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1.
Chirurgie (Heidelb) ; 94(3): 256-264, 2023 Mar.
Article in German | MEDLINE | ID: mdl-36418574

ABSTRACT

BACKGROUND: Due to an increasing competence orientation of medical studies, surgical curricula are being adapted in many places. In addition to surgical knowledge and practical skills, these should also teach competencies in differential diagnostics and treatment. The teaching of surgical knowledge through lectures and seminars and the demonstration of practical skills, e.g., through the use of logbooks in the Bock Practical Surgery (BP), only allows limited active engagement with surgical competencies on differential diagnostics and treatment. A reflection-based portfolio allows, through the independent written elaboration of surgical topics, an active engagement with the competencies and promises a higher learning effect. In the context of the implementation of such a portfolio as part of the proof of activity in BP, the effects on the acquisition of competencies and on the way of learning were investigated. MATERIAL AND METHODS: Using a mixed methods approach, we compared competence acquisition using a reflection-based portfolio with learning using a logbook. Students conducted a self-assessment of competencies using questionnaire surveys before and after the BP. Through focus group interviews with discussions among students using a guideline, we explored the different ways of acquiring competencies. In addition, the examination and evaluation results of both cohorts were compared. RESULTS AND DISCUSSION: Students' self-assessed competency acquisition and examination and evaluation results showed no differences when comparing the two cohorts. During the focus group interviews, we were able to show that in the perception of the students, surgical competencies can be made more visible and thus more explicit with the help of a reflection-based portfolio. In addition, self-regulated learning was promoted without neglecting practical skills. Students demanded greater supervision and guidance by mentors in both groups.


Subject(s)
Education, Medical, Undergraduate , Humans , Education, Medical, Undergraduate/methods , Students , Clinical Competence , Educational Measurement/methods , Focus Groups
4.
Am J Emerg Med ; 32(10): 1300.e1-2, 2014 Oct.
Article in English | MEDLINE | ID: mdl-24848416

ABSTRACT

Thoracic injury following a major trauma can be life threatening. Veno-venous extracorporeal membrane oxygenation (vv-ECMO) can be used as a support to mechanical ventilation when acute respiratory distress syndrome is present. We report the case of an 18-year-old male driver who strayed from the road and fell 15 m into a backyard by landing on the roof of its car. The injury severity score was 51 for his pattern of injuries (hemopneumothorax left, sternum fracture, pneumothorax right, pneumomediastinum, intracerebral bleeding, scalping injury occipital, fracture of the ninth thoracic vertebral body, and complete paraplegia). The patient was transferred to our hospital 12 hours after the accident. As we started the secondary survey, the patient was cannulated for vv-ECMO due to deterioration in his oxygenation status. We implanted a double-lumen cannula (Avalon31F catheter, right internal jugular vein) during fluoroscopy. The patient developed posttraumatic systemic inflammatory response syndrome, which began to resolve after 72 hours, and he started breathing spontaneously. After 7 days, he was weaned from vv-ECMO and recovered in a rehabilitation facility. The use of vv-ECMO therapy in cases of major trauma has become a rescue strategy. The use of vv-ECMO was performed without anticoagulation because of his traumatic brain injury and severe spinal cord injury.


Subject(s)
Accidents, Traffic , Brain Injuries/complications , Extracorporeal Membrane Oxygenation/methods , Respiratory Distress Syndrome/therapy , Spinal Cord Injuries/complications , Spinal Fractures/complications , Systemic Inflammatory Response Syndrome/etiology , Adolescent , Humans , Injury Severity Score , Male , Respiratory Distress Syndrome/etiology
5.
Yeast ; 12(6): 523-9, 1996 May.
Article in English | MEDLINE | ID: mdl-8771707

ABSTRACT

All eight of the CCT1-CCT8 genes encoding the subunits of the Cct chaperonin complex in Saccharomyces cerevisiae have been identified, including three that were uncovered by the systematic sequencing of the yeast genome. Although most of the properties of the eukaryotic Cct chaperonin have been elucidated with mammalian systems in vitro, studies with S. cerevisiae conditional mutants revealed that Cct is required for assembly of microtubules and actin in vivo. Cct subunits from the other yeasts, Candida albicans and Schizosaccharomyces pombe, also have been identified from partial and complete DNA sequencing of genes. Cct8p from C. albicans, the only other completely sequenced Cct protein from a fungal species other than S. cerevisiae, is 72% and 61% similar to the S. cerevisiae and mouse Cct8 proteins, respectively.


Subject(s)
Candida albicans/genetics , Chaperonins/genetics , Saccharomyces cerevisiae/genetics , Schizosaccharomyces/genetics , Actins/physiology , Amino Acid Sequence , Microtubule Proteins/physiology , Molecular Sequence Data , Mutagenesis , Protein Structure, Secondary , Protein Structure, Tertiary , Sequence Homology, Amino Acid
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