but it has increased since 1980, especially in northern Europe. Many patients have disposing underlying diseases. In most cases, it is a pulmonary infection. The most frequent used antibiotics are rifampicin (or rifabutin), ethambutol, and clarithromycin.