ABSTRACT
Free flap reconstruction in infants is extremely rare. A seven-and-a-half-month-old male infant sustained an extensive soft tissue defect on his left knee caused by extravasation of an intraosseous arterenol infusion. A free latissimus dorsi flap was successfully performed for soft tissue reconstruction. Indications, advantages, and outcome of the procedure are discussed.
Subject(s)
Free Tissue Flaps , Limb Salvage/methods , Lower Extremity/surgery , Soft Tissue Injuries/surgery , Humans , Infant , Male , Norepinephrine/adverse effects , Soft Tissue Injuries/chemically inducedSubject(s)
Antibodies, Monoclonal/therapeutic use , Complement Inactivating Agents/therapeutic use , Graft Survival/drug effects , Hemolytic-Uremic Syndrome/surgery , Kidney Transplantation , Antibodies, Monoclonal/pharmacology , Antibodies, Monoclonal, Humanized , Child , Complement Activation/drug effects , Complement C3/metabolism , Complement Factor H/genetics , Complement Inactivating Agents/pharmacology , Hemolytic-Uremic Syndrome/drug therapy , Humans , Male , Mutation , Secondary PreventionABSTRACT
The reported cases of infant tick-borne encephalitis give the impression that the morbidity in this age group is negligible. We describe the first report of infection in the neonatal period that resulted in severe neurologic impairment. All persons living in or traveling to endemic areas should be protected by vaccination. This applies equally and especially to women of childbearing age. Transplacental transfer of antibody after vaccination has been observed and could provide protection to unvaccinated newborns preventing or alleviating the potential devastating impact of this disease.
