Subject(s)
Respiratory Distress Syndrome, Newborn/therapy , Ventilators, Mechanical/adverse effects , Bronchopulmonary Sequestration/etiology , Hemoptysis/etiology , Humans , Hyaline Membrane Disease/therapy , Iatrogenic Disease , Infant, Newborn , Pneumonia/etiology , Pulmonary Atelectasis/etiologyABSTRACT
We report the case of a boy aged 9 1/2 years with hyperosmolar, nonketotic diabetic coma. He was not known to be diabetic prior to the onset of coma. Pathogenetic aspects of this rare manifestation of juvenile diabetes are discussed. It is dangerous to decrease osmolarity too rapidly during infusion of very hypotonic solutions. Treatment with continuous low-dose insulin infusion may cautiously be tried.
Subject(s)
Diabetes Mellitus, Type 1/complications , Diabetic Coma/drug therapy , Hyperglycemic Hyperosmolar Nonketotic Coma/drug therapy , Insulin/administration & dosage , Child , Humans , Male , Osmolar Concentration , Time FactorsABSTRACT
Successive manifestations of acute air leak phenomenona are reported in a ventilated premature infant with aspiration of amniotic fluid. The increasingly reported incidence of pulmonary interstitial emphysema is emphasized. After its first occurrence there is a serious need for careful clinical and radiological observation because of the great risk of further complications.
Subject(s)
Infant, Premature, Diseases/therapy , Respiration, Artificial/adverse effects , Amniotic Fluid , Humans , Infant, Newborn , Infant, Premature , Pneumopericardium/etiology , Pneumoperitoneum/etiology , Pneumothorax/etiology , Pulmonary Emphysema/etiologyABSTRACT
Report of a 10 year old girl, who demonstrated the following diseases independent from each other: Phenylketonuria, Rubinstein-Taybi syndrome, dysplasias of the skeleton, especially dysplasia of the vertebra and finally, left-sided shrinkes adrenal gland, which caused presumably an increased production of androgens with a premature pubarche.
Subject(s)
Abnormalities, Multiple/complications , Adrenal Gland Diseases/complications , Mucopolysaccharidosis IV/complications , Phenylketonurias/complications , Rubinstein-Taybi Syndrome/complications , Spinal Diseases/complications , Abnormalities, Multiple/diagnostic imaging , Child , Female , Foot/diagnostic imaging , Hand/diagnostic imaging , Humans , Radiography , Spine/diagnostic imaging , SyndromeABSTRACT
A case of intense grey-brown discoloration of the skin, serum and urine in a premature twin is reported when phototherapy was used to reduce hyperbilirubinemia. All features made the diagnosis of bronze-baby-syndrome most probable. We were able to detect an increased level of coproporphyrin in serum. The patient did not show any signs of a kernicterus. Possible speculations about the pathogenetic and prognostic value of elevated levels of coproporphyrins in newborn infants under treatment with phototherapy are discussed. In these cases we must be aware of possible neurotoxic effects, since increased concentrations of bilirubin breakdown products may not be excreted as well through the normal biliary passage as normally.
